ChemicalBook >> CAS DataBase List >>FMOC-S-trityl-L-cysteine

FMOC-S-trityl-L-cysteine

CAS No.
103213-32-7
Chemical Name:
FMOC-S-trityl-L-cysteine
Synonyms
FMOC-CYS(TRT)-OH;FMOC-CYS(TRT);FMOC-L-CYS(TRT)-OH;Fomc-Cys(Trt)-OH;N-FMOC-S-TRITYL-L-CYSTEINE;Fmoc-Cyc(Trt)-OH;FMOC-L-CYS(TRT);Fmoc-Cys(Trt)-0H;FMOC-L-CYS(TRITYL);N-FMOC-L-CYS(TRT)-OH
CBNumber:
CB2138770
Molecular Formula:
C37H31NO4S
Molecular Weight:
585.71
MDL Number:
MFCD00038538
MOL File:
103213-32-7.mol
MSDS File:
SDS
Last updated:2024-03-22 11:53:02

FMOC-S-trityl-L-cysteine Properties

Melting point 170-173 °C(lit.)
Boiling point 763.4±60.0 °C(Predicted)
alpha 16 º (c=1, THF)
Density 1.270±0.06 g/cm3(Predicted)
refractive index 18 ° (C=1, THF)
storage temp. 2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka 3.70±0.10(Predicted)
form Powder
color White to almost white
optical activity [α]20/D +16.0±2°, c = 1% in THF
Water Solubility Insoluble in water. Soluble in most organic solvents.
BRN 4221286
InChIKey KLBPUVPNPAJWHZ-UMSFTDKQSA-N
CAS DataBase Reference 103213-32-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-26
WGK Germany  3
9-21
Hazard Note  Irritant
HS Code  29309090
NFPA 704
1
0 0

FMOC-S-trityl-L-cysteine price More Price(64)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.52008 Fmoc-Cys(Trt)-OH Novabiochem? 103213-32-7 25g $72.8 2024-03-01 Buy
Sigma-Aldrich 8.52008 Fmoc-Cys(Trt)-OH Novabiochem? 103213-32-7 100g $183 2024-03-01 Buy
Sigma-Aldrich 8.52008 Fmoc-Cys(Trt)-OH Novabiochem? 103213-32-7 250g $365 2024-03-01 Buy
Sigma-Aldrich 8.52008 Fmoc-Cys(Trt)-OH Novabiochem? 103213-32-7 1kg $1370 2024-03-01 Buy
Sigma-Aldrich 47695 Fmoc-Cys(Trt)-OH ≥95.0% (sum of enantiomers, HPLC) 103213-32-7 100g $75.2 2024-03-01 Buy
Product number Packaging Price Buy
8.52008 25g $72.8 Buy
8.52008 100g $183 Buy
8.52008 250g $365 Buy
8.52008 1kg $1370 Buy
47695 100g $75.2 Buy

FMOC-S-trityl-L-cysteine Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powde

Uses

Fmoc-Cys(Trt)-OH is an N-terminal protected cysteine derivative used in peptide synthesis. Some of the examples are:

  • Synthesis of mono- and bi-functionalized platinum(IV) complexes to target angiogenic tumor vasculature.
  • Synthesis of proteins through native chemical ligation of peptide hydrazides as thioester surrogates via solid-phase synthesis.
  • Synthesis of glycoconjugates by conjugating reducing sugars to cysteine residues of peptides.

Uses

It is potentially useful for proteomics studies, and solid phase peptide synthesis techniques. Cysteine is versatile amino acid involved with many biological processes, including the formation of disulfide bonds - a critical component of protein structure. This compound could be useful as an unusual amino acid analog to aid in the deconvolution of protein structure and function.

General Description

The standard derivative for Fmoc SPPS of peptides containing Cys [1]. The Trt group is removed with 95% TFA containing 1-5% TIS. Ideally, this derivative should be introduced using the symmetrical anhydride or DIPCDI/HOBt activation [2,3] to minimize enantiomerization. If activation with uronium or phosphonium reagents, such as HBTU or PyBOP?, is to be employed, it is strongly recommended that collidine is used as the base [4], as this has been shown to significantly reduce loss of optical integrity during coupling.

The product number for this product was previously 04-12-1018.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

FMOC-S-trityl-L-cysteine Preparation Products And Raw materials

Global( 475)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu Baishixing Science and Technology Industry Co.,Ltd
+86-15008457246 +86-15008457246 yuki@cd-bsx.com China 53 58
Sichuan HongRi Pharma-Tech Co.,Ltd
+86-028-64841719 +8618980456393 daisy@enlaibio.com China 1369 58
hebei hongtan Biotechnology Co., Ltd
+86-86-1913198-3935 +8617331935328 sales03@chemcn.cn China 951 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15928 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10248 58
Jinan Finer Chemical Co., Ltd
+86-531-88989536 +86-15508631887 sales@finerchem.com China 2967 58

