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Vanillylidenacetone

CAS No.
1080-12-2
Chemical Name:
Vanillylidenacetone
Synonyms
mhsk;FEMA 3738;feruloylmethane;vanillalacetone;DEHYDROZINGERONE;Dehydrogingerone;dehydro(o)-paradol;Vanillideneacetone;VANILLYLIDENACETONE;VANILLYLIDENEACETONE
CBNumber:
CB2126546
Molecular Formula:
C11H12O3
Molecular Weight:
192.21
MDL Number:
MFCD00012210
MOL File:
1080-12-2.mol
MSDS File:
SDS
Last updated:2023-05-25 18:01:01

Vanillylidenacetone Properties

Melting point 125-130 °C
Boiling point 268.19°C (rough estimate)
Density 1.1503 (rough estimate)
refractive index 1.4600 (estimate)
FEMA 3738 | VANILLYLIDENE ACETONE
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
form solid
pka 9.94±0.31(Predicted)
color Pale yellow
Odor at 100.00 %. sweet powdery vanilla creamy balsam
Odor Type vanilla
JECFA Number 732
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
LogP 1.40
CAS DataBase Reference 1080-12-2(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) VANILLYLIDENE ACETONE
EWG's Food Scores 1
FDA UNII 8CJX5I27B7
EPA Substance Registry System 3-Buten-2-one, 4-(4-hydroxy-3-methoxyphenyl)- (1080-12-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Risk Statements  36/37/38
Safety Statements  26-36/37/39
WGK Germany  3
RTECS  EM9960000
10-23
HS Code  29145090
Toxicity LD50 intraperitoneal in mouse: 610mg/kg

Vanillylidenacetone price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 07551 Vanillylidenacetone ≥98.5% 1080-12-2 5G-F $102 2023-06-20 Buy
Sigma-Aldrich 07551 Vanillylidenacetone ≥98.5% 1080-12-2 5G $102 2023-01-07 Buy
Sigma-Aldrich 90609 Vanillylidenacetone analytical standard 1080-12-2 100mg $69.5 2022-05-15 Buy
TRC H533360 4-(4-Hydroxy-3-methoxyphenyl)-3-buten-2-one 1080-12-2 10g $60 2021-12-16 Buy
TRC H533360 4-(4-Hydroxy-3-methoxyphenyl)-3-buten-2-one 1080-12-2 5g $45 2021-12-16 Buy
Product number Packaging Price Buy
07551 5G-F $102 Buy
07551 5G $102 Buy
90609 100mg $69.5 Buy
H533360 10g $60 Buy
H533360 5g $45 Buy

Vanillylidenacetone Chemical Properties,Uses,Production

Description

Dehydrozingerone (1080-12-2) is a structural half analog of curcumin (Cat.# 10-1243) and is isolated from ginger rhizomes. Dehydrozingerone displays antioxidant, antibacterial and antifungal properties.1 It has also been shown to possess various antitumor effects2,3 and inhibit growth factor/peroxide-stimulated vascular smooth muscle function4.

Chemical Properties

Vanillylidene acetone has a very sweet, warm and tenacious odor.

Uses

Vanillylidenacetone is one of ferulic acid derivatives. Studies have shown that vanillyl acetone has a certain inhibitory effect on Amaranthus, barnyardgrass, matang, dogwood and rape, among which the best inhibitory effect is on rape and Amaranthus.

Definition

ChEBI: Dehydrozingerone is a hydroxycinnamic acid.

Taste threshold values

Taste characteristics at 200 ppm: balsamic vanilla, with sweet aromatic spicy nuances.

References

1) Kubra et al. (2014), Structure-function activity of dehydrozingerone and its derivatives as antioxidant and antimicrobial compounds; J. Food Sci. Technol., 51 245 2) Motohashi et al. (1998), Inhibitory effects of dehydrozingerone and related compounds on 12-O-tetradecanoylphorbol-13-acetate induced Epstein-Barr virus early antigen activation; Cancer Lett., 134 37 3) Yogosawa et al. (2012), Dehydrozingerone, a structural analog of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells; J. Nat. Prod., 75 2088 4) Liu et al. (2008), Inhibitory effect of dehydrozingerone on vascular smooth muscle cell function; J. Cardiovasc. Pharmacol., 52 422

Vanillylidenacetone Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 96)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21149 58
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
WinWin Chemical CO., Limited
+86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 13854 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167 1026@dideu.com China 9409 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 29322 58
Henan Alfa Chemical Co., Ltd
+8618339805032 alfa4@alfachem.cn China 12755 58
sgtlifesciences pvt ltd
+8617013299288 dj@sgtlifesciences.com China 12382 58

View Lastest Price from Vanillylidenacetone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Vanillylidene acetone  pictures 2020-02-26 Vanillylidene acetone
1080-12-2
US $0.00-0.00 / KG 100g 99.0%+ 100 tons Shaanxi Dideu Medichem Co. Ltd
VANILLYLIDENACETONE VANILLYLIDENEACETONE VANILLYLIDINE ACETONE FEMA 3738 DEHYDROZINGERONE 4-(4-hydroxy-3-methoxyphenyl)-3-buten-2-on dehydro(o)-paradol feruloylmethane 4-(4-HYDROXY-3-METHOXYPHENYL)-3-BUTEN-2-ONE 4-(4-HYDROXY-3-METHOXYPHENYL)-3-BUTENE-2-ONE 4-(4-HYDROXY-3-METHOXYPHENYL)BUT-3-EN-2-ONE methyl-3-methoxy-4-hydroxystyrylketone mhsk vanillalacetone Vanillideneacetone 3-Buten-2-one, 4-(4-hydroxy-3-methoxyphenyl)- 4-(3-Methoxy-4-hydroxyphenyl)-3-butene-2-one Dehydrogingerone Ferulic methyl ketone Vanillylideneacetone ,98% Dehydrozingerone Vanillylideneacetone 4-(4- hydroxy-3-Methoxyphenyl)-3- butene-2- ketone 4-(4-Hydroxy-3-methoxyphenyl)-3-buten-2-one,predominantly trans Vanillylidenacetone >=98.5% 4-(4-Hydroxy-3-methoxyphenyl)-3-buten-2-one> 4-(4-HYDROXY-3-METHOXYPHENYL)-3-BUTEN-2-ONE USP/EP/BP Vanilllylideneacetone 98%(Pre-trans) 4-(-HYDROXY-3-METHOXYPHENYL)-3-BUTEN-2-ONE 1080-12-2 1080-12-02 CH3COCHCHC6H3OCH3OH C11 to C12 Carbonyl Compounds Building Blocks Ketones Organic Building Blocks Aromatic Ketones (substituted)