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Dihydrocaffeic acid

Dihydrocaffeic acid structure

CAS No.: 1078-61-1

Chemical Name:: Dihydrocaffeic acid

Synonyms: NSC 407275;NSC 624007;Hydrocaffeate;HYDROCAFFEIC ACID;3-propionic acid;DIHYDROCAFFEIC ACID;DIHYDROCAFFEIC ACID(RG);3,4-DIHYDROCAFFEIC ACID;13C6]-Dihydrocaffeic acid;4-Dihydroxyhydrocinnamic acid

CBNumber:: CB1439090

Molecular Formula:: C9H10O4

Molecular Weight:: 182.17

MDL Number:: MFCD00002776

MOL File:: 1078-61-1.mol

MSDS File:: SDS

Last updated:2023-08-14 17:09:32

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Dihydrocaffeic acid Properties

Melting point	136-139 °C(lit.)
Boiling point	418℃
Density	1.398
Flash point	220℃
storage temp.	Inert atmosphere,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	4.75±0.10(Predicted)
color	Pale Beige to Pale Brown
Water Solubility	Slightly soluble in water.
BRN	2213449
InChI	InChI=1S/C9H10O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1,3,5,10-11H,2,4H2,(H,12,13)
InChIKey	DZAUWHJDUNRCTF-UHFFFAOYSA-N
SMILES	C1(CCC(O)=O)=CC=C(O)C(O)=C1
LogP	0.115 (est)
CAS DataBase Reference	1078-61-1(CAS DataBase Reference)
FDA UNII	MSW0228VUB

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

RTECS

MW5143500

NFPA 704

	0
2		0

Dihydrocaffeic acid price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	102601	3,4-Dihydroxyhydrocinnamic acid 98%	1078-61-1	2.5G	$55.56	2024-03-01	Buy
Sigma-Aldrich	102601	3,4-Dihydroxyhydrocinnamic acid 98%	1078-61-1	10G	$237	2024-03-01	Buy
Sigma-Aldrich	102601	3,4-Dihydroxyhydrocinnamic acid 98%	1078-61-1	25G	$463	2024-03-01	Buy
Alfa Aesar	A11638	3-(3,4-Dihydroxyphenyl)propionic acid, 98+%	1078-61-1	5g	$60.5	2024-03-01	Buy
Alfa Aesar	A11638	3-(3,4-Dihydroxyphenyl)propionic acid, 98+%	1078-61-1	25g	$186	2024-03-01	Buy

Product number	Packaging	Price	Buy
102601	2.5G	$55.56	Buy
102601	10G	$237	Buy
102601	25G	$463	Buy
A11638	5g	$60.5	Buy
A11638	25g	$186	Buy

Dihydrocaffeic acid Chemical Properties,Uses,Production

Description

Dihydrocaffeic acid is a polyphenol that has diverse biological activities, including antioxidant, neuroprotective, and enzyme inhibitory properties. Dihydrocaffeic acid scavenges ABTS (; IC₅₀ = 81.86 μg/ml) and 2,2-diphenyl-1-picrylhydrazyl (DPPH; ; IC₅₀ = 192.86 μg/ml) radicals and increases the survival of RGC-5 mouse retinal ganglion cells under hypoxic conditions and in the presence of S-nitroso-N-acetyl-D,L-penicillamine (SNAP; ) in a concentration-dependent manner. It also decreases endothelial nitric oxide synthase (eNOS) activity in EA.hy926 human endothelial cells in a concentration-dependent manner. In vivo, dihydrocaffeic acid (30 mg/kg) decreases infarct size in a rat model of transient ischemia induced by middle cerebral artery occlusion (MCAO).

Chemical Properties

Brown Solid

Uses

Dihydrocaffeic Acid is a natural product containing a catechol group with an α,β-unsaturated carboxylic acid chain. Dihydrocaffeic Acid has been shown to have hepatoprotective activity. Dihydrocaffei c Acid is a metabolite of Caffeic Acid (C08000) with potent antioxidant properties.

Uses

3-(3,4-Dihydroxyphenyl)propionic acid it can be used to produce 3-(3,4-dihydroxy-phenyl)-propionic acid octyl ester by heating.

Definition

ChEBI: A monocarboxylic acid that is 3-phenylpropionic acid substituted by hydroxy groups at positions 3 and 4. It is a metabolite of caffeic acid and exhibits antioxidant activity.

