ChemicalBook >> CAS DataBase List >>Hydroxyecdysone
Hydroxyecdysone
- CAS No.
- 5289-74-7
- Chemical Name:
- Hydroxyecdysone
- Synonyms
- ECDYSTERONE;20-HYDROXYECDYSONE;β-Ecdysterone;BETA-ECDYSTERONE;crustecdysone;ecdysteron;BETA-ECDYSONE;β-Ecdysone;B-ECDYSONE;the-7
- CBNumber:
- CB1692996
- Molecular Formula:
- C27H44O7
- Molecular Weight:
- 480.64
- MDL Number:
- MFCD00036740
- MOL File:
- 5289-74-7.mol
- MSDS File:
- SDS
Last updated:2024-04-23 19:22:53
| Melting point | 242-244 °C |
|---|---|
| Boiling point | 498.63°C (rough estimate) |
| Density | 1.0760 (rough estimate) |
| refractive index | 1.5800 (estimate) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | alcohol: soluble |
| form | powder |
| pka | 14.13±0.70(Predicted) |
| color | white |
| Merck | 13,3525 |
| BRN | 1917578 |
| InChIKey | NKDFYOWSKOHCCO-YPVLXUMRSA-N |
| SMILES | O[C@@]12CC[C@]([H])([C@](O)(C)[C@H](O)CCC(O)(C)C)[C@]1(CC[C@]1([H])[C@]3(C[C@H](O)[C@H](O)C[C@@]3([H])C(=O)C=C21)C)C |&1:1,4,6,9,17,20,22,24,26,29,r| |
| LogP | -0.270 (est) |
| CAS DataBase Reference | 5289-74-7(CAS DataBase Reference) |
| FDA UNII | 779A7KPL0Y |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H410 |
| Precautionary statements | P501-P273-P391 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 22-24/25-36-26 |
| WGK Germany | 2 |
| RTECS | FZ8060000 |
| F | 10 |
| HS Code | 29372900 |
Hydroxyecdysone price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H5142 | 20-Hydroxyecdysone ≥93% (HPLC), powder | 5289-74-7 | 5mg | $196 | 2024-03-01 | Buy |
| Sigma-Aldrich | H5142 | 20-Hydroxyecdysone ≥93% (HPLC), powder | 5289-74-7 | 10mg | $357 | 2024-03-01 | Buy |
| Alfa Aesar | J63091 | Ecdysterone | 5289-74-7 | 10mg | $213.65 | 2024-03-01 | Buy |
| Alfa Aesar | J63091 | Ecdysterone | 5289-74-7 | 50mg | $768.65 | 2024-03-01 | Buy |
| Cayman Chemical | 16145 | 20-hydroxy Ecdysone ≥98% | 5289-74-7 | 5mg | $49 | 2024-03-01 | Buy |
Hydroxyecdysone Chemical Properties,Uses,Production
Chemical Properties
White or off-white powder, odorless, hygroscopic, the color gradually becomes darker when exposed to light. Soluble in ethanol, slightly soluble in acetone, slightly soluble in hot water, ethyl acetate, chloroform, almost insoluble in ether, derived from Leulu, Achyranthes bidentata, Cyanotis, arachnoidea, Pfaffia glomerata.
Uses
20-Hydroxyecdysone has been used:
in Leibovitz′s dissecting medium for culturing sorting zone and neuropil-associated glia and antennal lobes of Manduca sexta
in Schneider′s medium to reproduce ex-vivo imaginal disc eversion
as a supplement in Mcl8 medium for culturing Drosophila wing imaginal discs
as an insect molting hormone
Definition
ChEBI: 20-hydroxyecdysone is an ecdysteroid that is ecdysone substituted by a hydroxy group at position 20. It has a role as a plant metabolite and an animal metabolite. It is a 20-hydroxy steroid, an ecdysteroid, a 14alpha-hydroxy steroid, a 3beta-sterol, a 2beta-hydroxy steroid, a 22-hydroxy steroid, a 25-hydroxy steroid and a phytoecdysteroid. It is functionally related to an ecdysone.
Biochem/physiol Actions
20-Hydroxyecdysone is an ecdysteroid hormone that plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene expression involved in molting and metamorphosis. It acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins (USP).
storage
+4°C
Purification Methods
Crystallise -ecdyson from water, tetrahydrofuran/pet ether, MeOH and EtOAc after chromatographic purification. It has max (EtOH) at 240nm ( 12,670 M-1cm-1). [Also IR & NMR: Hüppi & Siddall J Am Chem Soc 89 6799 1967, Kametani et al. Tetrahedron Lett 21 4855 1980, Beilstein 8 IV 343.]
