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(-)-Corey lactone diol

(-)-Corey lactone diol structure

CAS No.: 32233-40-2

Chemical Name:: (-)-Corey lactone diol

Synonyms: COREY LACTONE DIOL;(3aR,4S,5R,6aS)-5-Hydroxy-4-(hydroxyMethyl)hexahydro-2H-cyclopenta[b]furan-2-one;(3aR,4S,5R,6aS)-(-)-5-Hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one, (-)-Corey lactone;（+）COD;Corinoladiol;Coriolide diol;(-) Corey Lactone;(-)-CoreyLactone>(-)-Corey lactone diol;(-) COREY LACTONE DIOL

CBNumber:: CB2339937

Molecular Formula:: C8H12O4

Molecular Weight:: 172.18

MDL Number:: MFCD00075234

MOL File:: 32233-40-2.mol

MSDS File:: SDS

Last updated:2023-09-21 15:25:22

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(-)-Corey lactone diol Properties

Melting point	117-119 °C(lit.)
Boiling point	262.49°C (rough estimate)
Density	1.2104 (rough estimate)
refractive index	1.4455 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
pka	14.36±0.40(Predicted)
form	Crystalline Powder or Crystals
color	White to beige-brown
optical activity	[α]20/D 44°, c = 1.4 in methanol
InChIKey	VYTZWRCSPHQSFX-GBNDHIKLSA-N
CAS DataBase Reference	32233-40-2(CAS DataBase Reference)
FDA UNII	R78KQ4P7T9

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P305+P351+P338

Safety Statements

24/25

WGK Germany

HS Code

29322090

NFPA 704

	0
1		0

(-)-Corey lactone diol price More Price(40)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	341576	(3aR,4S,5R,6aS)-(?)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one 98%	32233-40-2	1g	$52	2024-03-01	Buy
TCI Chemical	H1418	(-)-Corey Lactone >98.0%(GC)	32233-40-2	1g	$178	2024-03-01	Buy
TCI Chemical	H1418	(-)-Corey Lactone >98.0%(GC)	32233-40-2	200mg	$60	2024-03-01	Buy
Alfa Aesar	H56119	(3aR,4S,5R,6aS)-(-)-Hexahydro-5-hydroxy-4-hydroxymethyl-2H-cyclopenta[b]furan-2-one, 98%	32233-40-2	250mg	$132.65	2024-03-01	Buy
Alfa Aesar	H56119	(3aR,4S,5R,6aS)-(-)-Hexahydro-5-hydroxy-4-hydroxymethyl-2H-cyclopenta[b]furan-2-one, 98%	32233-40-2	1g	$370.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
341576	1g	$52	Buy
H1418	1g	$178	Buy
H1418	200mg	$60	Buy
H56119	250mg	$132.65	Buy
H56119	1g	$370.65	Buy

(-)-Corey lactone diol Chemical Properties,Uses,Production

Chemical Properties

white to beige-brown cryst. powder or crystals

Uses

(-)-Corey Lactone Diol is an intermediate of Iloprost (I267300) and shows inhibitory activity towards β-lactamase. Iloprost (I267300) is a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud''s phenomenon and ischemia.

Uses

(-)-Corey Lactone Diol is an intermediate of Iloprost (I267300) and shows inhibitory activity towards β-lactamase. Iloprost (I267300) is a synthetic analogue of Prostacyclin (PGI2) used to treat pulmo nary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia.

Definition

ChEBI: (-)-corey lactone is a gamma-lactone.

