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Isopropyl isocyanate

CAS No.
1795-48-8
Chemical Name:
Isopropyl isocyanate
Synonyms
2-Isocyanatopropane;i-pic;Isopropylisocyanat;2-PROPYLISOCYANATE;2-isocyanato-propan;Isorpopyl Isocyanate;ISOPROPYL ISOCYANATE;Propane,2-isocyanato-;IsopropylIsocyanate>ISORPOPYL ISOCYANATE 99%
CBNumber:
CB1249969
Molecular Formula:
C4H7NO
Molecular Weight:
85.1
MDL Number:
MFCD00002037
MOL File:
1795-48-8.mol
Last updated:2023-08-15 17:37:19

Isopropyl isocyanate Properties

Melting point <-75℃
Boiling point 74-75 °C(lit.)
Density 0.866 g/mL at 25 °C(lit.)
refractive index n20/D 1.382(lit.)
Flash point 27 °F
storage temp. 2-8°C
solubility Chloroform (Soluble), Ethyl Acetate
form Oil
color Colourless
Water Solubility Insoluble
Sensitive Moisture Sensitive
BRN 969356
Stability Hygroscopic, Light Sensitive, Moisture Sensitive, Volatile
CAS DataBase Reference 1795-48-8(CAS DataBase Reference)
EPA Substance Registry System Propane, 2-isocyanato- (1795-48-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS06,GHS08
Signal word  Danger
Hazard statements  H225-H315-H317-H319-H330-H334-H335
Precautionary statements  P210-P233-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
Hazard Codes  F,T+,Xi
Risk Statements  11-26-36/37/38-42
Safety Statements  16-23-26-36/37/39-45
RIDADR  UN 2483 3/PG 1
WGK Germany  1
10-21
TSCA  Y
HazardClass  3
PackingGroup  I
HS Code  29291090
NFPA 704
3
4 2
W

Isopropyl isocyanate price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 141070 Isopropyl isocyanate ≥98% 1795-48-8 1g $65.5 2024-03-01 Buy
Sigma-Aldrich 141070 Isopropyl isocyanate ≥98% 1795-48-8 25g $242 2024-03-01 Buy
Alfa Aesar L16105 Isopropyl isocyanate, 98+% 1795-48-8 1g $45 2024-03-01 Buy
TRC I872050 Isopropyl isocyanate 1795-48-8 5g $195 2021-12-16 Buy
Usbiological 280261 Isopropyl isocyanate 1795-48-8 1g $375 2021-12-16 Buy
Product number Packaging Price Buy
141070 1g $65.5 Buy
141070 25g $242 Buy
L16105 1g $45 Buy
I872050 5g $195 Buy
280261 1g $375 Buy

Isopropyl isocyanate Chemical Properties,Uses,Production

Chemical Properties

Colorless liquid

Uses

Isopropyl isocyanate is used as a reagent in the preparation of androgen receptor antagonist for prostate cancer treatment. It is also used in the synthesis of selective dual inhibitor of mammalian target of rapamycin (mTORC1 and mTORC2). Further, it serves as a reagent in the synthesis of O-aryl N-isopropylcarbamates. In addition to this, it is used as a derivatization reagent during the stereoisomeric analysis of secondary alcohols.

General Description

A colorless liquid with a pungent odor. Insoluble in water. Flash point near 60°F. Very toxic by ingestion and inhalation. Vapors are heavier than air. Used to make other chemicals.

Air & Water Reactions

Highly flammable. Insoluble in water.

Reactivity Profile

Isocyanates and thioisocyanates, such as Isopropyl isocyanate, are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Acids and bases initiate polymerization reactions in these materials. Some isocyanates react with water to form amines and liberate carbon dioxide. Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. Such reactions in the absence of solvents often occur with explosive violence, [Wischmeyer(1969)].

Health Hazard

TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Bromoacetates and chloroacetates are extremely irritating/lachrymators. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.

38955-43-0
1795-48-8
Synthesis of Isopropyl isocyanate from N-(propan-2-yl)carbamoyl chloride

Isopropyl isocyanate Preparation Products And Raw materials

Global( 199)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12452 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15371 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8822 58
Xiamen AmoyChem Co., Ltd
+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
Shandong chuangyingchemical Co., Ltd.
18853181302 sale@chuangyingchem.com CHINA 5909 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58

View Lastest Price from Isopropyl isocyanate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Isopropyl isocyanate pictures 2023-08-15 Isopropyl isocyanate
1795-48-8
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
Isopropyl isocyanate pictures 2022-10-15 Isopropyl isocyanate
1795-48-8
US $200.00 / TON 100TON 99% 600 Molokomalapatrading Ltd.
Isopropyl isocyanate pictures 2021-11-16 Isopropyl isocyanate
1795-48-8
US $10.00 / KG 1KG 99% 5tons Hebei Guanlang Biotechnology Co., Ltd.
ISOCYANIC ACID ISOPROPYL ESTER ISOPROPYL ISOCYANATE 2-isocyanato-propan i-pic propylisocyanate(non-specificname) --- D/C 09 --- Isopropyl isocyanate 100mg [1795-48-8] Isorpopyl Isocyanate ISOPROPYL ISOCYANATE, 98+% ISORPOPYL ISOCYANATE 99+% ISORPOPYL ISOCYANATE 99% Isopropylisocyanat 2-PROPYLISOCYANATE Propane,2-isocyanato- Isopropyl Isocyanate, 97+% IsopropylIsocyanate> 2-Isocyanatopropane 1795-48-8 1795-48-4 17895-48-8 CH32CHNCO Building Blocks Organic Building Blocks Nitrogen Compounds Isocyanates Isocyanates Nitrogen Compounds Organic Building Blocks