Benzimidazole
- CAS No.
- 51-17-2
- Chemical Name:
- Benzimidazole
- Synonyms
- 1H-BENZO[D]IMIDAZOLE;1H-BENZIMIDAZOLE;Benzimidazol;BZI;Benzoimidazole;3-Azaindole;Benziminazole;1H-Benzoimidazole;nsc759;Azindol
- CBNumber:
- CB2177003
- Molecular Formula:
- C7H6N2
- Molecular Weight:
- 118.14
- MDL Number:
- MFCD00005585
- MOL File:
- 51-17-2.mol
- MSDS File:
- SDS
| Melting point | 169-171 °C (lit.) |
|---|---|
| Boiling point | 360 °C |
| Density | 1.1151 (rough estimate) |
| refractive index | 1.5500 (estimate) |
| Flash point | 360°C |
| storage temp. | Store below +30°C. |
| solubility | xylene: soluble1g in 2g (boiling)(lit.) |
| form | Crystalline Powder or Crystals |
| pka | 5.532(at 25℃) |
| color | Beige to brown |
| Water Solubility | sparingly soluble |
| λmax | 271nm(MeOH)(lit.) |
| Merck | 14,1081 |
| BRN | 109682 |
| Stability | Stable. Combustible. Incompatible with strong oxidising agents. |
| InChIKey | HYZJCKYKOHLVJF-UHFFFAOYSA-N |
| LogP | 1.320 |
| CAS DataBase Reference | 51-17-2(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | E24GX49LD8 |
| NIST Chemistry Reference | 1H-Benzimidazole(51-17-2) |
| EPA Substance Registry System | Benzimidazole (51-17-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P501 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 37/39-26-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DD5425000 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29339990 | |||||||||
| Toxicity | LD50 oral in mouse: 2910mg/kg | |||||||||
| NFPA 704 |
|
Benzimidazole price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.21956 | Benzimidazole for synthesis | 51-17-2 | 100g | $64.6 | 2024-03-01 | Buy |
| Sigma-Aldrich | 194123 | Benzimidazole 98% | 51-17-2 | 5g | $76 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.21956 | Benzimidazole for synthesis | 51-17-2 | 500g | $249 | 2024-03-01 | Buy |
| Sigma-Aldrich | 194123 | Benzimidazole 98% | 51-17-2 | 100g | $90.9 | 2024-03-01 | Buy |
| TCI Chemical | B0054 | Benzimidazole >98.0%(GC)(T) | 51-17-2 | 25g | $19 | 2024-03-01 | Buy |
Benzimidazole Chemical Properties,Uses,Production
Chemical Properties
white crystals
Uses
Usually used as template compound in the preparation of molecularly imprinted polymer via electropolymerization and electrodeposition of pyrrole on a pencil graphite electrode,and also used in the preparation of benzimidazolium surfactant, 1-hexadecyl-1H-benzimidazole.
Uses
Benzimidazole is a building block for making anthelmintic drugs like albendazole, mebendazole and triclabendazole and anti-ulcer drugs like pantoprazole, rabeprazole, lansoprazole and omeprazole. It is used in the preparation of pyrene derived benzimidazole linked polymers (BILPs), which are used for selective carbon dioxide separation applications due to their properties like porous materials, regenerability and sorbent selection parameters.
Definition
ChEBI: 1H-benzimidazole is the 1H-tautomer of benzimidazole. It is a benzimidazole and a polycyclic heteroarene. It is a conjugate acid of a benzimidazolide. It is a tautomer of a 4H-benzimidazole, a 2H-benzimidazole and a 3aH-benzimidazole.
General Description
White tabular crystals.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
An amine. Neutralizes acids to form salts plus water. These acid-base reactions are exothermic. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides. May be shock sensitive.
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition Benzimidazole emits highly toxic fumes.
Fire Hazard
Flash point data for Benzimidazole are not available. Benzimidazole is probably combustible.
Pharmacology
The mode of action of benzimidazoles has been described in several comprehensive reviews (1,32,33). The primary mode of action of benzimidazoles has been identified as the specific binding to the β-subunit of fungal tubulin and, consequently, an interference with microtubule assembly. Microtubules are major components of the fungal cytoskeleton and are involved in meiosis and mitosis, both of which are blocked in the presence of benzimidazoles.
Safety Profile
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits highly toxic fumes of NOx.
Purification Methods
It crystallises from water or aqueous EtOH (charcoal) and is dried at 100o for 12hours. [Beilstein 23 H 131, 23/6 V 196.]
Benzimidazole Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Junwee Chemical co., Ltd. | +86-571-85808636 +86-13958122542 | sales@junweechem.com | China | 821 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12453 | 58 |
| Firsky International Trade (Wuhan) Co., Ltd | +8615387054039 | admin@firsky-cn.com | China | 436 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7377 | 58 |
| Hebei Saisier Technology Co., LTD | +86-18400010335 +86-13102810335 | admin@hbsaisier.cn | China | 424 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1807 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| Nanjing MSN chemical Co., Ltd | 25-57015632 +8618913029712 | export@msnchem.com | China | 25 | 34 |
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- Feb 11，2022
View Lastest Price from Benzimidazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-12 | Benzimidazole
51-17-2
|
US $6.00 / KG | 25KG | MORE THAN 99% | 20000KG/MONTH | Hebei Saisier Technology Co., LTD | |
 |
2024-03-31 | Benzimidazole
51-17-2
|
US $30.00-10.00 / BOX | 10BOX | 99 | 20TONS | Shanghai Chinqesen Biotechnology Co., Ltd. | |
 |
2024-03-16 | Benzimidazole
51-17-2
|
US $0.00 / KG | 100g | 98%+ | 100kg | WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD |
-
- Benzimidazole
51-17-2
- US $6.00 / KG
- MORE THAN 99%
- Hebei Saisier Technology Co., LTD
-
- Benzimidazole
51-17-2
- US $30.00-10.00 / BOX
- 99
- Shanghai Chinqesen Biotechnology Co., Ltd.
-
- Benzimidazole
51-17-2
- US $0.00 / KG
- 98%+
- WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD