1,1,3,3-Tetramethylurea
- CAS No.
- 632-22-4
- Chemical Name:
- 1,1,3,3-Tetramethylurea
- Synonyms
- TMU;TETRAMETHYLUREA;Urea, tetramethyl-;Temur;tetramethyl-ure;1,1,3,3-tetramethyl-ure;NSC 91488;((CH3)2N)2CO;TERAMETHYLUREA;Four Methylurea
- CBNumber:
- CB1309805
- Molecular Formula:
- C5H12N2O
- Molecular Weight:
- 116.16
- MDL Number:
- MFCD00008319
- MOL File:
- 632-22-4.mol
- MSDS File:
- SDS
| Melting point | −1 °C(lit.) |
|---|---|
| Boiling point | 177 °C(lit.) |
| Density | 0.968 g/mL at 20 °C(lit.) |
| refractive index |
n |
| Flash point | 150 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Miscible with water, petroleum ether and common solvents. |
| form | Liquid |
| pka | 2.0(at 25℃) |
| color | Clear colorless to pale yellow |
| PH | 5-8 (25℃, 1M in H2O) |
| Relative polarity | 5 |
| Odor | faint pleasant odor |
| Water Solubility | H2O: 1 M at 20 °C, miscible |
| Merck | 14,9230 |
| BRN | 773898 |
| Dielectric constant | 24.460000000000001 |
| InChIKey | AVQQQNCBBIEMEU-UHFFFAOYSA-N |
| CAS DataBase Reference | 632-22-4(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 2O1EJ64031 |
| NIST Chemistry Reference | Urea, tetramethyl-(632-22-4) |
| EPA Substance Registry System | Tetramethylurea (632-22-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H318-H360D | |||||||||
| Precautionary statements | P202-P280-P301+P312-P302+P352-P305+P351+P338-P308+P313 | |||||||||
| Hazard Codes | Xn,T | |||||||||
| Risk Statements | 22-61 | |||||||||
| Safety Statements | 53-45 | |||||||||
| RIDADR | NA 1993 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | YU2625000 | |||||||||
| F | 3-10 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29241900 | |||||||||
| Toxicity | LD50 i.v. in rats: 1.1 g/kg (Lüttringhaus, Dirksen) | |||||||||
| NFPA 704 |
|
1,1,3,3-Tetramethylurea price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T24503 | Tetramethylurea 99% | 632-22-4 | 5g | $29 | 2024-03-01 | Buy |
| TCI Chemical | T0158 | Tetramethylurea >98.0%(GC) | 632-22-4 | 25g | $26 | 2024-03-01 | Buy |
| TCI Chemical | T0158 | Tetramethylurea >98.0%(GC) | 632-22-4 | 500g | $191 | 2024-03-01 | Buy |
| Alfa Aesar | A16295 | Tetramethylurea 99% | 632-22-4 | 50g | $42.8 | 2024-03-01 | Buy |
| Alfa Aesar | A16295 | Tetramethylurea 99% | 632-22-4 | 250g | $147 | 2024-03-01 | Buy |
1,1,3,3-Tetramethylurea Chemical Properties,Uses,Production
Chemical Properties
Tetramethylurea is a clear colorless to pale yellow liquid with mild aromatic odor that is miscible with water and many organic solvents. Unusual for an urea is the liquid state of tetramethylurea in a range of > 170 °C.
Uses
Tetramethylurea is used as a solvent in dyestuff industries, in condensation reaction and intermediates in surfactant. It is utilized for base catalyzed isomerization and alkylation hydrocyanation due to its low permittivity. It reacts with oxalyl chloride to prepare tetramethyl chloroformamidinium chloride, which is used for the conversion of carboxylic acids and dialkyl phosphates to anhydrides and pyrophosphates respectively.
Definition
ChEBI: 1,1,3,3-tetramethylurea is a member of the class of ureas that is urea substituted by methyl groups at positions 1, 1, 3 and 3 respectively. Metabolite observed in cancer metabolism. It has a role as a human metabolite.
Preparation
The reaction of dimethylamine with phosgene in the presence of e. g. 50 % sodium hydroxide solution and subsequent extraction with 1,2-dichloroethane yields tetramethylurea in 95% yield.
Safety Profile
Moderately toxic by ingestion and intravenous routes. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. Combustible when exposed to heat, flame, and oxidizers. To fight fire, use foam, mist, spray, dry chemicals. When heated to decomposition it emits toxic fumes of NOx.
Purification Methods
Dry it over BaO and distil it under nitrogen. It denatures proteins in H2O. [Elbaum & Herskovits Biochemistry 13 1268 1974, Kane Anal Biochem 53 350 1973, Beilstein 4 IV 225.]
1,1,3,3-Tetramethylurea Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15928 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10248 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 6992 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8823 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
Related articles
- The uses and toxicity of 1,1,3,3-Tetramethylurea
- 1,1,3,3-tetramethylurea is a colorless liquid used as a solvent in industrial applications. It has been shown to have slight a....
- Dec 8，2023
View Lastest Price from 1,1,3,3-Tetramethylurea manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-08-15 | 1,1,3,3-Tetramethylurea
632-22-4
|
US $0.00 / KG | 1KG | 99% | 20tons | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-05-24 | Tetramethylurea
632-22-4
|
US $18.90 / KG | 1000KG | 99.5 | 200000 | Chongqing Hesheng Longgang Technology Co. Ltd. | |
 |
2023-04-04 | 1,1,3,3-Tetramethylurea
632-22-4
|
US $56.00 / kg | 1kg | 99% | 5000 tons | Hebei Duling International Trade Co. LTD |
-
- 1,1,3,3-Tetramethylurea
632-22-4
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- Tetramethylurea
632-22-4
- US $18.90 / KG
- 99.5
- Chongqing Hesheng Longgang Technology Co. Ltd.
-
- 1,1,3,3-Tetramethylurea
632-22-4
- US $56.00 / kg
- 99%
- Hebei Duling International Trade Co. LTD
632-22-4(1,1,3,3-Tetramethylurea)Related Search:
1of4