ChemicalBook >> CAS DataBase List >>(2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide
(2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide
- CAS No.
- 1218816-71-7
- Chemical Name:
- (2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide
- Synonyms
- SK1-IN-1;SK1 inhibitor 1;SK-1-IN-1,SK1IN1,SK1 IN 1;(2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide;2-Pyrrolidinecarboxamide, N-[(1S)-1-[4-[5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl]phenyl]ethyl]-3-hydroxy-, (2S,3S)-
- CBNumber:
- CB23039551
- Molecular Formula:
- C22H30N4O3
- Molecular Weight:
- 398.5
- MDL Number:
- MFCD31382196
- MOL File:
- 1218816-71-7.mol
Last updated:2023-07-14 17:31:58
(2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-6936 | SK1-IN-1 98.75% | 1218816-71-7 | 1mg | $180 | 2021-12-16 | Buy |
| ChemScene | CS-6936 | SK1-IN-1 98.75% | 1218816-71-7 | 5mg | $420 | 2021-12-16 | Buy |
| ChemScene | CS-6936 | SK1-IN-1 98.75% | 1218816-71-7 | 10mg | $720 | 2021-12-16 | Buy |
| ChemScene | CS-6936 | SK1-IN-1 98.75% | 1218816-71-7 | 25mg | $1440 | 2021-12-16 | Buy |
| ChemScene | CS-6936 | SK1-IN-1 98.75% | 1218816-71-7 | 50mg | $2280 | 2021-12-16 | Buy |
(2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide Chemical Properties,Uses,Production
Biological Activity
SK1-IN-1 is a potent sphingosine kinase 1 (SPHK1) inhibitor with IC50 of 58 nM.
in vivo
SK1-IN-1 demonstrates significant improvement in the intrinsic clearance, particularly against human liver microsomes. It is selected for rat PK studies and demonstrates modest in oral bioavailability with acceptable half-lives in blood circulation demonstrates .
target
IC50: 58 nM (SPHK1)
(2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide Preparation Products And Raw materials
Raw materials
Preparation Products
(2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide Suppliers
Global( 18)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 4009686088 | 3193328036@qq.com | China | 29797 | 68 |
| Angel Pharmatech, Ltd. | 17317130613 | 3358272972@qq.com | China | 3237 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9730 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Shanghai Zeye Biotechnology Co., Ltd. | 021-61998551 13122364865 | sale1@shzysw.net | China | 9763 | 58 |
| Shanghai hongqu biomedical technology co. LTD | 88888888888 | hongquchem@qq.com | China | 5132 | 58 |
| cjbscvictory | 13348960310 13348960310 | 3003867561@qq.com | China | 9946 | 58 |
| Kaifeng Mingren Pharmaceutical Co.,LTD | 0371-65741762 | sales@hasunny.com | China | 2380 | 58 |
(2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide
SK1-IN-1
2-Pyrrolidinecarboxamide, N-[(1S)-1-[4-[5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl]phenyl]ethyl]-3-hydroxy-, (2S,3S)-
SK1 inhibitor 1
SK-1-IN-1,SK1IN1,SK1 IN 1
1218816-71-7