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ChemicalBook >> CAS DataBase List >>1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent Structure
1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent structure
CAS No.
887144-97-0
Chemical Name:
1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent
Synonyms
Togni Reagent;3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole;Togni's Reagent;1-Trifluoromethyl-3,3-dimethyl-1,2-benziodoxole;togni's reagent;3,3-DMethyl-1-(trifluoroMethyl)-1,2-benziodoxole;3,3-Dimethyl-1-(trifluoromethyl)-1,2-benzodioxole;1,3-Dihydro-3,3-diMethyl-1-(trifluoroMethyl)-1,2-b;1,2-Benziodoxole,3,3-dimethyl-1-(trifluoromethyl)-;3,3-dimethyl-1-(trifluoromethyl)-1λ3,2-benziodoxole
CBNumber:
CB22101080
Molecular Formula:
C10H10F3IO
Molecular Weight:
330.09
MDL Number:
MFCD10567056
MOL File:
887144-97-0.mol
MSDS File:
SDS
Last updated:2023-06-08 17:06:36
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1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent Properties

Melting point 75-79 °C
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
form powder
color white to off-white
Stability Moisture Sensitive
InChIKey HVAPLSNCVYXFDQ-UHFFFAOYSA-N
FDA UNII 3OK0E02MT6

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Warning
Hazard statements  H228-H315-H319-H335
Precautionary statements  P210-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37
RIDADR  1325
WGK Germany  3
TSCA  No
HazardClass  4.1
PackingGroup  Ⅲ
HS Code  29349990
NFPA 704
0
2 0

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 696641 3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole 95% 887144-97-0 5g $342 2024-03-01 Buy
Sigma-Aldrich 696641 3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole 95% 887144-97-0 1g $442 2024-03-01 Buy
TCI Chemical T2624 1-Trifluoromethyl-3,3-dimethyl-1,2-benziodoxole >97.0%(HPLC) 887144-97-0 1g $221 2024-03-01 Buy
TCI Chemical T2624 1-Trifluoromethyl-3,3-dimethyl-1,2-benziodoxole >97.0%(HPLC) 887144-97-0 5g $767 2024-03-01 Buy
Sigma-Aldrich 696641 3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole 95% 887144-97-0 250mg $71.4 2024-03-01 Buy
Product number Packaging Price Buy
696641 5g $342 Buy
696641 1g $442 Buy
T2624 1g $221 Buy
T2624 5g $767 Buy
696641 250mg $71.4 Buy

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent Chemical Properties,Uses,Production

Description

1,3-dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole is in the form of colorless, white solid. It is soluble in all common organic solvents. It is used as effective and very versatile reagent for trifluoromethylation reactions of a variety of compounds including secondary and primary aryland alkylphospines, phenols, peptides containing cysteine residues by SPPS and electrophilic S-trifluoromethylation, arenes and N-heterocycles, and electrophilic N-trifluoromethylation of arozoles.

Reference

J. Charpentier, N. Früh, A. Togni, Electrophilic Trifluoromethylation by use of hypervalent iodine reagents, Chemical Reviews, 2015, vol. 115, pp. 650-682

Chemical Properties

White to light yellow solid

Uses

Togni’s Reagent is used in trifluoromethylation reactions.

Uses

Mild, electrophilic, hypervalent iodine CF3 reagent effective for the trifluoromethylation of a wide range of substrates.

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent synthesis

610-97-9
887144-97-0
Synthesis of 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent from Methyl 2-iodobenzoate

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent Preparation Products And Raw materials

Raw materials

1,2-Benziodoxole, 1-(acetyloxy)-1,3-dihydro-3,3-dimethyl 1-Fluoro-3,3-dimethyl-1,2-benziodoxole 1-Chloro-1,3-dihydro-3,3-diMethyl-1,2-benziodoxole Methyl 2-iodobenzoate 2-(2-iodophenyl)propan-2-ol

Preparation Products

1-Bromo-4-(1-trifluoromethyl-cyclopropyl)-benzene 3-(trifluoroMethyl)pyrazin-2-aMine 4-(TRIFLUOROMETHYL)DIPHENYL ETHER 4-(tert-Butyl)-alpha,alpha,alpha-trifluorotoluene, 1-(tert-Butyl)-4-(trifluoromethyl)benzene 2-[(trifluoromethyl)sulfanyl]phenol

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent Suppliers

Global( 168)Suppliers
Supplier Tel Email Country ProdList Advantage
Springchem New Material Technology Co.,Limited 		+86-021-62885108 +8613917661608 info@spring-chem.com China 2068 57
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15928 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Changzhou Ansciep Chemical Co., Ltd. 		+86 519 86305871 sales@ansciepchem.com CHINA 4242 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 47465 58
Richest Group Ltd 		18017061086 oled@richest-group.com CHINA 5601 58
Supplier Advantage
Springchem New Material Technology Co.,Limited 		57
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
career henan chemical co 		58
Changzhou Ansciep Chemical Co., Ltd. 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Richest Group Ltd 		58

View Lastest Price from 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent pictures 2022-10-10 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent
887144-97-0
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent pictures 2021-07-13 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent
887144-97-0
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent pictures 2021-07-10 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent
887144-97-0
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent Spectrum

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent(887144-97-0)FT-IR

887144-97-0(1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent)Related Search:

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2-IODOISOPROPYLBENZENE Trifluoromethyl iodide 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent

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1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent 1,3-dihydro-3,3-diMethyl-1-(trifluoroMethyl)-1,2-benziodoxole 1,3-Dhydro-3,3-diMethyl-1-(trifluoroMethyl)-1,2-benziodoxole 3,3-DMethyl-1-(trifluoroMethyl)-1,2-benziodoxole 1,3-Dihydro-3,3-diMethyl-1-(trifluoroMethyl)-1,2-b 3,3-DiMethyl-1-(trifluoroMethyl)-1,2-benziodoxole 95% 3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole / TOGNI A 3,3-DiMethyl-1-(trifluoroMethyl)-1,2-benziodoxole (Togni‘s reagent) 3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, >=98% 3,3-Dimethyl-1-(trifluoromethyl)-1,2- benziodoxole (Togni's reagent I) 3,3-Dimethyl-1-(trifluoromethyl)-1,2-benzodioxole 1,2-Benziodoxole,3,3-dimethyl-1-(trifluoromethyl)- 1-Trifluoromethyl-3,3-dimethyl-1,2-benziodoxole, 97%, for synthesis 3,3-dimethyl-1-(trifluoromethyl)-1$l^{3},2-benziodoxole 3,3-dimethyl-1-(trifluoromethyl)-1λ3,2-benziodoxole Togni`s Reagent (3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole) extrapure, 97% 3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole 1-Trifluoromethyl-3,3-dimethyl-1,2-benziodoxole Togni's Reagent Togni Reagent togni's reagent 887144-97-0 C10H10F3IO