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L-Leucyl-L-Leucine methyl ester (hydrochloride)

L-Leucyl-L-Leucine methyl ester (hydrochloride) structure

CAS No.: 6491-83-4

Chemical Name:: L-Leucyl-L-Leucine methyl ester (hydrochloride)

Synonyms: Leu-Leu-ome hydrochloride;H-Leu-leu-OMe hydrochloride;L-Leucyl-L-Leucine methyl ester;L-Leucyl-L-Leucine methyl ester (hydrochloride);L-Leucine, L-leucyl-, methyl ester, monohydrochloride;methyl (2S)-2-[(2S)-2-amino-4-methylpentanamido]-4-methylpentanoate hydrochloride;lymphocytes,leukocytes,monocytes,pathway,LLeucylLLeucine methyl ester hydrochloride,LLOMe,inhibit,polymorphonuclear,stress,Leu-Leu methyl ester,cytotoxic,Inhibitor,L Leucyl L Leucine methyl ester hydrochloride,Endogenous Metabolite,endolysosomal

CBNumber:: CB13152666

Molecular Formula:: C13H27ClN2O3

Molecular Weight:: 294.81808

MDL Number:: MFCD00155477

MOL File:: 6491-83-4.mol

MSDS File:: SDS

Last updated:2023-05-18 11:31:06

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L-Leucyl-L-Leucine methyl ester (hydrochloride) Properties

Melting point	177-181°C
storage temp.	Hygroscopic, Refrigerator, under inert atmosphere
solubility	DMSO (Slightly), Water (Slightly)
form	Solid
color	White to Off-White
Stability	Hygroscopic
FDA UNII	76R0TP2LNW

L-Leucyl-L-Leucine methyl ester (hydrochloride) price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	16008	L-Leucyl-L-Leucine methyl ester (hydrochloride) ≥95%	6491-83-4	100mg	$32	2024-03-01	Buy
Cayman Chemical	16008	L-Leucyl-L-Leucine methyl ester (hydrochloride) ≥95%	6491-83-4	1g	$78	2024-03-01	Buy
Cayman Chemical	16008	L-Leucyl-L-Leucine methyl ester (hydrochloride) ≥95%	6491-83-4	250mg	$53	2024-03-01	Buy
TRC	L330805	H-Leu-leu-OMehydrochloride	6491-83-4	1g	$50	2021-12-16	Buy
AK Scientific	0116CW	Methylleucylleucinatehydrochloride	6491-83-4	100mg	$133	2021-12-16	Buy

Product number	Packaging	Price	Buy
16008	100mg	$32	Buy
16008	1g	$78	Buy
16008	250mg	$53	Buy
L330805	1g	$50	Buy
0116CW	100mg	$133	Buy

L-Leucyl-L-Leucine methyl ester (hydrochloride) Chemical Properties,Uses,Production

Description

L-Leucyl-L-Leucine methyl ester (LLME) is a lysosomal condensation product that has been reported to be cytotoxic towards natural killer cells and CD4⁺ and CD8⁺ T lymphocytes without affecting helper T cells and B cells. It has also been shown to induce death of monocytes, polymorphonuclear leukocytes, and myeloid tumor cells. Upon entry into cells via receptor-mediated endocytosis, LLME undergoes a condensation process catalyzed by dipeptidyl peptidase I (DPPI) in lysosomes. This condensation leads to lysosomal rupture and DNA fragmentation in DPPI-expressing immune cells such as cytotoxic T cells and natural killer cells.

Uses

H-Leu-leu-OMe HCl

L-Leucyl-L-Leucine methyl ester (hydrochloride) Preparation Products And Raw materials

Raw materials

Preparation Products

L-Leucyl-L-Leucine methyl ester (hydrochloride) Suppliers

Global( 41)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
GL Biochem (Shanghai) Ltd.	+86-021-61263370 +86-18901917034		CHINA	3904	58
GL Biochem(Binhai) Ltd.	+86-021-61263370 +8615301650015	wuqiuyan@glschina.com	China	2975	58
BOC Sciences	+16314854226	inquiry@bocsci.com	United States	19743	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19915	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Shanghai GL Peptide Ltd.	+86-21-61263310; 13764994101 13764994101	fisherwang@glschina.com	China	8457	55
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58

Supplier	Advantage
GL Biochem (Shanghai) Ltd.	58
GL Biochem(Binhai) Ltd.	58
BOC Sciences	58
Nextpeptide Inc	58
TargetMol Chemicals Inc.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
LEAPCHEM CO., LTD.	58
Aladdin Scientific	58
Shanghai GL Peptide Ltd.	55
Shanghai EFE Biological Technology Co., Ltd.	58

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L-Leucyl-L-Leucine methyl ester (hydrochloride) methyl (2S)-2-[(2S)-2-amino-4-methylpentanamido]-4-methylpentanoate hydrochloride Leu-Leu-ome hydrochloride H-Leu-leu-OMe hydrochloride L-Leucine, L-leucyl-, methyl ester, monohydrochloride L-Leucyl-L-Leucine methyl ester lymphocytes,leukocytes,monocytes,pathway,LLeucylLLeucine methyl ester hydrochloride,LLOMe,inhibit,polymorphonuclear,stress,Leu-Leu methyl ester,cytotoxic,Inhibitor,L Leucyl L Leucine methyl ester hydrochloride,Endogenous Metabolite,endolysosomal 6491-83-4 C13H26N2O3ClH