2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate
- CAS No.
- 164162-36-1
- Chemical Name:
- 2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate
- Synonyms
- Everolimus Impurity 12;Everolimus intermediate A2(Z);2-(tert-Butydilethylsily) oxyethyl;2-(t-ButyldiMethylsilyl)oxyethyl triflate;2-(tert-Butyldimethylsilyloxy)ethyl triflate;2-(t-Butyldimethylsilyloxy)EthylTrifluoromethanesulfonate;2-(tert-butyldiMethylsilyloxy)ethyl trifluoroMethanesulfonate;2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate;2-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}ethyl trifluoromethanesulfonate;Trifluoromethanesulfonic acid 2-[[(tert-butyl)dimethylsilyl]oxy]ethyl ester
- CBNumber:
- CB12542770
- Molecular Formula:
- C9H19F3O4SSi
- Molecular Weight:
- 308.39
- MDL Number:
- MFCD22572946
- MOL File:
- 164162-36-1.mol
- MSDS File:
- SDS
2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | ORS0003977 | 2-((TERT-BUTYLDIMETHYLSILYL)OXY)ETHYL TRIFLUOROMETHANESULFONATE 95.00% | 164162-36-1 | 5MG | $499.02 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | ORS0003977 | 2-((TERT-BUTYLDIMETHYLSILYL)OXY)ETHYL TRIFLUOROMETHANESULFONATE 95.00% | 164162-36-1 | 250MG | $1145.55 | 2021-12-16 | Buy |
2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate Chemical Properties,Uses,Production
Uses
2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate is used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthesis
The reaction was carried out under a nitrogen atmosphere. TBS- ethylene glycol prepared as per step 1 (85.10g, 0.48 mol) and 2, 6-Lutidine (84.28ml, 0.72 mol) were stirred in n-heptane (425ml) to give a clear solution which was then cooled to -15 to - 25°C. Trifluoromethanesulfonic anhydride (Tf2O) (99.74 ml, 0.590 mol) was added drop-wise over a period of 45 minutes to the n-heptane solution (white precipitate starts to form immediately) while maintaining the reaction at -15 to -25°C. The reaction mixture was kept at temperature between -15 to -25°C for 2 hours. The precipitate generated was filtered off. The filtrate was then evaporated up to ~2 volumes with respect to TBS-ethyiene glycol (~200 ml).
2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15932 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9641 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
| Nanjing Fred Technology Co., Ltd | +86-25-84696168 +86-15380713688 | Austin@fredbio.com | China | 2449 | 58 |