ChemicalBook >> CAS DataBase List >>(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester

(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester

CAS No.
149809-43-8
Chemical Name:
(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester
Synonyms
(5R-cis)-Toluene-4-sulfonic acid;((3R,5R)-5-((1H-1,2,4-triazol-1-yl)Methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)Methyl 4-Methylbenzenesulfonate;2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-Methylphenyl)sulfonyl]oxy]Methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol;Posaconazole A;Posaconazole int1;((3S,5R)-5-((1H-1;US-DMF No.: 033193;Posaconazole inter-1;Posaconazole Main Ring;Posaconazole 149809-43-8
CBNumber:
CB22128616
Molecular Formula:
C21H21F2N3O4S
Molecular Weight:
449.47
MDL Number:
MFCD13195567
MOL File:
149809-43-8.mol
MSDS File:
SDS
Last updated:2023-06-08 17:06:34

(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester Properties

Melting point 100-102°C
Boiling point 608.1±65.0 °C(Predicted)
Density 1.40
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility slightly sol. in Chloroform
form powder to crystal
pka 2.75±0.10(Predicted)
color White to Orange to Green
InChIKey DFWVLCJRFGIRAK-HRAATJIYSA-N
CAS DataBase Reference 149809-43-8(CAS DataBase Reference)
FDA UNII LDY4QZP8PB

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08
Signal word  Danger
Hazard statements  H301-H311-H331-H341
Precautionary statements  P201-P202-P261-P264-P270-P271-P280-P302+P352-P304+P340-P308+P313-P310-P330-P361-P403+P233-P405-P501
HS Code  2934.99.4400

(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical D4537 (3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate >98.0%(HPLC) 149809-43-8 1g $457 2021-12-16 Buy
TCI Chemical D4537 (3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate >98.0%(HPLC) 149809-43-8 200mg $123 2024-03-01 Buy
TRC T535900 (5R-cis)-Toluene-4-sulfonicAcid5-(2,4-Difluorophenyl)-5-[1,2,4]triazol-1-ylmethyltetrahydrofuran-3-ylmethylEster 149809-43-8 100mg $790 2021-12-16 Buy
American Custom Chemicals Corporation HCH0029265 (5R-CIS)-TOLUENE-4-SULFONIC ACID 5-(2,4-DIFLUOROPHENYL)-5-(1H-1,2,4-TRIAZOL-1-YL)METHYLTETRAHYDROFURAN-3-YLMETHYL ESTER 95.00% 149809-43-8 100MG $1709.98 2021-12-16 Buy
Ark Pharm P000097815 ((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate 97% 149809-43-8 5g $553 2021-12-16 Buy
Product number Packaging Price Buy
D4537 1g $457 Buy
D4537 200mg $123 Buy
T535900 100mg $790 Buy
HCH0029265 100MG $1709.98 Buy
P000097815 5g $553 Buy

(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester Chemical Properties,Uses,Production

Chemical Properties

White Crystalline Solid

Uses

Posaconazole intermediate. Antifungal agent.

98-59-9
160709-02-4
149809-43-8
Synthesis of (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester from Tosyl chloride and D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)-

(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester Preparation Products And Raw materials

Global( 375)Suppliers
Supplier Tel Email Country ProdList Advantage
Beijing Lianben Pharm-Chemicals Tech. Co.,Ltd
+86-010-83386758 +86-18810831598 jennifer@lianben.com China 85 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 14936 58
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497 sales01@cooperate-pharm.com CHINA 1811 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21700 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
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13867897135 sales@nbinno.com CHINA 925 58
Hangzhou Cyanochem Co., Ltd.
+86 17788583750 sales@cyanochem.com CHINA 283 58
Jinan Finer Chemical Co., Ltd
+86-531-88989536 +86-15508631887 sales@finerchem.com China 2966 58

View Lastest Price from (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester pictures 2024-03-28 (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester
149809-43-8
US $0.00 / kg 25kg 98% Inquiry PNP Biotech Co. Ltd
(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester pictures 2022-11-29 (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester
149809-43-8
US $0.00-0.00 / g 1g ≥98% 1-1000 Changzhou Rokechem Technology Co., Ltd.
main intermediate of Posaconazole pictures 2022-11-03 main intermediate of Posaconazole
149809-43-8
US $0.00 / kg 25kg 99% 20 tons TAIZHOU DKD CHEMICAL CO., LTD.
((3S,5R)-5-((1H-1,2,4-triazol-1-yl)Methyl)-5-(2,4-difluorophenyl)-tetrahydrofuran-3-yl)Methyl 4-Methylbenzenesulfonate Posaconazole InterMediates (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)Methyltetrahydrofuran-3-ylMethyl ester- (POA) (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4 Toluene-4-sulfonica cid 5-(2,4-difluoro-phenyl)-5-[1,2,4]triazol-1-ylMethyl-tetrahydro-furan-3-ylMethyl ester Posaconazole InterMediate Posaconazole inter-1 Posaconazole Main Ring (3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate Posaconazole int1 Posaconazole Intermediate1 Posa-12 ((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate [(3S,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methyl 4-methylbenzenesulfonate ((3S,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)-tetrahydrofuran-3-yl)methyl (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester Posaconazole Tosyl Impurity (3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate > (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydr D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-(1H-1,2,4-triazol-1-yl)- (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl) ((3S,5R)-5-((1H-1,2,4-triazol-1-yl)Methyl)-5-(2,4-difluorophenyl)-tetrahydrofuran-3-yl)Methyl 4-Methylbenzenesulfonate (Posaconazole intermediate) Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester p-Toluenesulfonic Acid (3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl Ester Posaconazole 149809-43-8 (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester ISO 9001:2015 REACH Posaconazole main compound 1 (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1... ((3S,5R)-5-((1H-1 US-DMF No.: 033193 (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofur ((3S,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-Toluene benzenesulfonate (5R-cis)-Toluene-4-sulfonic acid 5-(2 4-triazol-1-yl)Methyltetrahydrofuran-3-ylMethyl ester 4-difluorophenyl)-5-(1H-1 4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl esterChemicalBook Posaconazole Diastereoisomer Related Compound 8 ((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluo (5R-CIS) -Toluene-4-sulfonic acid 5- (2,4-difluorophenyl) -5- (1H-1,2,4-triazol-1-yl) methyl tetrahydrofuran-3- Methyl ester (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)Methyltetrahydrofuran-3-ylMethyl esterChemicalBook [(3S,5R)-5-(2,4-difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-yl]methyl 4-methylbenzene-1-sulfonate Posazonazole intermediate POA Posaconazole Impurity 53 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-Methylphenyl)sulfonyl]oxy]Methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol ((3R,5R)-5-((1H-1,2,4-triazol-1-yl)Methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)Methyl 4-Methylbenzenesulfonate (5R-cis)-Toluene-4-sulfonic acid (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazo 1-yl)methyltetrahydrofuran-3-ylmethyl ester ((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)-tetrahydrofuran-3-yl)methyl 4- (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methy... main intermediate of Posaconazole Posaconazole A (3S,5R)-5-(1,2,4-triazol-1-yl-methyl)-5-(2,4-difluorophenyl)-3-(tosyloxymethyl)tetrahydrofuran Posaconazole Intermediate-A 149809-43-8 C21H21F2N3O4S Aromatics Chiral Reagents Intermediates Intermediates & Fine Chemicals