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Hyaluronic acid

Hyaluronic Acid Mechanisms of Action
Hyaluronic acid
Hyaluronic acid
CAS No.
9004-61-9
Chemical Name:
Hyaluronic acid
Synonyms
Mucoitin;Sepracoat;Hyaluronic acid;Hydluronic acid;Hyalobarrier gel;Haluronic acid、HA;Chlamyhyaluronic acid;HYALURONIC ACID SODIUM;HYALURONIC ACID NA-SALT;HYALURONICACID(HA)38%(BULK
CBNumber:
CB1176690
Molecular Formula:
C14H22NNaO11
Formula Weight:
403.31
MOL File:
9004-61-9.mol

Hyaluronic acid Properties

storage temp. 
−20°C
solubility 
H2O: 5 mg/mL, clear, colorless
form 
Lyophilized Powder
color 
White
Water Solubility 
Soluble in water.
EPA Substance Registry System
Hyaluronic acid(9004-61-9)

SAFETY

Hazard Codes  B
Safety Statements  22-24/25
WGK Germany  3
RTECS  MT7250000
3-10
TSCA  Yes
Hazardous Substances Data 9004-61-9(Hazardous Substances Data)

Hyaluronic acid price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar J60566 Hyaluronic acid, bovine vitreous humor 9004-61-9 10mg $149 2017-11-08 Buy
Alfa Aesar J60566 Hyaluronic acid, bovine vitreous humor 9004-61-9 50mg $535 2017-11-08 Buy
Alfa Aesar J60566 Hyaluronic acid, bovine vitreous humor 9004-61-9 100mg $1040 2017-11-08 Buy

Hyaluronic acid Chemical Properties,Uses,Production

Hyaluronic Acid

Hyaluronic acid is a completely transparent, non-adhesive, water-soluble and grease-free acid mucopolysaccharide. Its molecular weight is between a few hundred thousand to millions, and it makes up the dermis layer of the skin. Its unique molecular structure and physicochemical properties has many important physiological functions inside the body, such as lubricating joints, adjusting vascular permeability, adjusting proteins, diffusing and transporting water electrolytes, and promoting wound healing. Hyaluronic acid has a unique water retention effect and has the best known natural moisturizing properties, making it the ideal natural moisturizer.
Hyaluronic acid is an essential drug in ophthalmic “sticky surgeries”. It is used in cataract surgery, in which its sodium salt remains in the anterior chamber to maintain depth in the anterior chamber and ensure a clear surgical view. It reduces the occurences of postoperative inflammation and complications, thus improving the vision-correcting effects of the surgery. It is also used in complicated retinol detachment surgery. Hyaluronic acid has a low molecular weight and is considered the ideal natural moisturizing agent, so it is used as an additive in high-end makeup and as a moisturizer in creams, gels, lotions, masks, and serums. It is also used medically as a moisturizer to improve moisture retention and lubrication, and it also expands capillaries and improves skin health. For example, hyaluronic acid with a low molecular weight can be used as a lubricant in surgeries (such as knee surgery), while those with high molecular weight can be used as surgical lubricant and as a substitute for vitreous in ophthalmic surgery.

Mechanisms of Action

Hyaluronic acid’s main functions include:
  • Has excellent affinity to water and can regroup water within tissue for better retention and lubrication.
  • Folds to form a three-dimensional network and produces physiological effects, including producing fluid resistance, maintaining water balance and bodily stability, influencing macromolecule solubility, structure, chemical balance and system osmotic pressure, preventing the spread of pathogens, and promote the condensation of collagen fiber secretory substances.
  • Forms polymers with inseparable proteins to maintain tissue shape and size and to ensure reversible tissue compression resistance.
  • Affects macrophages, adherent cells, lymph cells, and natural killer cells.
  • Serves as an important part of interstitial fluid and is mainly metabolized in the liver. Liver fiber activity increases HA synthesis; combined with reduced function during cirrhosis, blood HA levels may increase abnormally.

Definition

ChEBI: A mucopolysaccharide composed of N-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates.

