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2-Bromopropionic acid

CAS No.
598-72-1
Chemical Name:
2-Bromopropionic acid
Synonyms
2-BROMOPROPANAMIDE;(S)-2-BROMOPROPANOIC ACID;A-BROMOPROPIONIC ACID;ALPHA-BROMOPROPIONIC ACID;2-broMide;3-(3-(4'2-Bromopropion;-Bromo-[1,1'2-BroMine Propionic;DL-2-Bromopropionic
CBNumber:
CB2260767
Molecular Formula:
C3H5BrO2
Molecular Weight:
152.97
MDL Number:
MFCD00004211
MOL File:
598-72-1.mol
MSDS File:
SDS
Last updated:2023-11-28 16:31:44

2-Bromopropionic acid Properties

Melting point 25.7°C
Boiling point 203 °C (lit.)
Density 1.7 g/mL at 25 °C (lit.)
refractive index n20/D 1.475(lit.)
Flash point 212 °F
storage temp. room temp
form Liquid After Melting
pka pK1: 2.971 (25°C)
color Clear colorless to yellow
Specific Gravity 1.7
Water Solubility soluble
BRN 605451
Dielectric constant 11.0
EWG's Food Scores 1
FDA UNII UE0XVY2DT6
NIST Chemistry Reference 2-Bromopropanoic acid(598-72-1)
EPA Substance Registry System Propanoic acid, 2-bromo- (598-72-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
Signal word  Danger
Hazard statements  H290-H302-H314
Precautionary statements  P280-P301+P312+P330-P303+P361+P353-P305+P351+P338+P310
Hazard Codes  C,Xi,F
Risk Statements  22-34-40-36/37/38-38-11
Safety Statements  26-36/37/39-45-36-16-24-9
RIDADR  UN 3265 8/PG 2
WGK Germany  3
RTECS  UA2451715
TSCA  Yes
HazardClass  8
PackingGroup  II
HS Code  29159080
NFPA 704
1
3 0

2-Bromopropionic acid price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich B78300 2-Bromopropionic acid 99% 598-72-1 1kg $217 2024-03-01 Buy
Sigma-Aldrich 47645 2-Bromopropionic acid solution certified reference material, 1000?μg/mL in methyl tert-butyl ether 598-72-1 1mL $37.2 2022-05-15 Buy
TCI Chemical B0644 2-Bromopropionic Acid >98.0%(GC)(T) 598-72-1 25g $20 2024-03-01 Buy
TCI Chemical B0644 2-Bromopropionic Acid >98.0%(GC)(T) 598-72-1 500g $73 2024-03-01 Buy
Alfa Aesar A17569 2-Bromopropionic acid, 98% 598-72-1 250g $66 2024-03-01 Buy
Product number Packaging Price Buy
B78300 1kg $217 Buy
47645 1mL $37.2 Buy
B0644 25g $20 Buy
B0644 500g $73 Buy
A17569 250g $66 Buy

2-Bromopropionic acid Chemical Properties,Uses,Production

Chemical Properties

clear colorless to yellowish liquid after melting. soluble in water, miscible with alcohol, ether, chloroform and benzene.

Uses

2-Bromopropionic Acid is a versatile reactant used in emulsion polymerization in the preparation of reversible addition-fragmentation chain transfer (RAFT) agent.

Uses

It is employed as pharmaceutical and agrochemical intermediate. It is used as an alkylation agent for mercaptans and other sulfur containing compounds.

Application

2-bromopropionic acid is an organic synthesis intermediate, used in the production of herbicides quizalofop-ethyl, napropamide, fenthiaprop and fungicides metalaxyl, benalaxyl, procymidone, etc., used in the synthesis of pharmaceutical intermediates body alanine.

Preparation

2-Bromopropionic acid is obtained by bromination of propionic acid. Add propionic acid and phosphorus trichloride to the reaction kettle, keep the temperature at 80°C, slowly add bromine to the reaction solution dropwise, and heat up to 85°C after the addition of bromine, and raise the temperature to 100°C when the color of bromine disappears completely, it takes about 2~3h, and then the bromine and hydrobromic acid are recovered under reduced pressure, and then the finished product is obtained by distillation under reduced pressure.

Synthesis Reference(s)

Tetrahedron Letters, 13, p. 4067, 1972 DOI: 10.1016/S0040-4039(01)94239-X

802294-64-0
598-72-1
Synthesis of 2-Bromopropionic acid from Propionic-2,3-14C1 acid (8CI)
Global( 380)Suppliers
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View Lastest Price from 2-Bromopropionic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Bromopropionic acid pictures 2023-10-12 2-Bromopropionic acid
598-72-1
US $0.00 / kg 1kg 0.99 20tons Hebei Yanxi Chemical Co., Ltd.
2-Bromopropionic acid pictures 2023-10-12 2-Bromopropionic acid
598-72-1
US $0.00 / kg 1kg 0.99 20tons Hebei Yanxi Chemical Co., Ltd.
Dl-2-Bromopropionic pictures 2023-03-06 Dl-2-Bromopropionic
598-72-1
US $19.00 / KG 1KG 99.% 10 ton Hebei Guanlang Biotechnology Co,.LTD
RARECHEM AL BO 1266 2-bromo-propanoicaci 2-bromopropionic acid solution DL-2-Bromopropionic D,L-2-BROMOPROPIONIC ACID (+/-)-2-BROMOPROPIONIC ACID 2-BROMOPROPIONIC ACID (R,S)-2-BROMOPROPIONICACID 2-BroMine Propionic DL-2-BroMopropionic acid, 99+% 250GR 2-BROMOPROPIONIC ACID FOR SYNTHESIS YA10760700MB 2-BroMopropi 2-broMide 2-Bromopropion (+/-)-2-Bromopropionic acid purum, >=98.0% (GC) (±)-2-Bromopropionic acid DL-2-Bromopropionic acid 2-bromopropanoicacid 2-bromo-Propanoicacid 2-bromo-propionicaci DL-Bromopropanoicacid Propanoic acid, 2-bromo- Propanoicacid,2-bromo- Propionic acid, 2-bromo- 2-BROMOPROPIONIC ACID, 1X1ML, MTBE 1000U G/ML 2-BROMOPROPIONIC ACID, 99+% 2-BROMOPROPIONIC ACID, 1000MG,NEAT 2-Bromopropionicacid,98% DL-2-Bromopropionic acid, 99+% Salicylamide O-Acetate Sodium Salt 2-Bromopropionic Acid (CAS No. : 598-72-1) ??2-bromo propionic acid? (598-72-1?)?? 2-Bromopropionic Acid > 2-BromopropionicAcidSolution,1,000mg/L,1ml Alpha bromine propionic acid Rac-2-Bromopropionic D3 Acid TIANFU CHEM 598-72-1 2-Bromopropionic acid ALPHA-BROMOPROPIONIC ACID A-BROMOPROPIONIC ACID 2-BROMOPROPANAMIDE (S)-2-BROMOPROPANOIC ACID Propionic Acid Impurity 4 3-(3-(4' -biphenyl]-4-yl)-3-hydroxy-1-phenylpropyl)-4-hydroxy-2H-chromen-2-one -Bromo-[1,1' 2-Bromopropionic Acid, ≥ 98.0% 598-72-1 1009-70-8 CH3CHBrCOOH CH3CH2BrCOOH BrCH2CH2COOH C3H4BrO2 CARBOXYLIC ACID Organic Building Blocks Carboxylic Acids Carbonyl Compounds C1 to C5 Building Blocks Organic acids