4-Amino-3-methylphenol
- CAS No.
- 2835-99-6
- Chemical Name:
- 4-Amino-3-methylphenol
- Synonyms
- 4-AMINO-3-METHYLPHENOL;4-AMINO-3-CRESOL;Phenol, 4-amino-3-methyl-;p-Hydroxy-o-toluidine;3-Methyl-4-aminophenol;JAROCOL 4A3MP;4-amino-meta-;Amino-M-Cresol;4-amino-cresol;4-amino-m-creso
- CBNumber:
- CB1365623
- Molecular Formula:
- C7H9NO
- Molecular Weight:
- 123.15
- MDL Number:
- MFCD00007871
- MOL File:
- 2835-99-6.mol
- MSDS File:
- SDS
Melting point | 176-179 °C (lit.) |
---|---|
Boiling point | 229.26°C (rough estimate) |
Density | 1.0877 (rough estimate) |
refractive index | 1.5380 (estimate) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | soluble in Methanol |
form | Powder |
pka | 10.34±0.18(Predicted) |
color | Brown |
Water Solubility | insoluble |
BRN | 2078803 |
InChIKey | QGNGOGOOPUYKMC-UHFFFAOYSA-N |
LogP | 0.51 at 22℃ |
CAS DataBase Reference | 2835-99-6(CAS DataBase Reference) |
EWG's Food Scores | 3-6 |
FDA UNII | 12R07I1K8C |
NIST Chemistry Reference | 4-Amino-3-methyl phenol(2835-99-6) |
EPA Substance Registry System | Phenol, 4-amino-3-methyl- (2835-99-6) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07,GHS09 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H400 | |||||||||
Precautionary statements | P273-P301+P312+P330-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 22-36/37/38-20/21/22 | |||||||||
Safety Statements | 26-37/39-36/37/39-36-24/25 | |||||||||
RIDADR | UN3077 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | GO6826000 | |||||||||
F | 8-10-23 | |||||||||
TSCA | Yes | |||||||||
HazardClass | 9 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29222900 | |||||||||
NFPA 704 |
|
4-Amino-3-methylphenol price More Price(28)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 144894 | 4-Amino-3-methylphenol 97% | 2835-99-6 | 5g | $44.4 | 2024-03-01 | Buy |
Sigma-Aldrich | 144894 | 4-Amino-3-methylphenol 97% | 2835-99-6 | 25g | $155 | 2024-03-01 | Buy |
TCI Chemical | A0288 | 4-Amino-m-cresol >98.0%(GC)(T) | 2835-99-6 | 25g | $58 | 2024-03-01 | Buy |
Alfa Aesar | B23152 | 4-Amino-3-methylphenol, 98% | 2835-99-6 | 100g | $157.65 | 2024-03-01 | Buy |
TRC | A898190 | 4-Amino-3-methylphenol | 2835-99-6 | 50g | $75 | 2021-12-16 | Buy |
4-Amino-3-methylphenol Chemical Properties,Uses,Production
Description
4-Amino-3-methylphenol is a metabolite of 3-methyl-4-nitrophenol. It is a major metabolite of carcinogenic o-toluidine and causes DNA damage in the presence of Cu(II).
Chemical Properties
Light gray powder
Uses
4-Amino-3-methylphenol is a useful reagent for the synthesis of piperidine (piperazine)-amide substituted derivatives as multi-target antipsychotics.
4-Amino-3-methylphenol was used in synthesis of a new type of tweezer-molecule in which a strongly preferred binding conformation is generated by convergent, intramolecular hydrogen bonding.
Definition
ChEBI: A substituted aniline in which the aniline ring carries 4-hydroxy and 6-methyl substituents; a urinary metabolite of lidocaine.
Application
4-Amino-m-cresol is used as an oxidative hair dye at a maximum concentration of 1.5% after mixing with peroxide.
General Description
4-Amino-3-methylphenol is a metabolite of 3-methyl-4-nitrophenol. It is a major metabolite of carcinogenic o-toluidine and causes DNA damage in the presence of Cu(II).
Flammability and Explosibility
Not classified
Synthesis
The synthesis of 4-Amino-3-methylphenol is as follows:A mixture of the para-benzoquinone mono-oxime (1.26 mmol),SnCl2 (0.72 g, 3.80 mmol), 20 mL of CH2Cl2, and 0.2 mL of concentrated HCl, was heated to reflux for 16 h. The CH2Cl2 was removed under reduced pressure, and the residue was dissolved in ethyl acetate and washed with concentrated aqueous NaHCO3. The organic layer was dried over anhydrous Na2SO4 and the filtrate was concentrated under reduced pressure to afford the solid product.
Purification Methods
Crystallise it from 50% EtOH. [Beilstein 13 H 593, 13 IV 1698.]
4-Amino-3-methylphenol Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Taixing Foreign Trade Nanjing Co., Ltd. | +8613182976929 | sales@tx-chem.com | China | 120 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 14764 | 58 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 7836 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8823 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5909 | 58 |
View Lastest Price from 4-Amino-3-methylphenol manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2023-12-26 | 4-Amino-3-methylphenol
2835-99-6
|
US $0.00 / kg | 1kg | 99% | 1000000 | Hebei Jingbo New Material Technology Co., Ltd | ||
2023-08-16 | 4-Amino-3-methylphenol
2835-99-6
|
US $20.00 / KG | 1KG | >99% | 50000kg/Month | Weijer International Trade (Hebei) Co., Ltd | ||
2023-06-03 | 4-Amino-3-methylphenol
2835-99-6
|
US $0.00-0.00 / kg | 1kg | 99% | 500000kg | Hebei Yibangte Import and Export Co. , Ltd. |
- 4-Amino-3-methylphenol
2835-99-6
- US $0.00 / kg
- 99%
- Hebei Jingbo New Material Technology Co., Ltd
- 4-Amino-3-methylphenol
2835-99-6
- US $20.00 / KG
- >99%
- Weijer International Trade (Hebei) Co., Ltd
- 4-Amino-3-methylphenol
2835-99-6
- US $0.00-0.00 / kg
- 99%
- Hebei Yibangte Import and Export Co. , Ltd.
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