Hyaluronic acid Preparation Products And Raw materials

Raw materials

Preparation Products


Hyaluronic acid Suppliers

Global( 233)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 10013 55
Mainchem Co., Ltd.
0592-6210733
0592-6210733 sales@mainchem.com CHINA 1948 55
Henan DaKen Chemical CO.,LTD.
+86-371-55541817
inquiry@dakenchem.com CHINA 2900 58
Wuhan Landed Scientific Ltd. 027-88739577 18163556322
027-88739578 sales@landed.com.cn China 61 55
Xi'an boliante Chemical Co., Ltd. 17719597442
- 3570451756@qq.com China 3326 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96820 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) sh@meryer.com China 40398 62
INTATRADE GmbH +49 3493/605464
+49 3493/605470 sales@intatrade.de Germany 3588 66
future industrial shanghai co., ltd 021-61552785,400-0066-400
021-55660885 sales@jonln.com China 2090 65
Arden pharmaceutical &chemical Co., Ltd +86-(0)533-3595900 13793319233
+86-(0)533-3595900 info@chems.com.cn China 670 61

9004-61-9(Hyaluronic acid)Related Search:


  • 9004-61-9
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Carbohydrate
  • BioChemical
  • Activity Other
  • Activity
  • [BETA-SODIUM-GLUCONATE-(1,3)-BETA-N-ACETYL-D-GLUCOSAMINE-1,4-]N
  • COPOLY(BETA-GLUCURONIC ACID-[1->3]-BETA-N-ACETYLGLUCOSAMINE-[1->4] SODIUM SALT
  • HYALURONIC ACID NA-SALT
  • HYALURONIC ACID, SODIUM SALT, STREPTOCOCCUS SPECIES
  • HYALURONIC ACID SODIUM
  • HYALURONIC ACID HUMAN SODIUM SALT
  • Cytoskeleton and Extracellular Matrix
  • Extracellular Matrix
  • Extracellular Matrix Peptides and Proteins
  • Metabolomics
  • Metabolites and Cofactors on the Metabolic Pathways Chart
  • Metabolic Pathways
  • POLY(BETA-GLUCURONIC ACID-[1->3]-BETA-N-ACETYLGLUCOSAMINE-[1->4]), ALTERNATING
  • SODIUM HYALURONATE (STREPTOCOCCUS)
  • hyaluronic acid from bovine vitreous humor
  • Hyaluronic acid from Cockscomb
  • hyaluronic acid sodium from*streptococcus zooepid
  • Hyaluronic Acid Food /Cosmetic Grade /Injection 90.0% Min.
  • C14H22NO11Na
  • C14H21NO11n
  • HYALURONICACID(HA)38%(BULK
  • disodium 3-[3-acetamido-4-(6-carboxylato-3,4,5-trihydroxy-oxan-2-yl)oxy-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4,5-dihydroxy-oxane-2-carboxylate
  • C16H27NO12
  • Haluronic acid、HA
  • HYALURONIC ACID - FOOD GRADE
  • HYALURONIC ACID - INJECTABLE GRADE
  • HYALURONIC ACID - PHARMA GRADE
  • HYALURONIC ACID FOOD GRADE (VIA EXTRACTION)
  • HYALURONIC ACID INJECTION GRADE
  • Substrates
  • Hyaluronic acid
  • C14H22NO11種a
  • HYALURONIC ACID (SODIUM HYALURONATE)
  • Cnbio
  • Hydluronic acid
  • Chlamyhyaluronic acid
  • Hyalobarrier gel
  • Mucoitin
  • Sepracoat
  • Hyaluronic Acid from Bovine Vitreous Humor [Substrate for Hyaluronidase]
  • Hyaluronic Acid, from Human Umbilical Cords
  • sodiuM (2S,3S,4R,5R,6R)-3-((2S,3R,5S,6R)-3-acetaMido-5-hydroxy-6-(hydroxyMethyl)tetrahydro-2H-pyran-2-yloxy)-4,5,6-trihydroxytetrahydro-2H-pyran-2-carboxylate
  • hyaluronic acid/hyaluronic acid sodium
  • Hyaluronic acid, bovine vitreous humor
  • C14H21NO12n
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