View Lastest Price from FMOC-S-trityl-L-cysteine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fmoc-L-Cys(trt)-OH pictures 2024-04-24 Fmoc-L-Cys(trt)-OH
103213-32-7
US $0.00-0.00 / kg 1kg 98% 1T Sichuan HongRi Pharma-Tech Co.,Ltd
FMOC-S-trityl-L-cysteine pictures 2024-04-24 FMOC-S-trityl-L-cysteine
103213-32-7
US $0.00 / kg 1kg 99% 200mt/year Jinan Finer Chemical Co., Ltd
FMOC-S-trityl-L-cysteine pictures 2024-04-22 FMOC-S-trityl-L-cysteine
103213-32-7
US $30.00 / kg 1kg 98% 2000kg hebei hongtan Biotechnology Co., Ltd

FMOC-S-trityl-L-cysteine Spectrum

FMOC-CYSTEINE(TRT)-OH FMOC-L-CYSTEINE(TRITYL) FMOC-L-CYSTEINE (TRT) FMOC-L-CYS(TRITYL) FMOC-L-CYS(TRT) FMOC-S-TRITYL-L-CYSTEINE 2-[[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]AMINO]-3-(TRITYLTHIO)PROPANOIC ACID L-CYSTEINE-N-FMOC, S-TRITYL 9-FLUORENYLMETHOXYCARBONYL-S-TRITYL-L-CYSTEINE S-TRITYL-L-CYSTEINE, N-FMOC PROTECTED N-ALPHA-FMOC-S-TRITYL-L-CYSTEINE N-(9-FLUORENYL METHOXY CARBONYL)-S-TRITYL-L-CYSTEINE N-9-FLUORENYLMETHYLOXYCARBONYL-S-TRITYL-L-CYSTEINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-S-TRITYL-L-CYSTEINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-S-TRITYL-L-CYSTEINE N-FMOC-L-CYS(TRT)-OH (R)-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-3-TRITYLSULFANYL-PROPIONIC ACID FMoc-Cys(Trt)-OH FMoc-S-trityl-L-cysteine N-Fmoc-S-trityl-L-cysteine Fmoc-Cys(Trt)-OH (R)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-3-(tritylthio)propanoic acid (R)-(9H-Fluoren-9-yl)methyl (1-hydroxy-3-(tritylthio)propan-2-yl)carbamate Fmoc-Cys(Trt)-OH >=95.0% (sum of enantiomers, HPLC) Fmoc-Cys(Trt)-OH, >=99% (R)-2-Fmoc-3-tritylsulfanyl-propionic acid Fmoc-S-trityl-L-cysteine≥ 99.7% (HPLC, Chiral purity) n-(alpha)-fluorenylmethyloxycarbonyl-s-tritylcysteine N-(9-FLUORENYLMETHOXYCARBONYL)-S- FMOC-CYS(TRT)-OH, 98+% N-(9-Fluorenylmethoxycarbonyl)-S-trityl-L-cystei L-Cysteine-3,3-D2-N-FMOC-S-Trityl L-Cysteine-N-FMOC-UL-13C3, 15N, S-Trityl N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-S-(TRIPHENYLMETHYL)-L-CYSTEINE FMOC-S-TRITYL-L-CYSTEINE (FMOC-L-CYS(TRT)-OH) (R)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)cysteine (9-fluorenylmethoxycarbonyl)-L-cysteine (trityl) N-(9-Fluorenylmethoxycarbonyl)-S-trityl-L-cysteine, Nα-Fmoc-S-trityl-L-cysteine Nα-(9-Fluorenylmethoxycarbonyl)-S-trityl-L-cysteine ,98% N-[(9H-Fluoren-9-yloxy)carbonyl]-S-trityl-L-cysteine FMOC-S-trityl-L-Cysteine,97% Nα-Fmoc-S-trityl-L-c (9H-Fluoren-9-yl)MethOxy]Carbonyl Cys(Trt)-OH (Cys of Non-Animal Origin) (9H-Fluoren-9-yl)MethOxy]Carbonyl Cys(Trt)-OH (Cys of Animal Origin) Fmoc-Cys(Trt)-OH(Animal origin) Fmoc-Cys(Trt)-OH(Non-Animal origin) (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-[(triphenylmethyl)sulfanyl]propanoic acid (2S)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-[(triphenylmethyl)thio]propanoate S-Trityl-N-Fomc_L-Cysteine N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-L-cysteine> FMOC-CYS(TRT)-OH 25 G FMOC-CYS(TRT)-OH 100 G FMOC-CYS(TRT)-OH 250 G L-Cysteine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)- Fmoc-Cys(Trt)-OH(animal) Fmoc-Cys(Trt)-OH Fmoc-Cys(Trt)-OH FMOC-S-trityl-L-cysteine USP/EP/BP (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-tritylsulfanylpropanoic acid FMOC-S-trChemicalbookityl-L-cysteine FMOC-CYS(TRT)