Dihydrocaffeic acid synthesis

Synthesis of Dihydrocaffeic acid from Caffeic acid

Dihydrocaffeic acid Preparation Products And Raw materials

Raw materials

Palladium hydroxide Triethyl phosphonoacetate tert-Butanol Tosylmethyl isocyanide Tetrahydrofuran

Ammonium chloride Ethyl acetate Protocatechualdehyde Magnesium sulfate Potassium

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Preparation Products

3,4-Dimethoxyhydrocinnamic acid 3-(2,2-dimethylbenzo[d][1,3]dioxol-6-yl)propanoic acid

Dihydrocaffeic acid Suppliers

Global( 225)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Jiangxi Chiyan Biopharmaceutical Technology Co.,Ltd.	+86-18616643091 +86-18616643091	info@rochipharma.com	China	246	58
Jiangsu Guiren Medicine Co.,Ltd	+86-13815020719 +86-13815020719	guiren_medicine@163.com	China	93	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12453	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15371	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2966	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8822	58

Supplier	Advantage
Jiangxi Chiyan Biopharmaceutical Technology Co.,Ltd.	58
Jiangsu Guiren Medicine Co.,Ltd	58
Hebei Mojin Biotechnology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Jinan Finer Chemical Co., Ltd	58
Hebei Guanlang Biotechnology Co., Ltd.	58

View Lastest Price from Dihydrocaffeic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-08-14	Dihydrocaffeic acid 1078-61-1	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd
2023-03-27	3-(3,4-DIHYDROXYPHENYL)PROPIONIC ACID 1078-61-1	US $25.00 / KG	1KG	0.99	20 tons	XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD
2023-03-06	Dihydrocaffeic acid 1078-61-1	US $10.00 / kg	1kg	99%	100000Ton	Hebei Guanlang Biotechnology Co,.LTD

Dihydrocaffeic acid
1078-61-1
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

3-(3,4-DIHYDROXYPHENYL)PROPIONIC ACID
1078-61-1
US $25.00 / KG
0.99
XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD

Dihydrocaffeic acid
1078-61-1
US $10.00 / kg
99%
Hebei Guanlang Biotechnology Co,.LTD

Dihydrocaffeic acid Spectrum

Dihydrocaffeic acid(1078-61-1)MS Dihydrocaffeic acid(1078-61-1)¹HNMR Dihydrocaffeic acid(1078-61-1)IR1 Dihydrocaffeic acid(1078-61-1)IR2

1078-61-1(Dihydrocaffeic acid)Related Search:

Methyldopa DL-DOPA 3-(3,4,5-TRIMETHOXYPHENYL)PROPIONIC ACID 3-(3,4-METHYLENEDIOXYPHENYL)PROPIONIC ACID 3-(4-HYDROXY-3-METHOXYPHENYL)PROPIONIC ACID

CINOXACIN Oxolinic acid (2S)-2-Amino-3-(3,4-dimethoxyphenyl)-2-methyl-propanoic acid 3,4-Dimethoxyhydrocinnamic acid Dihydrocaffeic acid

Levodopa (2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID BETANIN ETHYL 3-(3,4,5-TRIMETHOXYPHENYL)PROPIONATE (R)-2-Amino-3-(3,4-dihydroxyphenyl)propionic acid

DROXIDOPA DL-α-Hydrazino-α-methyl-β-(3,4-dihydroxyphenyl)propionic acid (R)-2-Hydroxy-3-(3,4-dihydroxyphenyl)propionic acid

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3-(3,4-Dihydroxyphenyl)propionic acid, Hydrocaffeic acid 3-(3,4-Dihydroxyphenyl)propionic acid, 98+% DIHYDROCAFFEIC ACID(RG) 3-(3,4-DIHYDROXYPHENYL)PROPIONIC ACID 3,4-DIHYDROXYHYDROCINNAMIC ACID 3,4-DIHYDROCAFFEIC ACID BETA-(3,4-DIHYDROXYPHENYL) PROPIONIC ACID DIHYDROCAFFEIC ACID HYDROCAFFEIC ACID 3,4-dihydroxy-benzenepropanoicaci 3,4-dihydroxybenzenepropanoicacid 3,4-dihydroxy-hydrocinnamicaci 3,4-Dihydroxyhydrocinnamic acid~Hydrocaffeic acid 3,4-dihydroxyphenylpropionic acid 3-(3,4-Dihydroxyphenyl)propanoic acid 3-propionic acid 3,4-Dihydroxybenzenepropionic Acid 3,4-DihydroxydihydrocinnaMic Acid NSC 407275 NSC 624007 3,4-Dihydroxy-beta-phenylpropionic acid 3-(3,4-dihydroxyphenyl)propanoate 4-Dihydroxyhydrocinnamic acid Benzenepropanoic acid, 3,4-dihydroxy- 3-(3,4-dihydroxyphenyl)propanoicaci 3-(3,4-DIHYDROXYPHENYL)PROPIONIC ACID USP/EP/BP 3- (3, 4-DIHYDROXYPHENYL) Propio Nic Acid / Dihydrocaffeic Acid Powder CAS 1078-61-1 13C6]-Dihydrocaffeic acid Hydrocaffeate 1078-61-1 HO2C6H3CH2CH2CO2H Carboxylic Acids Carbonyl Compounds C9 Building Blocks Organic Building Blocks Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals Aromatic Cinnamic Acids, Esters and Derivatives