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4-Chloroanisole

4-Chloroanisole structure

CAS No.: 623-12-1

Chemical Name:: 4-Chloroanisole

Synonyms: 1-CHLORO-4-METHOXYBENZENE;P-CHLOROANISOLE;para-Chloroanisole;4-Methoxyphenyl chloride;4-Chloroanisol;p-chloroanisol;Chloro anisole;4-CHLOROANISOLE;3 4-Chloroanisole;Anisole, p-chloro-

CBNumber:: CB1312283

Molecular Formula:: C7H7ClO

Molecular Weight:: 142.58

MDL Number:: MFCD00000616

MOL File:: 623-12-1.mol

MSDS File:: SDS

Last updated:2023-09-07 18:57:57

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4-Chloroanisole Properties

Melting point	?18 °C (lit.)
Boiling point	198-202 °C (lit.)
Density	1.164 g/mL at 25 °C (lit.)
vapor pressure	1.08hPa at 25℃
refractive index	n20/D 1.535(lit.)
Flash point	173 °F
storage temp.	Sealed in dry,Room Temperature
form	Liquid
color	Clear colorless to yellow
Water Solubility	immiscible
BRN	1858901
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.
LogP	2.78 at 25℃
CAS DataBase Reference	623-12-1(CAS DataBase Reference)
FDA UNII	0F18BLY08Q
NIST Chemistry Reference	Benzene, 1-chloro-4-methoxy-(623-12-1)
EPA Substance Registry System	Benzene, 1-chloro-4-methoxy- (623-12-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H227

Precautionary statements

P210e-P280a-P370+P378a-P501a-P210-P280-P403+P235-P501

Hazard Codes

Safety Statements

23-24/25

RIDADR

UN 2810

WGK Germany

TSCA

Yes

HS Code

29093090

NFPA 704

	2
1		0

4-Chloroanisole price More Price(29)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	159069	4-Chloroanisole 99%	623-12-1	25g	$102	2024-03-01	Buy
Sigma-Aldrich	159069	4-Chloroanisole 99%	623-12-1	100g	$286	2023-06-20	Buy
TCI Chemical	C0122	4-Chloroanisole >98.0%(GC)	623-12-1	25g	$44	2024-03-01	Buy
TCI Chemical	C0122	4-Chloroanisole >98.0%(GC)	623-12-1	500g	$252	2024-03-01	Buy
Alfa Aesar	A11377	4-Chloroanisole, 99%	623-12-1	50g	$57.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
159069	25g	$102	Buy
159069	100g	$286	Buy
C0122	25g	$44	Buy
C0122	500g	$252	Buy
A11377	50g	$57.65	Buy

4-Chloroanisole Chemical Properties,Uses,Production

Chemical Properties

colourless liquid

Uses

4-Chloroanisole was found to react with Cu (II)-smectite forming a blue clay-organic complex. 4-Chloroanisole was chosen as the main test substrate for the optimisation studies as it is electronically deactivated and thus resistant to oxidative addition and consequently very reluctant to enter a catalytic manifold.

Synthesis Reference(s)

Chemistry Letters, 16, p. 1901, 1987
The Journal of Organic Chemistry, 35, p. 528, 1970 DOI: 10.1021/jo00827a060

General Description

4-Chloroanisole is an electron-rich chloroarene. It undergoes Ullmann-type homocoupling catalyzed by in situ generated Pd colloids. Reaction of 4-chloroanisole with Cu(II)-smectite in n-hexane, carbon tetrachloride or dichloromethane has been studied. The nucleophilic photosubstitution reactions, photocyanation and photohydrolysis of 4-chloroanisole has been studied by time resolved spectroscopy.

Purification Methods

Wash the anisole with 10% (by volume) aqueous H2SO4 (three times), 10% aqueous KOH (three times), and then with water until neutral. Dry it (MgSO4), and fractionally distil it from CaH2 through a glass helices-packed column under reduced pressure. [Beilstein 16 IV 822.]

4-Chloroanisole Preparation Products And Raw materials

Raw materials

Disulfur dichloride o-Cresol 2,6-DICHLORO-1,4-BENZOQUINONE

Preparation Products

Ethyl 4-methoxycinnamate 4,4'-DIMETHOXYDIPHENYLAMINE 1-(4-Methoxyphenyl)-1-penten-3-one (4-METHOXYPHENYLETHYNYL)TRIMETHYLSILANE& 2-CHLORO-5-METHOXYBENZONITRILE

1-(4-METHOXYPHENYL)-1H-IMIDAZOLE Benzenamine, 4-methoxy-N,N-bis(4-methoxyphenyl)- 4-CHLORO-2-FLUOROANISOLE ETHYL 4-METHOXYPHENYLACETATE 2-(4-Methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane

4-Methoxybiphenyl

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4-Chloroanisole Suppliers

Global( 329)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8823	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
Richest Group Ltd	18017061086	oled@richest-group.com	CHINA	5601	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Hebei Guanlang Biotechnology Co., Ltd.	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Richest Group Ltd	58

View Lastest Price from 4-Chloroanisole manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-09-07	4-Chloroanisole 623-12-1	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd
2023-04-25	4-Chloroanisole 623-12-1	US $65.00 / kg	1kg	99%	5000 tons	Hebei Duling International Trade Co. LTD
2023-03-06	4-Chloroanisole 623-12-1	US $10.00 / KG	1KG	99%	10 ton	Hebei Guanlang Biotechnology Co,.LTD

4-Chloroanisole
623-12-1
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

4-Chloroanisole
623-12-1
US $65.00 / kg
99%
Hebei Duling International Trade Co. LTD

4-Chloroanisole
623-12-1
US $10.00 / KG
99%
Hebei Guanlang Biotechnology Co,.LTD

4-Chloroanisole Spectrum

4-Chloroanisole(623-12-1)MS 4-Chloroanisole(623-12-1)¹HNMR 4-Chloroanisole(623-12-1)¹³CNMR 4-Chloroanisole(623-12-1)IR1 4-Chloroanisole(623-12-1)Raman

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1-chloro-4-methoxy-benzen 4-Chloroanisol 4-Chlorophenol methyl ether Anisole, p-chloro- Benzene,1-chloro-4-methoxy- p-chloroanisol p-Chloromethoxybenzene p-Chlorophenyl methyl ether 4-CHLOROANISOLE Chloro anisole 4-chloroMethyl ether 3 4-Chloroanisole 4-Chlorophenyl methyl ether 4-CHLOROANISOLE PESTANAL 4-Chloroanisole,98% 2-methyl-4-chloro phenol，4-chloro anisole Methyl(4-chlorophenyl) ether 4-Chloroanisole,99% 4-Chloroanisole > para-Chloroanisole 1-CHLORO-4-METHOXYBENZENE P-CHLOROANISOLE 4-Methoxyphenyl chloride 2,4-Dichlorobenzyl Alcohol Impurity 62 623-12-1 623-12-7 632-12-1 Ethers Building Blocks Oxygen Compounds Organic Building Blocks Aromatic Ethers Anisoles, Alkyloxy Compounds & Phenylacetates Chlorine Compounds Ethers Organic Building Blocks Oxygen Compounds 623-12-1