5-Chloro-1-indanone
- CAS No.
- 42348-86-7
- Chemical Name:
- 5-Chloro-1-indanone
- Synonyms
- 5-Chloro-2,3-dihydro-1H-inden-1-one;Chloro-1-indan;5-Chloro Indanone;5- chlorineindone;5-CHLORO-1-INDANONE;5-CHLOROINDAN-1-ONE;1-Indanone, 5-chloro-;5-Chloro-1-indanone,99%;5-Chloro-1-indanone,98%;5-Chloro-1-indanone >
- CBNumber:
- CB2148511
- Molecular Formula:
- C9H7ClO
- Molecular Weight:
- 166.6
- MDL Number:
- MFCD00041456
- MOL File:
- 42348-86-7.mol
| Melting point | 94-98 °C (lit.) |
|---|---|
| Boiling point | 124-125 °C (3 mmHg) |
| Density | 1.1466 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| Flash point | 124-125°C/3mm |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly) |
| form | Solid |
| color | Light Beige to Beige |
| Water Solubility | insoluble |
| BRN | 1448000 |
| InChIKey | MEDSHTHCZIOVPU-UHFFFAOYSA-N |
| CAS DataBase Reference | 42348-86-7(CAS DataBase Reference) |
| NIST Chemistry Reference | 5-Chloro-1-indanone(42348-86-7) |
| EPA Substance Registry System | 1H-Inden-1-one, 5-chloro-2,3-dihydro- (42348-86-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
5-Chloro-1-indanone price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 433071 | 5-Chloro-1-indanone 99% | 42348-86-7 | 5g | $62.3 | 2024-03-01 | Buy |
| TCI Chemical | C1644 | 5-Chloro-1-indanone >97.0%(GC) | 42348-86-7 | 1g | $65 | 2024-03-01 | Buy |
| TCI Chemical | C1644 | 5-Chloro-1-indanone >97.0%(GC) | 42348-86-7 | 5g | $212 | 2024-03-01 | Buy |
| Alfa Aesar | A18308 | 5-Chloro-1-indanone, 99% | 42348-86-7 | 1g | $46.65 | 2024-03-01 | Buy |
| Alfa Aesar | A18308 | 5-Chloro-1-indanone, 99% | 42348-86-7 | 5g | $180.65 | 2024-03-01 | Buy |
5-Chloro-1-indanone Chemical Properties,Uses,Production
Chemical Properties
White Crystal
Uses
5-Chloro-1-indanone may be used as starting reagent for the preparation of 5-chloro-2-methoxycarbonyl-1-indanone. It may also be used for the preparation of important biomedical compounds such as anticonvulsants, anticholinergics and diarylsulfonylureas, having potential activity against solid tumors. It participates in the Irie?s synthesis of substituted pyridines.
Uses
5-Chloro-1-indanone is the important intermediate of du pont company's new varieties of pesticides indoxacarb (popular name: indoxacarb), is also a kind of important medicine intermediate simultaneously.
5-Chloro-1-indanone is a 5-halo-1-indanone. It participates in the Irie′s synthesis of substituted pyridines. 5-Chloro-1-indanone has a stable triclinic crystal structure and has intermolecular forces of C-H...O, C-H...Π, CO...Cl and Π...Π types.
5-Chloro-1-indanone may be used as starting reagent for the preparation of 5-chloro-2-methoxycarbonyl-1-indanone. It may be used for the preparation of important biomedical compounds such as anticonvulsants, anticholinergics and diarylsulfonylureas, having potential activity against solid tumors.
Preparation
3-chlorobenzaldehyde as raw material first reacts with propionic acid to prepare 3-chloro-phenylpropionic acid, which is then subjected to Friedel-Crafts acylation reaction to prepare 5-chloro-1-indanone. Organic solvents of formic acid diethylamine participate in the first step, and the reaction temperature is 20-150℃. An organic solvent of methylene chloride and a catalyst of zinc chloride participate in the second step, and the reaction temperature is -10 to 80 ℃.
Synthetic method of 5-chloro-1-indanone
General Description
5-Chloro-1-indanone is a 5-halo-1-indanone. It participates in the Irie′s synthesis of substituted pyridines. 5-Chloro-1-indanone has a stable triclinic crystal structure and has intermolecular forces of C-H...O, C-H...Π, CO...Cl and Π...Π types.
5-Chloro-1-indanone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Zhengzhou Anbu Chem Co.,Ltd | +86-0371-88006763; +8615988602810 | sales@anbuchem.com | China | 3000 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
| Zibo Wei Bin Import & Export Trade Co. Ltd. | +86-0533-2091136 +8613864437655 | ziboweibinmaoyi@163.com | China | 100 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 8095 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15933 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
View Lastest Price from 5-Chloro-1-indanone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-07 | 5-Chloro-1-indanone
42348-86-7
|
US $0.00 / kg | 1kg | 98% | 100 | Zibo Wei Bin Import & Export Trade Co. Ltd. | |
 |
2024-01-22 | 5-Chloro-1-indanone
42348-86-7
|
US $8.00-0.80 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2024-01-08 | 5-Chloro-1-Indanone
42348-86-7
|
US $50.00-30.00 / kg | 1kg | 99.50% | 20tons | Wuhan Boyuan Import & Export Co., LTD |
-
- 5-Chloro-1-indanone
42348-86-7
- US $0.00 / kg
- 98%
- Zibo Wei Bin Import & Export Trade Co. Ltd.
-
- 5-Chloro-1-indanone
42348-86-7
- US $8.00-0.80 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 5-Chloro-1-Indanone
42348-86-7
- US $50.00-30.00 / kg
- 99.50%
- Wuhan Boyuan Import & Export Co., LTD