Azido-dPEG4-acid
- CAS No.
- 1056024-94-2
- Chemical Name:
- Azido-dPEG4-acid
- Synonyms
- 3-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)propanoic acid;N3-PEG3-COOH;Azido-dPEG4-acid;N3-PEG3-CH2CH2COOH;Azido-PEG3-CH2CH2COOH;N3-PEG3-COOH,Azido-PEG3-acid;N3-(CH2)2-O-(CH2-CH2-O)2-(CH2)2-COOH;3-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)propanoicacid/N3-PEG3-CH2CH2COOH;N3-PEG3-CH2CH2COOH/Propanoic acid, 3-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-
- CBNumber:
- CB13146560
- Molecular Formula:
- C9H17N3O5
- Molecular Weight:
- 247.25
- MDL Number:
- MFCD23726617
- MOL File:
- 1056024-94-2.mol
- MSDS File:
- SDS
Azido-dPEG4-acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | A965575 | Azido-peg3Acid | 1056024-94-2 | 50mg | $155 | 2021-12-16 | Buy |
| TRC | A965575 | Azido-peg3Acid | 1056024-94-2 | 100mg | $240 | 2021-12-16 | Buy |
| Apolloscientific | BIPG1105 | Azido-PEG3-acid | 1056024-94-2 | 500mg | $378 | 2021-12-16 | Buy |
| AK Scientific | AMTGC715 | 3-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]propanoicacid | 1056024-94-2 | 250mg | $160 | 2021-12-16 | Buy |
| BroadPharm | BP-21583 | Azido-PEG3-acid 98% | 1056024-94-2 | 250mg | $160 | 2021-12-16 | Buy |
Azido-dPEG4-acid Chemical Properties,Uses,Production
Description
Azido-PEG3-acid is a crosslinker containing an azide(N3) group with a carboxylic acid (CO2H). The terminal carboxylic acid is reactive with primary amine groups in the presence of activators (e.g. EDC, or HATU) forming a stable amide bond. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.
Definition
ChEBI: 3-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}propanoic acid is an organonitrogen compound.
Biological Activity
Azido-dPEG4-acid is a PEG-based PROTAC linker for the synthesis of BI-3663 (HY-111546), BI-4216 and BI-0319. It is also a non-cleavable ADC linker containing 3-unit PEG, which can be used to synthesize antibody drug conjugates (ADC).
in vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
target
| PEGs
| Non-cleavable
|
Azido-dPEG4-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Azido-dPEG4-acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Chengdu Pukang Biotechnology Co., Ltd | 028-82550498 | export@pu-kang.com | CHINA | 210 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 6710 | 58 |
| Shaanxi Youbang Biopharma Technology Co.,Ltd. | +86-0913-7167565 +8618754046789 | 316745545@qq.com | China | 86 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3149 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
View Lastest Price from Azido-dPEG4-acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-24 | azido-PEG3-Acid
1056024-94-2
|
US $0.00 / g | 10g | >98.00% | 10g | Xian confluore Biological Technology Co., Ltd. |
-
- azido-PEG3-Acid
1056024-94-2
- US $0.00 / g
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
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