oxeladin

CAS No.
468-61-1
Chemical Name:
oxeladin
Synonyms
oxeladin;oxeladin USP/EP/BP;IQADUMSPOQKAAO-UHFFFAOYSA-N;2-(β-1Diethylaminoethoxy)ethyl diethylphenyl acetate;2-(2-diethylaminoethoxy)ethyl 2-ethyl-2-phenylbutyrate;2-[2-(Diethylamino)ethoxy]ethyl 2-ethyl-2-phenylbutanoate;α,α-Diethylbenzeneacetic acid 2-(2-diethylaminoethoxy)ethyl ester;2-Ethyl-2-phenylbutyric acid 2-[2-(diethylamino)ethoxy]ethyl ester;Benzeneacetic acid, α,α-diethyl-, 2-[2-(diethylamino)ethoxy]ethyl ester
CBNumber:
CB1875328
Molecular Formula:
C20H33NO3
Molecular Weight:
335.48
MDL Number:
MFCD00242637
MOL File:
468-61-1.mol
Last updated:2023-05-04 17:34:39

oxeladin Properties

Melting point 25°C
Boiling point bp0.5 150°; bp0.1 140°
Density 1.0720 (rough estimate)
refractive index 1.5614 (estimate)
FDA UNII SNC1080T5Y
ATC code R05DB09

SAFETY

Risk and Safety Statements

oxeladin price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0016280 OXELADIN 95.00% 468-61-1 5MG $498.48 2021-12-16 Buy
Product number Packaging Price Buy
API0016280 5MG $498.48 Buy

oxeladin Chemical Properties,Uses,Production

Originator

Silopentol,Schulte,W. Germany ,1970

Uses

Oxeladin can be used in ex vivo modeling of drug efficacy in rare metastatic urachal carcinoma.

Definition

ChEBI: Oxeladin is an alkylbenzene.

Manufacturing Process

Preparation of Diethylphenylacetonitrile: 25 grams of sodium was dissolved in 300 ml liquid ammonia containing 0.3 gram ferric chloride and 59 grams phenylacetonitrile was added slowly with stirring. After about 15 minutes a cooled solution of 80 grams of ethyl chloride in 200 ml dry ether was added and the mixture stirred for 1 hour. The ammonia was then allowed to evaporate, water added and the ether layer separated, dried, concentrated and the residual oil distilled in vacuo to yield diethylphenylacetonitrile as an oil, BP 85°C/1 mm.
Preparation of Diethylphenylacetic Acid: 46 grams of the foregoing nitrile was added to 140 ml ethylene glycol containing 36 grams potassium hydroxide and the mixture refluxed with stirring for about 20 hours. The mixture was diluted with water, extracted with light petroleum (BP 60° to 80°C) to remove traces of impurities and then acidified to yield diethylphenylacetic acid which was recrystallized from dilute ethanol (40% v/v ethanol in water).
Preparation of 2-(β-Chloroethoxy)Ethyl Diethylphenylacetate: 19.2 grams of the foregoing acid was added to a solution of 4 grams of sodium hydroxide in 40 ml ethylene glycol. 28.6 grams β,β'-dichlorodiethyl ether was added and the mixture refluxed for 1 hour. After removal of solvent under reduced pressure, 150 ml water was added to the residue and the product extracted with ether. The ethereal solution was dried, concentrated and the residue distilled in vacuo to yield the product as an oil, BP 140°C/0.7 mm.
Preparation of 2-(β-Diethylaminoethoxy)Ethyl Diethylphenylacetate: A mixture of 21 grams of 2-(β-chloroethoxy)ethyl diethylphenylacetate and 14 grams diethylamine was heated under pressure in a sealed tube at 140°C for 5 hours. After cooling, the mixture was dissolved in dilute hydrochloric acid and extracted with ether to remove traces of neutral impurities. The acid layer was then made alkaline with 10% w/v sodium hydroxide solution with cooling, and re-extracted with two portions of ether. The ether extract was dried, the ether distilled off and the residue distilled in vacuo to yield the product as an oil, BP 140°C/0.1 mm.

Therapeutic Function

Antitussive

oxeladin Preparation Products And Raw materials

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Shaanxi Dideu Medichem Co. Ltd
18192627656 1012@dideu.com China 3911 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 29831 58
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Wuhan pengyin Pharmaceutical Co., Ltd 13163333255 1939328613@qq.com China 395 58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 029-81148696 18161915376 1040@dideu.com China 10011 58

View Lastest Price from oxeladin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
oxeladin USP/EP/BP pictures 2021-06-01 oxeladin USP/EP/BP
468-61-1
US $1.10 / g 1g 99.9% 100Tons min Dideu Industries Group Limited
Oxeladin   pictures 2020-04-25 Oxeladin
468-61-1
US $0.01-1.00 / KG 1KG 99% 50 tons Shaanxi Dideu Medichem Co. Ltd
  • Oxeladin   pictures
  • Oxeladin
    468-61-1
  • US $0.01-1.00 / KG
  • 99%
  • Shaanxi Dideu Medichem Co. Ltd

468-61-1(oxeladin)Related Search:

2-(2-diethylaminoethoxy)ethyl 2-ethyl-2-phenylbutyrate oxeladin 2-(β-1Diethylaminoethoxy)ethyl diethylphenyl acetate 2-Ethyl-2-phenylbutyric acid 2-[2-(diethylamino)ethoxy]ethyl ester α,α-Diethylbenzeneacetic acid 2-(2-diethylaminoethoxy)ethyl ester IQADUMSPOQKAAO-UHFFFAOYSA-N 2-[2-(Diethylamino)ethoxy]ethyl 2-ethyl-2-phenylbutanoate Benzeneacetic acid, α,α-diethyl-, 2-[2-(diethylamino)ethoxy]ethyl ester oxeladin USP/EP/BP 468-61-1 468-68-1