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3-Aminopyrazole

CAS No.
1820-80-0
Chemical Name:
3-Aminopyrazole
Synonyms
1H-PYRAZOL-3-AMINE;3-Bromo-2-chloropyridine-4-carboxylic acid;3(5)-Aminopyrazole;1H-PYRAZOL-3-YLAMINE;NSC 76122;INDIP-021;AKOS B007331;3-PYRAZOLAMINE;3-AMINOPYRAZOL;5-Pyrazolamine
CBNumber:
CB2322586
Molecular Formula:
C3H5N3
Molecular Weight:
83.09
MDL Number:
MFCD00005236
MOL File:
1820-80-0.mol
MSDS File:
SDS
Last updated:2024-04-25 17:59:01

3-Aminopyrazole Properties

Melting point 34-37 °C (lit.)
Boiling point 218 °C/122 mmHg (lit.)
Density 1.0248 (rough estimate)
refractive index 1.5060 (estimate)
Flash point >230 °F
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility soluble in Methanol
pka 15.28±0.10(Predicted)
form Oily Liquid or Crystalline Low Melting Solid
color White to light yellow
Sensitive Air & Light Sensitive
BRN 1618
InChIKey JVVRJMXHNUAPHW-UHFFFAOYSA-N
CAS DataBase Reference 1820-80-0(CAS DataBase Reference)
NCI Dictionary of Cancer Terms 3-AP
NIST Chemistry Reference 3(5)-aminopyrazole(1820-80-0)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H314
Precautionary statements  P260-P270-P280-P301+P312-P303+P361+P353-P305+P351+P338
Hazard Codes  C,Xi
Risk Statements  22-34-36/37/38
Safety Statements  26-36/37/39-45-27
RIDADR  UN 3263 8/PG 2
WGK Germany  3
8-10-23
Hazard Note  Corrosive
HazardClass  IRRITANT
HazardClass  8
PackingGroup 
HS Code  29331990
NFPA 704
1
2 0

3-Aminopyrazole price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 160644 3-Aminopyrazole 98% 1820-80-0 2.5g $88.1 2024-03-01 Buy
Sigma-Aldrich 160644 3-Aminopyrazole 98% 1820-80-0 10g $171 2024-03-01 Buy
TCI Chemical A1859 3-Aminopyrazole >98.0%(GC)(T) 1820-80-0 5g $30 2024-03-01 Buy
TCI Chemical A1859 3-Aminopyrazole >98.0%(GC)(T) 1820-80-0 25g $84 2024-03-01 Buy
Alfa Aesar A14458 3-Amino-1H-pyrazole, 97+% 1820-80-0 1g $33.65 2024-03-01 Buy
Product number Packaging Price Buy
160644 2.5g $88.1 Buy
160644 10g $171 Buy
A1859 5g $30 Buy
A1859 25g $84 Buy
A14458 1g $33.65 Buy

3-Aminopyrazole Chemical Properties,Uses,Production

Chemical Properties

3-Aminopyrazole is Low-Melting Yellow Solid

Uses

3-Aminopyrazole is used in the preparation of heterocyclic compounds of pharamaceutical interest

Uses

Employed in a one-pot synthesis of pyrazolopyrimidines.1

Uses

3-Aminopyrazole was used in the spectroscopic characterization of ferrocenoyl peptides via 1H-NMR spectroscopy. It was also used in the synthesis of:

  • symmetrical dialkylpyrazolo[1,5-a]pyrimidines via condensation with symmetrical β-diketones
  • 3,4-annelated coumarins
  • heterocyclic compounds of pharmaceutical interest
  • pyrazolopyrimidines

General Description

3-Aminopyrazole is a heteroarylamine.