Hydroxyecdysone Preparation Products And Raw materials
Global( 531)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| XI'AN TIANGUANGYUAN BIOTECH CO., LTD. | +86-029-86333380 18829239519 | sales06@tgybio.com | China | 961 | 58 |
| Xi'an ZB Biotech Co.,Ltd | +8618591943808 | sales01@xazbbio.com | China | 816 | 58 |
| Chengdu Greenpure Biopharma CO.,Ltd | 18283602253 | jancyzheng@gcgreenpure.com | China | 952 | 58 |
| Shaanxi LonierHerb Bio Technology Co Ltd | +86-86-+86-86-029-87551862 +8617702909819 | sales006@ingredients-lonier.com | China | 2596 | 58 |
| Wuhan Haorong Biotechnology Co.,ltd | +8618565342920 | sales@chembj.net | China | 269 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12457 | 58 |
| Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 | xie@china-sinoway.com | China | 992 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +86-13474506593 +86-13474506593 | sarah@tnjone.com | China | 864 | 58 |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 | admin@hbouhuang.com | China | 1175 | 58 |
Related articles
- Synthesis and Biological functions of 20-hydroxyecdysone
- 20-hydroxyecdysone (20E) is a steroid hormone conserved among arthropods. 20-hydroxyecdysone induces the transcription of many....
- Jun 20，2022
View Lastest Price from Hydroxyecdysone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-23 | Hydroxyecdysone
5289-74-7
|
US $15.00 / kg | 1kg | 99.912% | 10ton | Ouhuang Engineering Materials (Hubei) Co., Ltd | |
 |
2024-04-23 | Ecdysone / Ecdysterone
5289-74-7
|
US $180.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2024-04-23 | Hydroxyecdysone
5289-74-7
|
US $0.00-0.00 / kg | 1kg | 98% | 1000kg | Changsha Staherb Natural Ingredients Co., Ltd. |
-
- Hydroxyecdysone
5289-74-7
- US $15.00 / kg
- 99.912%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
-
- Ecdysone / Ecdysterone
5289-74-7
- US $180.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- Hydroxyecdysone
5289-74-7
- US $0.00-0.00 / kg
- 98%
- Changsha Staherb Natural Ingredients Co., Ltd.
5289-74-7(Hydroxyecdysone)Related Search:
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2B,3B,14A,20,22[R],25-HEXAHYDROXY-7-CHOLESTEN-6-ONE
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2BETA,3BETA,14ALPHA,20BETA,22,25-HEXAHYDROXY-7-CHOLESTEN-6-ONE
(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-TRIHYDROXY-10,13-DIMETHYL-17-((1R,2R)-1,2,5-TRIHYDROXY-1,5-DIMETHYL-HEXYL)-1,2,3,4,5,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-6-ONE
20-HYDROXYECDYSON
POLYPODINE A
2,3,14,20,22,25-hexahydroxy-,(2-beta,3-beta,5-beta,22r)-cholest-7-en-6-on
2-beta,3-beta,14,20,22,25-hexahydroxy-5-beta-cholet-7-en-6-one
3-beta,14,20,22,25-hexahydroxy-2-bet(22r)-5-beta-cholest-7-en-6-on
commisterone
crustecdyson
SS-ECDYSONE,2,3,14,20,22,25-HEXAHYDROXY-7-CHOLESTEN-6-ONE
20-HYDROXYECDYSONE (B-ECDYSTERONE)
β-Ecdysone, Ecdysterone, Insect moulting hormone, Polypodine A, 2β,3β,14α,20β,22,25-Hexahydroxy-7-cholesten-6-one
Beta Ecdysterone 95% UV, with 70% 20-hydroxyecdysterone
Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2b,3b,5b,22R)-
Polypodin A
Viticosterone
20-beta-ecdysterone
2β,3β,14α,20β,22,25-Hexahydroxy-7-cholesten-6-one
β-Ecdysone, Ecdysterone, Insect moulting hormone
ECDYSONE, BETA-(RG)(PLEASE CALL)
Edysterone
Ecdysten
20-Hydroxyecdysone,β-Ecdysone, 2β,3β,14α,20β,22,25-Hexahydroxy-7-cholesten-6-one, Ecdysterone, Insect moulting hormone, Polypodine A
ECDYSONE, B-(P)
20-Hydroxyedysone
(2β,3β,5β,22R)-2,3,14,20,22,25-Hexahydroxycholest-7-en-6-one
(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-diMethyl-17-((2R,3R)-2,3,6-trihydroxy-6-Methylheptan-2-yl)-2,3,4,5,9,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6(10H)-one
20-Hydroxyecdysone, froM Arachnoides C. B. Clarke
B-ecdysone,Commisterone
(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-((2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl)-1,2,3,4,5,10,11,12,13,15,16,17-dodecahydro-9H-cyclopenta[a]phenanthren-6(14H)-one
2β,3β,14α,20β,22,25-Hexahydroxycholest-7-en-6-one
20-Hydroxyecdysone, >=95%
hydroxyecdysone
HYDROXYECDYSONE, 20-
INSECT MOULTING HORMONE
ECDYSONE, BETA-
BETA-ECDYSON
isoinokosterone
the-7
BETA-ECDYSONE, 99% HPLC
BETA-ECDYSONE, 90% UV
BETA-ECDYSONE, 95+%
β-ECDYSONE,2,3,14,20,22,25-HEXAHYDROXY-7-CHOLESTEN-6-ONE
20-Hydroxyecdysone（β-Ecdysone ）
LEVETON
20-OH-ECDYSONE
BETAYSONE
20H-ECDYSONE
ECDYSONE, BETA-(P)
HYDROXYECDYSONE, 20-(SH)
BETA-ECDYSONE, 98+%
20-Hydroxyecdysone, 98%, from Arachnoides C. B. Clarke
Hydroxyecdysterone
professional manufacturer Ecdysterone 5289-74-7