ChemicalBook >> CAS DataBase List >>2'-deoxy-2'-fluoro-2'-C-methylcytidine

2'-deoxy-2'-fluoro-2'-C-methylcytidine

CAS No.
817204-33-4
Chemical Name:
2'-deoxy-2'-fluoro-2'-C-methylcytidine
Synonyms
ethyl 4-broMo-1-Methyl-1H-pyrrole-2-carboxylate;PSI 6130;R 1656;CS-1995;PSI-6130;PSI 6130;Sofosbuvir Impurity 121;PSI-6130;R 1656;PSI 6130;2'-Deoxy-2'-F-2'-C-methylcytidine;2'-deoxy-2'-Fluoro-2'-methylcytidine;2'-deoxy-2'-fluoro-2'-C-methylcytidin
CBNumber:
CB22525888
Molecular Formula:
C10H14FN3O4
Molecular Weight:
259.23
MDL Number:
MFCD13176566
MOL File:
817204-33-4.mol
MSDS File:
SDS
Last updated:2024-03-22 17:12:53

2'-deoxy-2'-fluoro-2'-C-methylcytidine Properties

Melting point 216-218℃
Boiling point 482.4±55.0 °C(Predicted)
Density 1.67
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Methanol (Slightly), Water (Slightly)
pka 12.86±0.70(Predicted)
form Solid
color White to Light Brown
Stability Hygroscopic
FDA UNII 05J68784G1

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

2'-deoxy-2'-fluoro-2'-C-methylcytidine price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 13575 PSI-6130 817204-33-4 1mg $93 2024-03-01 Buy
Cayman Chemical 13575 PSI-6130 817204-33-4 5mg $321 2024-03-01 Buy
TRC P839680 PSI6130 817204-33-4 25mg $640 2021-12-16 Buy
Matrix Scientific 097930 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one 95+% 817204-33-4 1g $685 2021-12-16 Buy
Biorbyt Ltd orb146167 PSI6130 >99% 817204-33-4 1g $765 2021-12-16 Buy
Product number Packaging Price Buy
13575 1mg $93 Buy
13575 5mg $321 Buy
P839680 25mg $640 Buy
097930 1g $685 Buy
orb146167 1g $765 Buy

2'-deoxy-2'-fluoro-2'-C-methylcytidine Chemical Properties,Uses,Production

Description

PSI-6130 is a nucleoside inhibitor of the NS5B RNA polymerase of hepatitis C virus (HCV; Ki = 4.3 μM). It inhibits HCV genotype 1b (GT-1b) Con1 and GT-1a H77 viral replication in Huh7 replicon cells using a luciferase-based assay (EC50s = 0.51 and 0.30 μM, respectively). PSI-6130 also inhibits replication of HCV GT-1b and GT-1a replicons from clinical isolates, with EC50 values ranging from 0.60 to 1.41 μM, and 0.20 to 0.43 μM, respectively, in the same assay. It has little or no activity against West Nile Virus (WNV), Dengue type 2 virus (DV), human immunodeficiency virus (HIV), or hepatitis B virus (HBV; EC90s = 46.3, >100, >100, and >10 μM, respectively).

Uses

PSI-6130 is an experimental treatment for hepatitis C. PSI-6130 is a member of a class of antiviral drugs known as nucleoside polymerase inhibitors. PSI-6130 inhibits the hepatitis C virus RNA dependant RNA polymerase called NS5B.

target

Hepatitis C Virus Nucleoside

2'-deoxy-2'-fluoro-2'-C-methylcytidine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 124)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 16805 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15932 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Nanjing Baifuli Technology Co., Ltd.
+86-15335185688 sales@unisyn.cn CHINA 332 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49390 58

View Lastest Price from 2'-deoxy-2'-fluoro-2'-C-methylcytidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2'-deoxy-2'-fluoro-2'-C-methylcytidine pictures 2024-03-23 2'-deoxy-2'-fluoro-2'-C-methylcytidine
817204-33-4
US $5.00-0.10 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
2'-deoxy-2'-fluoro-2'-C-methylcytidine pictures 2019-08-06 2'-deoxy-2'-fluoro-2'-C-methylcytidine
817204-33-4
US $5.00 / KG 1KG 99% 1ton Career Henan Chemical Co
(2'R)-2'-deoxy-2'-fluoro-2'-methyl-Cytidine PSI-6130;R 1656;PSI 6130 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyr 2'-deoxy-2'-fluoro-2'-C-methylcytidine R 1656 ethyl 4-broMo-1-Methyl-pyrrole-2-carboxylate 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimi 4-AMino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidin-2(1H)-one R 1656; R-1656; R1656; PSI6130; PSI 6130 2'-deoxy-2'-fluoro-2'-C-methylcytidin 2'-Deoxy-2'-F-2'-C-methylcytidine CS-1995 PSI-6130;PSI 6130 Cytidine, 2'-deoxy-2'-fluoro-2'-methyl-, (2'R)- 2'-deoxy-2'-fluoro-2'-C-methylcytidine,817204-33-4 ethyl 4-broMo-1-Methyl-1H-pyrrole-2-carboxylate PSI 6130 2'-deoxy-2'-Fluoro-2'-methylcytidine 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one (sofosbuvir Impurity) Sofosbuvir Impurity 121 2'-C-methyl-2'-Fluoro-2'-deoxyCytidine 2'-Deoxy-2'-fluoro-2'-C-methylcytidine 817204-33-4 apis