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Cinobufotalin

CAS No.
1108-68-5
Chemical Name:
Cinobufotalin
Synonyms
Nsc90326;Cinobufotlin;CINOBUFOTALIN;Chinbufotalin;CINOBUFOTALIN(RG);Cinobufotalin std.;Cinobufotalin Standard;Cinobufotalin USP/EP/BP;cinobufotalin venom toad;5beta-Hydroxycinobufagin
CBNumber:
CB1410581
Molecular Formula:
C26H34O7
Molecular Weight:
458.54
MDL Number:
MFCD28396383
MOL File:
1108-68-5.mol
Last updated:2023-06-08 09:02:45

Cinobufotalin Properties

Melting point 259-262°
alpha D20 +11°
Boiling point 627.3±55.0 °C(Predicted)
Density 1.34±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMF: 10 mg/ml; DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml; DMSO: 5 mg/ml; Ethanol: 5 mg/ml
form White to off-white solid.
pka 14.67±0.70(Predicted)
CAS DataBase Reference 1108-68-5
FDA UNII L0QBZ37386
NCI Drug Dictionary cinobufotalin

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H300+H310+H330
Precautionary statements  P260-P262-P264-P280-P302+P352+P310-P304+P340+P310
Hazard Codes  T+
Risk Statements  26/27/28
Safety Statements  22-36/37/39-45
RIDADR  UN 2811 6.1/PG 1
WGK Germany  3
RTECS  EI2991000
HazardClass  6.1(a)
PackingGroup  II
Toxicity cat,LD50,intravenous,200ug/kg (0.2mg/kg),"Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963Vol. -, Pg. 189, 1963.
NFPA 704
0
4 0

Cinobufotalin price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C1147 Cinobufotalin 1108-68-5 10mg $416 2024-03-01 Buy
Cayman Chemical 19845 Cinobufotalin 1108-68-5 5mg $112 2024-03-01 Buy
Cayman Chemical 19845 Cinobufotalin 1108-68-5 25mg $341 2024-03-01 Buy
Cayman Chemical 19845 Cinobufotalin 1108-68-5 1mg $36 2024-03-01 Buy
Cayman Chemical 19845 Cinobufotalin 1108-68-5 10mg $172 2024-03-01 Buy
Product number Packaging Price Buy
C1147 10mg $416 Buy
19845 5mg $112 Buy
19845 25mg $341 Buy
19845 1mg $36 Buy
19845 10mg $172 Buy

Cinobufotalin Chemical Properties,Uses,Production

Description

Cinobufacin is an indole-type total alkaloid extracted from the dried toad skin of Chinese toad, which has the functions of clearing away heat and detoxifying, reducing swelling and pain, promoting blood circulation and removing blood stasis, softening and dispelling knots.

Application

Cinobufacin can be used for a variety of middle and advanced tumors (lung cancer, breast cancer, cervical cancer, digestive system tumors such as primary liver cancer, gastric cancer, colon cancer, etc.), chronic hepatitis B, especially for chronic hepatitis B virus carriers. Especially prominent.

Side effects

For individual patients, if the dosage is too large or the interval between two administrations is less than 6 to 8 hours, chills and fever may occur about 30 minutes after administration; a small number of patients have local irritation or phlebitis after long-term intravenous infusion, which will slow down the infusion rate. Very few patients may also appear urticaria, dermatitis and so on.

Cinobufotalin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 147)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3424 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Shaanxi Pioneer Biotech Co., Ltd .
+8613259417953 sales@pioneerbiotech.com China 3000 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Shanghai Standard Technology Co., Ltd.
18502101150 ft-sales@nature-standard.com CHINA 1923 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569266 15319487004 1015@dideu.com China 2263 58

View Lastest Price from Cinobufotalin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cinobufotalin pictures 2023-02-24 Cinobufotalin
1108-68-5
US $0.00 / mg 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
Cinobufotalin USP/EP/BP pictures 2021-07-05 Cinobufotalin USP/EP/BP
1108-68-5
US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited
Cinobufotalin pictures 2020-05-03 Cinobufotalin
1108-68-5
US $0.00-0.00 / Kg 1KG 99.0% 800 ton Shaanxi Dideu Medichem Co. Ltd
  • Cinobufotalin pictures
  • Cinobufotalin
    1108-68-5
  • US $0.00 / mg
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.
  • Cinobufotalin pictures
  • Cinobufotalin
    1108-68-5
  • US $0.00-0.00 / Kg
  • 99.0%
  • Shaanxi Dideu Medichem Co. Ltd
cinobufotalin venom toad Cinobufotalin std. 5BETA,20[22]-BUFADIENOLIDE-14,15BETA-EPOXY-3BETA,5ALPHA,16BETA-TRIOL 16-ACETATE 14,15-beta-epoxy-3-beta,5,16-beta-trihydroxy-22-dienolid16-5-beta-bufa-2 CINOBUFOTALIN(RG) 14,15b-Epoxy-3b,5a,16b-trihydroxy-5b,20(22)-bufadienolide 16-acetate 5β,20(22)-Bufadienolide-14,15β-epoxy-3β,5α,16β-triol 16-acetate, 14,15β-Epoxy-3β,5α,16β-trihydroxy-5β,20(22)-bufadienolide 16-acetate 14,15-Epoxy-14H-cyclopenta[a]phenanthrene, bufa-20,22-dienolide deriv. 5-b-Bufa-20,22-dienolide, 14,15-b-epoxy-3-b,5,16-b-trihydroxy, 16-acetate Bufa-20,22-dienolide, 16- (acetyloxy)-14,15-epoxy-3,5-dihydroxy-, (3.beta.,5.beta.,15.beta.,16.beta.)- 16β-(Acetyloxy)-14,15β-epoxy-3β,5-dihydroxy-5β,14β-bufa-20,22-dienolide 16β-Acetoxy-14,15β-epoxy-3β,5-dihydroxy-5β-bufa-20,22-dienolide 3β,5β-Dihydroxy-16β-acetoxy-14,15β-epoxy-5β-bufa-20,22-dienolide 5.beta.-Bufa-20,22-dienolide, 14,15.beta.-epoxy-3.beta.,5,16.beta.-trihydroxy-, 16-acetate Cinobufotlin Nsc90326 14,15β-Epoxy-3β,5α,16β-trihydroxy-5β,20(22)-bufadienolide 16-acetate 5β,20(22)-Bufadienolide-14,15β-epoxy-3β,5α,16β-triol 16-acetate CINOBUFOTALIN 20,22,5BETA-BUFADIENOLID-14BETA,15BETA-EPOXY-3BETA, 5BETA, 6BETA-TRIOL-16-ACETATE 14,15BETA-EPOXY-3BETA,5ALPHA,16BETA-TRIHYDROXY-5BETA,20[22]-BUFADIENOLIDE 16-ACETATE Cinobufotalin, 98%, from animal extracts 5beta-Hydroxycinobufagin, HPLC≥98% Cinobufotalin Standard Bufa-20,22-dienolide, 16-(acetyloxy)-14,15-epoxy-3,5-dihydroxy-, (3β,5β,15β,16β)- Cinobufotalin USP/EP/BP 5beta-Hydroxycinobufagin Chinbufotalin 1108-68-5 C26H34O7