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Guaifenesin

Description References

CAS No. 93-14-1
Chemical Name: Guaifenesin
Synonyms: 2-G;2/G;g87;gge;G 87;Dilyn;Gvaja;my301;Resil;Resyl
CBNumber: CB1743199
Molecular Formula: C10H14O4
Formula Weight: 198.22
MOL File: 93-14-1.mol
Guaifenesin Property
Melting point : 77-81 °C
Boiling point : 215 °C (19 mmHg)
Fp : 215°C/19mm
storage temp. : Refrigerator
solubility : 50g/l (experimental)
Water Solubility : 5 g/100 mL (25 ºC)
Merck : 14,4555
BRN : 2049375
CAS DataBase Reference: 93-14-1(CAS DataBase Reference)
NIST Chemistry Reference: 3-(O-methoxyphenoxy)-1,2-propanediol(93-14-1)
EPA Substance Registry System: 1,2-Propanediol, 3-(2-methoxyphenoxy)-(93-14-1)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes : Xn
Risk Statements : 22-36/37/38
Safety Statements : 26-36
WGK Germany : 1
RTECS : TY8400000
Hazard Note : Harmful
TSCA : Yes
Hazardous Substances Data: 93-14-1(Hazardous Substances Data)
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P321 Specific treatment (see … on this label).
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.
P501 Dispose of contents/container to..…

Guaifenesin Chemical Properties,Usage,Production

Description
Guaifenesin is an oral expectorant drug. The expectorant action of guaifenesin is mediated by stimulation of the gastrointestinal tract. It is a common ingredient in prescription and over-the-counter medications used to treat cough due to colds and minor upper respiratory infections.
References
[1] Peter V. Dicpinigaitis and Yvonne E. Gayle, Effect of Guaifenesin on Cough Reflex Sensitivity, 2003, vol. 124, 2178-2181
[2] Leonid Kagan, Eran Lavy and Ammon Hoffmann, Effect of mode of administration on guaifenesin pharmacokinetics and expectorant action in the rat model, Pulmonary Pharmacology & Therapeutics, 2009, vol. 22, 260-265
Chemical Properties
White Solid
Uses
Centrally acting muscle relaxant with expectorant properties
Uses
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guaifenesin Preparation Products And Raw materials
Raw materials
Ammonium hydroxide Guaiacol 3-Chloro-1,2-propanediol Diethyl carbonate
Preparation Products
Methocarbamol Zinc oxide Zinc nitrate hexahydrate Lithopone
Guaifenesin Suppliers      Global( 193)Suppliers     
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd. +86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19954 60
Shenzhen Sendi Biotechnology Co.Ltd. 0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3230 55
WUHAN YUANCHENG GONGCHUANG TECHNOLOGY CO.,LTD 021 6858 0971/18964558747
gclb4r@ycphar.com China 1995 55
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96832 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) sh@meryer.com China 40403 62
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 3bsc@sina.com China 15950 69
Alfa Aesar 400-610-6006; 021-67582000
021-67582001/03/05 saleschina@alfa-asia.com China 30315 84
TAIYUAN RHF CO.,LTD. +86 351 7031519
+86 351 7031519 sales@RHFChem.com China 2364 56
TCI (Shanghai) Development Co., Ltd. 800-988-0390
021-67121385 sales@tcishanghai.com.cn China 22833 81
Energy Chemical 021-58432009 / 400-005-6266
021-58436166-800 info@energy-chemical.com China 44198 61
 
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