Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>Crocin

Crocin

Crocin Structure
Crocin structure
CAS No.
42553-65-1
Chemical Name:
Crocin
Synonyms
GARDENIN;Crocin A;Crocins;Crocin 1;CROCETIN DIGENTIOBIOSYL ESTER;CROCIN;Crocin-Ⅰ;α-Crocin;CCRIS 7705;Crocin ,98%
CBNumber:
CB2311935
Molecular Formula:
C44H64O24
Molecular Weight:
976.97
MDL Number:
MFCD00017495
MOL File:
42553-65-1.mol
MSDS File:
SDS
Last updated:2023-11-21 17:54:18
Request For Quotation

Crocin Properties

Melting point 186° (effervescence)
Boiling point 1169.0±65.0 °C(Predicted)
Density 1.54±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO (Slightly, Heated), Methanol (Very Slightly, Sonicated)
form Powder
pka 12.20±0.70(Predicted)
color Orange to Very Dark Purple
Merck 14,2589
Stability Light Sensitive
InChIKey OXNHRKGZZFWUQZ-QORFUXSJSA-N
LogP -4.742 (est)
CAS DataBase Reference 42553-65-1
EWG's Food Scores 1
FDA UNII 877GWI46C2

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
Safety Statements  24/25
WGK Germany  3
RTECS  HL7380000
F  1-8-10
HS Code  32129000

Crocin price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 17304 Crocin for microscopy 42553-65-1 1g $58.4 2024-03-01 Buy
Sigma-Aldrich PHL80391 Crocin phyproof? Reference Substance 10MG $187 2024-03-01 Buy
Sigma-Aldrich 17304 Crocin for microscopy 42553-65-1 5g $186 2024-03-01 Buy
TCI Chemical C1527 Crocin (Gardenia Fruits Extract) 42553-65-1 25g $184 2024-03-01 Buy
Cayman Chemical 26337 Crocin/Gardenia Extract 42553-65-1 500mg $32 2024-03-01 Buy
Product number Packaging Price Buy
17304 1g $58.4 Buy
PHL80391 10MG $187 Buy
17304 5g $186 Buy
C1527 25g $184 Buy
26337 500mg $32 Buy

Crocin Chemical Properties,Uses,Production

Introduction

Crocin (crocin) is also known as a-crocin and crocetin. It is a series of ester glycosides combining water-soluble carotenoids crocetin and different sugars. It is one of the main active ingredients of saffron, including crocin -1, crocin -2, crocin -3, crocin-4 and crocetin.It is centrally acting antihypertensive and can prevent atherosclerosis and be of antithrombosis, antiplatelet aggregation, and anti myocardial ischemia.
crocin structure
crocin source

Efficacy and effect

The traditional medicine believes that the stigma croci can dredge and activate the collaterals, remove blood stasis, eradicate depression and relieve swelling and pain. It is mainly used for the treatment of anxiety depression, chest distention, irregular menstruation, postpartum haemorrhage and traumatic injury. The main effective components are crocetin and crocin, which has many pharmacological activities, such as being anti-inflammatory and analgesic, antitumor, antidepressant, hypoglycemic and lowering blood pressure. Because the water solution of stigma croci is bright yellow with sweet smell, it is often used as a food additive and high-grade edible pigment, but also can be used as high dye for silk, cotton and wool products. In recent years, pharmacological researches indicate that stigma croci has good control effect for a variety of diseases, including cancer, coronary heart disease, atherosclerosis and hyperlipidemia.

Pharmacological effects

Crocin has the effect of the anti-inflammation and treatment of soft tissue injury, gall liver protection, anti-tumor and other pharmacological effects. It is widely used in food, medicine, chemical industry and other industries. It is used in the treatment of patients with cardiovascular disease and fatty liver.with good medicinal value.

Description

Crocin/Gardenia Extract is a Gardenia extract that contains crocin I, II, and III, and crocetin, among other compounds.

Chemical Properties

Crocin is a reddish brown needle-like crystal. Slightly odor. Easily soluble in hot water, becomes the orange solution. Slightly soluble in anhydrous ethanol, ether, and other organic solvents. Insoluble in oil. The aqueous solution is weakly acidic or neutral transparent bright yellow, with a maximum absorption wavelength of 442nm. color is almost unaffected by pH value. Light and heat resistance is good in neutral or alkaline, and poor in acidic. Metal ion resistance (except iron, blackened by iron) is good. The coloring of protein is better than that of starch and is not affected by pH (pH4-10).

