PI-PLC, 1-Phosphatidyl-D-myo-inositol inositol phosphohydrolase, cyclic-phosphate forming
- CAS No.
- 37288-19-0
- Chemical Name:
- PI-PLC, 1-Phosphatidyl-D-myo-inositol inositol phosphohydrolase, cyclic-phosphate forming
- Synonyms
- PC-PLC;phosphatidylinositol diacylglycerol-lyase;PI-PLC, 1-Phosphatidyl-D-myo-inositol inositol phosphohydrolase, cyclic-phosphate forming;Phospholipase C, Phosphatidylinositol-specific from Bacillus cereus lyophilized powder, >=1,000 units/mg protein (Lowry)
- CBNumber:
- CB22131094
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00131896
- MOL File:
- Mol file
PI-PLC, 1-Phosphatidyl-D-myo-inositol inositol phosphohydrolase, cyclic-phosphate forming price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | P8804 | Phospholipase C, Phosphatidylinositol-specific from Bacillus cereus buffered aqueous glycerol solution, ≥1,000?units/mg protein (Lowry) | 37288-19-0 | 5UNITS | $487 | 2024-03-01 | Buy |
Sigma-Aldrich | P8804 | Phospholipase C, Phosphatidylinositol-specific from Bacillus cereus bufferedaqueousglycerolsolution,≥1,000?units/mgprotein(Lowry) | 37288-19-0 | 25units | $1940 | 2024-03-01 | Buy |
Sigma-Aldrich | P5542 | Phospholipase C, Phosphatidylinositol-specific from Bacillus cereus lyophilizedpowder,≥1,000?units/mgprotein(Lowry) | 37288-19-0 | 5units | $276 | 2024-03-01 | Buy |
Sigma-Aldrich | P5542 | Phospholipase C, Phosphatidylinositol-specific from Bacillus cereus lyophilizedpowder,≥1,000?units/mgprotein(Lowry) | 37288-19-0 | 25units | $942 | 2024-03-01 | Buy |
American Custom Chemicals Corporation | ENZ0000745 | PHOSPHOLIPASE C, PHOSPHATIDYLINOSITOL-SPECIFIC 95.00% | 37288-19-0 | 5MG | $497.71 | 2021-12-16 | Buy |
PI-PLC, 1-Phosphatidyl-D-myo-inositol inositol phosphohydrolase, cyclic-phosphate forming Chemical Properties,Uses,Production
Uses
Phospholipase C, Phosphatidylinositol-specific from Bacillus cereus has been used:
- in the hydrolysis of substrates p-nitrophenylphosphorylcholine (p-NPPC) and p-nitrophenylphosphorylphosphate (p-NPP)
- to cleave glycosylphosphatidylinositol (GPI) anchor of lynx1 protein and its detachment from plasma membrane
- to cleave immunolabeled HeLa cells
Uses
Phospholipase C, Phosphatidylinositol-specific from Bacillus cereus has been used to cleave GPI-anchored protein from green fluorescent protein- glycosylphosphatidylinositol (GFP-GPI) from the cell membrane. It has also been used in invasion assay to test the involvement of PLAP in T. cruzi invasion to human epithelial type 2 (HEp-2) cells.
General Description
Phosphatidylinositol-specific phospholipase C (PI-PLC) from Bacillus cereus is a 298 residual protein. It belongs to the class of ubiquitous enzymes. PI-PLC is characterized with a single globular domain and it folds into eight (βα) barrel sheets, out of which only six βα units are found in barrel, lacking helices between strands IV and V and V and VI.
Biochem/physiol Actions
Used for the release of GPI anchored proteins from the membrane.
PI-PLC, 1-Phosphatidyl-D-myo-inositol inositol phosphohydrolase, cyclic-phosphate forming Preparation Products And Raw materials
Raw materials
Preparation Products
PI-PLC, 1-Phosphatidyl-D-myo-inositol inositol phosphohydrolase, cyclic-phosphate forming Suppliers
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