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tert-Butyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate

CAS No.
112741-50-1
Chemical Name:
tert-Butyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate
Synonyms
(2S,3R)-tert-Butyl;(5R,6S)-N-Boc-5,6-diphenyl-2-morpholinone;6-oxo-2,3-diphenylMorpholine-4-carboxylate;(2S,3R)-(+)-N-Boc-6-oxo-2,3-diphenylMorpholine;2S,3R-6-oxo-2,3-diphenyl-4-morpholinecarboxylate;tert-butyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morph;(5S,6R)-(+)-4-Boc-5,6-diphenyl-2-Morpholinone, 99%;(2S,3R)-6-oxo-2,3-diphenylmorpholine-4-carboxylate;(5R,6S)-4-TERT-BUTOXYCARBONYL-5,6-DIPHENYLMORPHOLIN-2-ONE;(5S,6R)-4-tert-Butoxycarbonyl-5,6-diphenylmorpholin-2-one
CBNumber:
CB1239496
Molecular Formula:
C21H23NO4
Molecular Weight:
353.41
MDL Number:
MFCD00074953
MOL File:
112741-50-1.mol
MSDS File:
SDS
Last updated:2022-11-11 11:01:00

tert-Butyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Properties

Melting point 206 °C (dec.)(lit.)
Boiling point 509.6±50.0 °C(Predicted)
alpha 86 º (c=5.5 in methylene chloride)
Density 1.175±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka -3.28±0.60(Predicted)
optical activity [α]20/D +86°, c = 5.5 in methylene chloride
InChIKey MRUKRSQUUNYOFK-MOPGFXCFSA-N
CAS DataBase Reference 112741-50-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39
WGK Germany  3

tert-Butyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 331813 (2S,3R)-(+)-N-Boc-6-oxo-2,3-diphenylmorpholine 99% 112741-50-1 5g $441 2023-06-20 Buy
Sigma-Aldrich 331813 (2S,3R)-(+)-N-Boc-6-oxo-2,3-diphenylmorpholine 99% 112741-50-1 1g $97.8 2023-01-07 Buy
TRC B699835 (2S,3R)-(+)-N-Boc-6-oxo-2,3-diphenylmorpholine 112741-50-1 500mg $140 2021-12-16 Buy
TRC B699835 (2S,3R)-(+)-N-Boc-6-oxo-2,3-diphenylmorpholine 112741-50-1 2.5g $360 2021-12-16 Buy
Biosynth Carbosynth FB63306 (2S,3R)-tert-Butyl 6-oxo-2,3-diphenylmorpholine-4-carboxylate 112741-50-1 5G $825 2021-12-16 Buy
Product number Packaging Price Buy
331813 5g $441 Buy
331813 1g $97.8 Buy
B699835 500mg $140 Buy
B699835 2.5g $360 Buy
FB63306 5G $825 Buy

tert-Butyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Chemical Properties,Uses,Production

Uses

(2S,3R)-(+)-N-Boc-6-oxo-2,3-diphenylmorpholine (Williams chiral auxiliary) can be used as a reactant:

  • In the asymmetric synthesis of cylindrospermopsin and related alkaloids via an intramolecular 1,3-dipolar cycloaddition reaction.
  • To synthesize boc-3-(1-methylcyclopropyl)-D-alanine, which is used as an intermediate to prepare 4-fluoroproline-based analogs as potent tripeptide thrombin inhibitors.
  • In the total synthesis of potent hepatotoxic alkaloid 7-epicylindrospermopsin by intramolecular 1,3-dipolar cycloaddition and nitroaldol reaction.
  • To prepare differentially functionalized diaminoglutamic acids via radical reaction of selenide with methyl 2-acetamidoacrylate.

tert-Butyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 116)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21149 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739 info@dycnchem.com CHINA 52867 58
Labnetwork lnc.
+86-27-50766799 +8618062016861 contact@labnetwork.com China 19994 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418684 +8618949823763 sales@tnjchem.com China 25363 58
SyncoZymes (Shanghai) Co., Ltd.,
+86-021-68187180-811 +86-13681683526 lchen@syncozymes.com China 188 58

View Lastest Price from tert-Butyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
tert-Butyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate pictures 2021-08-12 tert-Butyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate
112741-50-1
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
tert-Butyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate pictures 2020-01-05 tert-Butyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate
112741-50-1
US $9.80 / KG 1g ≥99% 100kg Career Henan Chemical Co
(2S,3R)-6-Oxo-2,3-diphenyl-morpholine-4-carboxylic acid tert-butyl ester (5S,6R)-(+)-4-Boc-5,6-diphenyl-2-Morpholinone, 99% (2S,3R)-(+)-N-Boc-6-oxo-2,3-diphenylMorpholine (5R,6S)-N-Boc-5,6-diphenyl-2-morpholinone tert-butyl (2S,3R)-6-oxo-2,3-diphenylMorpholine-4-carboxylate (2S,3R)-(+)-N-Boc-6-oxo-2,3-diphenylMorpholine (2S, 3R) - (+) - N- t-butoxycarbonyl-6-oxo-2,3-diphenyl-Morpholine (2S,3R)-6-Oxo-2,3-diphenyl-4-morpholinecarboxylic Acid 1,1-Dimethylethyl Ester (2S,3R)-6-oxo-2,3-diphenylmorpholine-4-carboxylate (2S,3R)-(+)-N-tert-Butoxycarbonyl-6-oxo-2,3-diphenylmorpholine (2S,3R)-6-Oxo-2,3-diphenyl-4-morpholinecarboxylic Acid tert-Butyl Ester,99%e.e. TERT-BUTYL (2S,3R)-(+)-6-OXO-2,3-DIPHENYL-4-MORPHOLINECARBOXYLATE N-TERT-BUTOXYCARBONYL-(2S,3R)-(+)-6-OXO-2,3-DIPHENYL-4-MORPHOLINE-CARBOXYLATE N-BOC(2S, 3R)-(+)-6-OXO-2,3-DIPHENYL-4-MORPHOLINE CARBOXYLATE (5R,6S)-4-TERT-BUTOXYCARBONYL-5,6-DIPHENYLMORPHOLIN-2-ONE tert-butyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morph TERT-BUTYL (2S,3R)-(+)-6-OXO-2,3-DIPHENY L-4-MORPHOLINECARBOXYLATE, 99% (99% EE) (2S,3R)-tert-Butyl 6-oxo-2,3- diphenylmorpholine-4-carboxylate (5S,6R)-4-tert-Butoxycarbonyl-5,6-diphenylmorpholin-2-one (2S,3R)-tert-Butyl 6-oxo-2,3-diphenylMorpholine-4-carboxylate (2S,3R)-6-Oxo-2,3-diphenyl-4-morpholinecarboxylic Acid tert-Butyl Ester 4-Morpholinecarboxylic acid, 6-oxo-2,3-diphenyl-, 1,1-dimethylethyl ester, (2S,3R)- 2S,3R-6-oxo-2,3-diphenyl-4-morpholinecarboxylate 112741-50-1 41-50-1 Morpholines Heterocyclic Building Blocks Asymmetric Synthesis Chiral Building Blocks Chiral Building Blocks Heterocyclic Building Blocks Morpholines API intermediates