Uses

Crocin, is a natural carotenoid derived the flowers crocus and gardenia. Crocin has been shown to be a potent antioxidant. It has also been shown to have an antiproliferative action against cancer cells in vitro, and also possessing possible antidepressant properties.

Definition

ChEBI: Crocin-1 is a diester that is crocetin in which both of the carboxy groups have been converted to their gentiobiosyl esters. It is one of the water-soluble yellow-red pigments of saffron and is used as a spice for flavouring and colouring food. Note that in India, the term 'Crocin' is also used by GlaxoSmithKline as a brand-name for paracetamol. It has a role as an antioxidant, a food colouring, a plant metabolite and a histological dye. It is a diester, a disaccharide derivative and a diterpenoid. It is functionally related to a beta-D-gentiobiosyl crocetin and a gentiobiose.

General Description

Crocin (CR) is a water-soluble carotenoid found in Gardenia jasmi-noides Ellis and Crocus sativus (saffron). It has two D-gentiobioside glycosyl esters in its structure. CR is one of the major bioactive compounds of saffron contributing to its red color. A highly unsaturared diterpene dicarboxylic acid ester found in saffron.

Biochem/physiol Actions

Crocin alleviates some ethanol-induced impairments of learning and prevents ethanol-induced inhibition of hippocampal long-term potentiation (LTP), a form of activity-dependent synaptic plasticity that may underly learning and memory. Related CNS effects are specific to the digentiobiose ester; crocetin glucose gentiobiose ester is half as potent, and the diglucose ester has no effect at all.

Crocin Preparation Products And Raw materials

Raw materials

Ethanol Pectin COREOPSISYELLOWEXTRACT

Preparation Products

Crocin Suppliers

Global( 300)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3424 58
Hebei Mojin Biotechnology Co., Ltd 		+8613288715578 sales@hbmojin.com China 12456 58
Henan Bao Enluo International TradeCo.，LTD 		+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2503 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Shanghai Zheyan Biotech Co., Ltd. 		18017610038 zheyansh@163.com CHINA 3620 58
Chengdu Greenpure Biopharma CO.,Ltd 		18283602253 jancyzheng@gcgreenpure.com China 952 58
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Chengdu GLP biotechnology Co Ltd 		028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
Hebei Guanlang Biotechnology Co., Ltd. 		+86-19930503282 alice@crovellbio.com China 8823 58
Supplier Advantage
Chengdu Biopurify Phytochemicals Ltd.
58
Hebei Mojin Biotechnology Co., Ltd 		58
Henan Bao Enluo International TradeCo.，LTD 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Zheyan Biotech Co., Ltd. 		58
Chengdu Greenpure Biopharma CO.,Ltd 		58
career henan chemical co 		58
Chengdu GLP biotechnology Co Ltd 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Hebei Guanlang Biotechnology Co., Ltd. 		58

Related articles

  • Side Effects of crocin
  • Crocin is a carotenoid chemical compound that is present in the flowers crocus and gardenia. This is the chemical mainly respo....
  • Feb 11，2022

View Lastest Price from Crocin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CROCIN pictures 2024-04-24 CROCIN
42553-65-1
 US $3660.00-3600.00 / kg 1kg 99.99% 100Tons Hebei Dangtong Import and export Co LTD
Crocin; Saffron Extract; Gardenia Extract pictures 2024-04-23 Crocin; Saffron Extract; Gardenia Extract
42553-65-1
 US $0.00 / KG 1KG 40%-99% HPLC 1000KG Changsha Staherb Natural Ingredients Co., Ltd.
CROCIN pictures 2023-07-26 CROCIN
42553-65-1
 US $10.00 / kg 1kg 99.99% 50000tons Henan Bao Enluo International TradeCo.，LTD
  • CROCIN pictures
  • CROCIN
    42553-65-1
  • US $3660.00-3600.00 / kg
  • 99.99%
  • Hebei Dangtong Import and export Co LTD
  • CROCIN pictures
  • CROCIN
    42553-65-1
  • US $10.00 / kg
  • 99.99%
  • Henan Bao Enluo International TradeCo.，LTD

