Diclazuril
- CAS No.
- 101831-37-2
- Chemical Name:
- Diclazuril
- Synonyms
- Qiujia;Nuoqiu;Vecoxan;R-64433;CLINACOX;clinazox;iclazuril;DICLAZUTIL;DICLAZURIL;To g beads
- CBNumber:
- CB1317293
- Molecular Formula:
- C17H9Cl3N4O2
- Molecular Weight:
- 407.64
- MDL Number:
- MFCD00867203
- MOL File:
- 101831-37-2.mol
- MSDS File:
- SDS
Melting point | 290.5° |
---|---|
Density | 1.56±0.1 g/cm3(Predicted) |
storage temp. | Inert atmosphere,Room Temperature |
solubility | DMF: 5mg/mL; DMSO: 5mg/mL; DMSO:PBS (pH 7.2) (1:5): 0.16mg/mL |
pka | 5.89±0.20(Predicted) |
form | Solid |
color | White to Light yellow to Light orange |
Merck | 14,3080 |
InChI | InChI=1S/C17H9Cl3N4O2/c18-10-3-1-9(2-4-10)12(7-21)16-13(19)5-11(6-14(16)20)24-17(26)23-15(25)8-22-24/h1-6,8,12H,(H,23,25,26) |
InChIKey | ZSZFUDFOPOMEET-UHFFFAOYSA-N |
SMILES | C1(C=C(C(C(C#N)C2=CC=C(Cl)C=C2)=C(Cl)C=1)Cl)N1N=CC(=O)NC1=O |
LogP | 2.439 (est) |
CAS DataBase Reference | 101831-37-2(CAS DataBase Reference) |
FDA 21 CFR | 556.185; 558.205; 558.4 |
FDA UNII | K110K1B1VE |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS08 |
---|---|
Signal word | Warning |
Hazard statements | H361d-H373 |
Precautionary statements | P202-P260-P280-P308+P313-P405-P501 |
Safety Statements | 24/25 |
WGK Germany | 2 |
RTECS | CY1697600 |
HS Code | 29336990 |
Diclazuril price More Price(34)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 34057 | Diclazuril VETRANAL?, analytical standard | 101831-37-2 | 100mg | $113 | 2024-03-01 | Buy |
Sigma-Aldrich | 1188560 | Diclazuril United States Pharmacopeia (USP) Reference Standard | 101831-37-2 | 200mg | $436 | 2024-03-01 | Buy |
TCI Chemical | D5457 | Diclazuril >98.0%(HPLC)(T) | 101831-37-2 | 1g | $53 | 2024-03-01 | Buy |
TCI Chemical | D5457 | Diclazuril >98.0%(HPLC)(T) | 101831-37-2 | 5g | $262 | 2024-03-01 | Buy |
Cayman Chemical | 27047 | Diclazuril | 101831-37-2 | 5g | $68 | 2024-03-01 | Buy |
Diclazuril Chemical Properties,Uses,Production
Description
Diclazuril (molecular formula: C17H9Cl3N4O2, Trade name: Vecoxan) belongs to a kind of coccidiostat and potent antiprotozoal agents. It is mainly used for the treatment, control, prevention and improvements of Coccidal infections. It alleviates the symptoms of the patients by interrupting the life cycle of the parasites. It induces the morphological changes and attenuates the mitochondrial transmembrane potential in meroites. It can prevent congenital toxoplasmosis and have anticoccidial effects in vivo. It is active through oral administration.
References
http://www.tabletwise.com/medicine/diclazuril
https://en.wikipedia.org/wiki/Diclazuril
http://www.abcam.com/diclazuril-ab143604.html
Chemical Properties
Light yellow or off-white powder, almost insoluble in water, slightly soluble in ethanol, ether, soluble in N,N-2 methylformamide (DMF), dimethylsulfone (DMSO), tetrahydrofuran (THF).
Uses
Diclazuril is a triazinone antiprotozoal that Nucleotide analog with broad-spectrum anticoccidial activity. It has a control effect on a variety of coccidiosis, and is used to prevent coccidiosis in chickens, ducks, quails, turkeys, geese and rabbits.
Definition
ChEBI: 2-(4-chlorophenyl)-2-[2,6-dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenyl]acetonitrile is a nitrile.
Application
Diclazuril is a less toxic, orally administered triazine antiprotozoal. It is widely used in veterinary medicine as a feed additive and veterinary drug. It is registered for oral use in broilers and lambs. Its use in cats (one dose of 25 mg/kg BW) is off-label only. It may be used clinically for the treatment of bovine protozoa. It is also used for the treatment of equine protozoan spinal cord encephalitis (EPM) caused by neuronal sarcocysts.
Veterinary Drugs and Treatments
Diclazuril is a coccidiostat. It is indicated for the treatment of equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona and as a coccidiostat in broiler chickens. Diclazuril could potentially be useful in treating coccidiosis, Neospora caninum and Toxoplasma infections in dogs or cats.
Diclazuril Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei ZB Gamay Biological Technology Co.,Ltd | +8617330018573 | info@zbvet.net | China | 245 | 58 |
shandong perfect biotechnology co.ltd | +86-53169958659; +8618596095638 | sales@sdperfect.com | China | 294 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3878 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12446 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5882 | 58 |
Changzhou Rokechem Technology Co., Ltd. | 18758118018 | sales001@rokechem.com | China | 255 | 58 |
Anhui Yiao New Material Technology Co., Ltd | +86-18033737140 +86-17354101231 | sales1@hbganmiao.com | China | 253 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 1000 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
Related articles
- Diclazuril: Introduction;Administered;Mechanism of action
- Diclazuril is a less toxic, orally administered triazine antiprotozoal. It is widely used in veterinary medicine as a feed add....
- Dec 7,2023
View Lastest Price from Diclazuril manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-20 | Diclazuril
101831-37-2
|
US $6.00 / kg | 1kg | 99% | 2000KG/Month | HebeiShuoshengImportandExportco.,Ltd | ||
2024-09-19 | DICLAZURIL
101831-37-2
|
US $10.00 / KG | 1KG | 99.9% | 100000kg | Hebei Chuanghai Biotechnology Co,.LTD | ||
2024-09-18 | Diclazuril
101831-37-2
|
US $0.00-0.00 / Kg/Drum | 25KG | 96%min | 3500kg/month | WUHAN FORTUNA CHEMICAL CO., LTD |
- Diclazuril
101831-37-2
- US $6.00 / kg
- 99%
- HebeiShuoshengImportandExportco.,Ltd
- DICLAZURIL
101831-37-2
- US $10.00 / KG
- 99.9%
- Hebei Chuanghai Biotechnology Co,.LTD
- Diclazuril
101831-37-2
- US $0.00-0.00 / Kg/Drum
- 96%min
- WUHAN FORTUNA CHEMICAL CO., LTD