ChemicalBook >> CAS DataBase List >>Benzamide, 4-[3-[(3aR,6aS)-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]propoxy]-, rel-

Benzamide, 4-[3-[(3aR,6aS)-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]propoxy]-, rel-

Benzamide, 4-[3-[(3aR,6aS)-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]propoxy]-, rel- structure

CAS No.: 1403835-45-9

Chemical Name:: Benzamide, 4-[3-[(3aR,6aS)-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]propoxy]-, rel-

Synonyms: Benzamide, 4-[3-[(3aR,6aS)-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]propoxy]-, rel-

CBNumber:: CB19935582

Molecular Formula:: C17H24N2O2

Molecular Weight:: 288.38

MDL Number:

MOL File:: 1403835-45-9.mol

Last updated:2023-06-30 15:45:59

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Benzamide, 4-[3-[(3aR,6aS)-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]propoxy]-, rel- Properties

Boiling point	473.5±25.0 °C(Predicted)
Density	1.130±0.06 g/cm3(Predicted)
solubility	Soluble to 100 mM in DMSO and to 50 mM in ethanol
pka	16.34±0.50(Predicted)

Benzamide, 4-[3-[(3aR,6aS)-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]propoxy]-, rel- Chemical Properties,Uses,Production

Biological Activity

S 38093 is a H3 antagonist and inverse agonist (Ki values are 8.8, 1.2 and 1.44 μM, at rat, human and mouse, respectively). Exhibits no activity at other histaminergic receptors. Antagonizes agonist action at mouse H3 receptors (KB = 0.65 μM). Displays inverse agonist action in cells expressing a high H3 receptor density, (EC50 values are 9 and 1.7 μM, at human and rat H3 receptors, respectively). Exhibits antihyperalgesic effect in a mouse diabetic neuropathy model in vivo. Promotes hippocampal neurogenesis in a mouse Alzheimer's disease model. Antinociceptive and procognitive. Also σ1 receptor antagonist. Exhibits ~30-fold selecitivity for σ1 over H3 and occupies σ1 but not H3 receptors at procognitive does in mice.

storage

Store at -20°C

Benzamide, 4-[3-[(3aR,6aS)-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]propoxy]-, rel- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzamide, 4-[3-[(3aR,6aS)-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]propoxy]-, rel- Suppliers

Global( 3)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Shanghai Dexuan Pharmaceutical Technology Co., Ltd	1701086315	dexuanpharma@126.com	China	9478	58
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	4164	58

Supplier	Advantage
Aladdin Scientific	58
Shanghai Dexuan Pharmaceutical Technology Co., Ltd	58
Nantong QuanYi Biotechnology Co., Ltd	58

Benzamide, 4-[3-[(3aR,6aS)-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]propoxy]-, rel- 1403835-45-9