Crocin Spectrum

CROCIN(42553-65-1)1HNMR

42553-65-1(Crocin)Related Search:

Croci Stigma Crocin 2 BUTYL-BETA-D-GLUCOPYRANOSIDE 2,3-DIHYDROXYPROPYL METHACRYLATE ETHYL SORBATE
N-HEXYL ACRYLATE PROPYL-CROTONATE 4-Hydroxybutyl acrylate Sorbic acid 4-HYDROXYBUTYL METHACRYLATE
Butyl methacrylate trans,trans-2,4-Heptadienal FEMA 3354 3-ALLYLOXY-1,2-PROPANEDIOL Diethylene glycol monobutyl ether
2-HYDROXYPROPYL ACRYLATE 2,6-DIMETHYL-2,4,6-OCTATRIENE 2,3-DIHYDROXYPROPYL ACRYLATE

1of4

saffron(natural) ucopyranosyl)ester Crocin ,98% CrocinⅡ ,98% Crocin ,96% Crocin,Crocetin digentiobiose ester Crocetin digentiobioside (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-Tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioic acid bis(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl) ester 8,8'-Diapo-ψ,ψ-carotene-8,8'-dioic acid bis(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl) ester 8,8'-Diapo-ψ,ψ-carotene-8,8'-dioic acid bis[6-O-β-D-glucopyranosyl-β-D-glucopyranosyl] ester trans-Crocetin di(β-D-gentiobiosyl) ester Crocin, froM Crocus sativus Crocin for microscopy Saffron, HARLECO? Crocin Crocetin digentibiose ester Crocin (gardenia fruit bis(6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl) 8,8'-diapo-psi,psi-carotenedioate CROCIN:B-D-GLUCOPYRANOSE, 6-O--D-GLUCOPYRANOSYL-, 1,1'-[(ALL-E)-2,6,11,15-TETRAMETHYL-2,4,6,8,10,12,14-HEXADECAHEPTAENEDIOATE], crocetin digentibiose ester bis[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl] (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethylhexadeca-2,4,6,8,10,12,14-heptaenedioate CROCIN(CRUDE)(RG) Crocin (Gardenia Fruits Extract) β-D-Glucopyranose, 6-O-β-D-glucopyranosyl-,1,1'-[(all-E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate] Crocetin digentibiose ester, Crocin BETA-D-GLUCOPYRANOSE, 6-O-BETA-D-GLUCOPYRANOSYL-, 1,1'-[(2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-TETRAMETHYL-2,4,6,8,10,12,14-HEXADECAHEPTAENEDIOATE] B-D-GLUCOPYRANOSE, 6-O-BETA-D-GLUCOPYRANOSYL-, 1,1'-[(ALL-E)-2,6,11,15-TETRAMETHYL-2,4,6,8,10,12,14-HEXADECAHEPTAENEDIOATE] CROCETIN BIS(GENTIOBIOSYL) ESTER CROCIN CROCIN GARDENIA FRUIT EXTRACT Crocin-Ⅰ ALPHA-CROCIN 8,8’-Diapo-4,4-carotenedioicacidbis(6-O-D-glucopyranosyl-D-glucopyranosyl)ester 8,8’-diapo-psi,psi-carotenedioicacid,bis(6-o-beta-d-glucopyranosyl-beta-d-gl Di-gentiobiose ester Crocin - microscopy grade b-D-Glucopyranose, 6-O-b-D-glucopyranosyl-,1,1'-[(2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate Crocin/Gardenia Extract Crocin, from gardenia fruits β-D-Glucopyranose, 6-O-β-D-glucopyranosyl-, 1,1'-[(2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate] (2E,4E,6E,8E,10E,12E,14E)-Bis((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl) 2,6,11,15-tetramethylhexadeca-2,4,6,8,10,12,14-heptaenedioate CROCIN USP/EP/BP α-Crocin CROCIN 42553-65-1 Crocin 1 Crocin A GARDENIN CROCETIN DIGENTIOBIOSYL ESTER Crocins CCRIS 7705 Crocin (Gardenia Fruits Extract)（42553651）,Crocin (Gardenia Fruits Extract)（42553 65 1） Endogenous Metabolite,Crocin I,Crocin,inhibit,Inhibitor Tibetan bonus T 42553-65-1 C44H64O24 C46H68O23 BioChemical Biochemicals and Reagents Natural Dyes