Synthesis

The synthesis of 3-Aminopyrazole is as follows:A solution of 50 mg (0.34 mmol) of 3-oxo-3-phenylpropanenitrile and 11.6 mg (0.36 mmol) of hydrazine and 0.024 mL of acetic acid (0.37 mmol) in 3 mL of anhydrous ethanol was heated at 60° C for 24 hr. The mixture was cooled to ambient temperature and the solvent removed in vacuo. The residue was taken up in ethyl acetate, washed with saturated sodium bicarbonate. The organic layer was washed with brine and dried over MgSO4, filtered and evaporated. The solid residue waswashedwithethyl ether and dried in vacuo to give 45 mg (82%) of 3-phenyl-1H-pyrazol-5-amine.
synthesis of 3-Aminopyrazole

6162-76-1
1820-80-0
Synthesis of 3-Aminopyrazole from cyanoacetaldehyde
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View Lastest Price from 3-Aminopyrazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Aminopyrazole pictures 2024-04-25 3-Aminopyrazole
1820-80-0
US $10.00 / kg 1kg 99.6% 100000 Ouhuang Engineering Materials (Hubei) Co., Ltd
3-Aminopyrazole pictures 2024-04-20 3-Aminopyrazole
1820-80-0
US $1.00 / KG 1KG 99.91% 200000 Ouhuang Engineering Materials (Hubei) Co., Ltd
3-Aminopyrazole pictures 2023-09-06 3-Aminopyrazole
1820-80-0
US $0.00 / KG 1KG 99% 500000kg Hebei Guanlang Biotechnology Co., Ltd.
  • 3-Aminopyrazole pictures
  • 3-Aminopyrazole
    1820-80-0
  • US $10.00 / kg
  • 99.6%
  • Ouhuang Engineering Materials (Hubei) Co., Ltd
  • 3-Aminopyrazole pictures
  • 3-Aminopyrazole
    1820-80-0
  • US $1.00 / KG
  • 99.91%
  • Ouhuang Engineering Materials (Hubei) Co., Ltd
  • 3-Aminopyrazole pictures
  • 3-Aminopyrazole
    1820-80-0
  • US $0.00 / KG
  • 99%
  • Hebei Guanlang Biotechnology Co., Ltd.
3-PYRAZOLAMINE 3-AMINO-1H-PYRAZOLE 3-AMINOPYRAZOLE 5-AMINOPYRAZOLE AKOS B007331 3-Aminopyarazole pyrazol-3-ylamine 3-AMINOPYROZOLE 3-AMINOPYRAZOL 1H-Pyrazol-3-amin 3-Amino-1H-pyrazole 97% 3-AMINOPYRAZOLE,99+% 1H-pyrazole-5-amine 5-amino-1H-pyrazole (5-1H-Pyrazolyl)amine 5-Pyrazolamine 3-Aminopyrazole ,98% 1H-Pyrazol-3-amine, 1H-Pyrazol-5-amine 3-AMinopyrazole, 98% 2.5GR 3-Aminopyrazole,3-Pyrazolamine 1H-pyrazol-3-amine(SALTDATA: FREE) NSC 76122 1H-Pyrazol-5-amine, 3-Amino-1H-pyrazole 3-Amino-1H-pyrazole,97+% 3-AP ( NSC663249) INDIP-021 (916420-28-5) 3-aminopyrazole 3-Aminopyrazole > 3(5)-Aminopyrazole 1H-PYRAZOL-3-AMINE 1H-PYRAZOL-3-YLAMINE 3-Bromo-2-chloropyridine-4-carboxylic acid 1H-Pyrazol-3-amine (9CI, ACI) 1H-pyrazol-3-amine or 3-Amino pyrazole (3-Aminopyrazole) 1820-80-0 1820-80-8 C3H5N3 Pyrazoles Building Blocks C3 to C5 Chemical Synthesis Heterocyclic Building Blocks Pyrazoles Miscellaneous Reagents Heterocyclic Compounds Amines Pyrazoles & Triazoles Bases & Related Reagents Heterocycles Nucleotides Pyrazoles & Triazoles Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines bc0001