(-)-Corey lactone diol synthesis

Synthesis of (-)-Corey lactone diol from (-)-Corey Lactone Benzoate

(-)-Corey lactone diol Preparation Products And Raw materials

Raw materials

2H-Cyclopenta[b]furan-2-one, 5-(acetyloxy)hexahydro-4-(hydroxymethyl)-, (3aR,4S,5R,6aS)- 117624-93-8 (-)-Corey Lactone Benzoate (3aR,4S,5R,6aS)-4-[(Acetyloxy)methyl]hexahydro-5-hydroxy-2H-cyclopenta[b]furan-2-one ((3aR,4S,6aS)-5-acetoxy-2-oxohexahydro-2H-cyclopenta[b]furan-4-yl)Methyl acetate

Preparation Products

2H-Cyclopenta[b]furan-2-one, hexahydro-4-[(1E)-3-oxo-1-octen-1-yl]-5-[(triethylsilyl)oxy]-, (3aR,4R,5R,6aS)- (+)-Cloprostenol 2H-Cyclopenta[b]furan-4-carboxaldehyde, hexahydro-5-hydroxy-2-oxo-, (3aR,4R,5R,6aS)- (3aR,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E)-3-oxo-1-octen-1-yl]-2H-cyclopenta[b]furan-2-one (-)-Corey lactone 4-phenylbenzoate alcohol

(-)-Corey lactone diol Suppliers

Global( 378)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2503	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
Shanghai finete Pharmaceutical Co., Ltd.	+86-18221039705		CHINA	139	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3012	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58

Supplier	Advantage
CONIER CHEM AND PHARMA LIMITED	58
Hebei Yanxi Chemical Co., Ltd.	58
Henan Bao Enluo International TradeCo.，LTD	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
Shanghai finete Pharmaceutical Co., Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58

View Lastest Price from (-)-Corey lactone diol manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-24	(-)-Corey lactone diol 32233-40-2	US $3850.00 / kg	10kg	99.99%	100Tons	Hebei Dangtong Import and export Co LTD
2024-04-22	(-)-Corey Lactone Diol 32233-40-2	US $0.00 / Kg/Bag	2Kg/Bag	0.98	20 tons	Sinoway Industrial co., ltd.
2024-04-17	(-)-Corey lactone diol 32233-40-2	US $1.10 / g	1g	99.0% min	100 tons min	Shaanxi Dideu Medichem Co. Ltd

(-)-Corey lactone diol
32233-40-2
US $3850.00 / kg
99.99%
Hebei Dangtong Import and export Co LTD

(-)-Corey Lactone Diol
32233-40-2
US $0.00 / Kg/Bag
0.98
Sinoway Industrial co., ltd.

(-)-Corey lactone diol
32233-40-2
US $1.10 / g
99.0% min
Shaanxi Dideu Medichem Co. Ltd

(-)-Corey lactone diol Spectrum

(-)-Corey lactone diol(32233-40-2)¹HNMR (-)-Corey lactone diol(32233-40-2)FT-IR (-)-Corey lactone diol(32233-40-2)Raman

32233-40-2((-)-Corey lactone diol)Related Search:

Pregabalin Levetiracetam 2H-Cyclopenta[b]furan-2-one,hexahydro-5-hydroxy-4-(hydroxymethyl)- (1S,5R)-(-)-2-OXABICYCLO[3.3.0]OCT-6-EN-3-ONE 4-(T-BUTYLDI-ME-SIO-ME)HEXA-H-5-(T-H-PYR AN -2-YLOXY)-CYCLOPENTA(B)FURAN-2-ON, 97

(3aR,4S,5R,6aS)-4-(hydroxyMethyl)-5-(triethylsilyloxy)-hexahydro-cyclopentafuran-2-one N-(2-CARBOXY-4,5-DICHLOROBENZOYL)-(-)-10,2-CAMPHORSULTAM (-)-Corey Lactone Diol 2H-Cyclopenta[b]furan-2-one, hexahydro-4-(hydroxymethyl)-5-[(tetrahydro-2H-pyran-2-yl)oxy]-, (3aR,4S,5R,6aS)- (-)-Corey Lactone Benzoate

BENZOIC ACID (3AR,4S,5R,6AS)-2-OXO-4-TRIETHYLSILANYLOXYMETHYL-HEXAHYDRO-CYCLOPENTA[B]FURAN-5-YL ESTER (-)-Corey lactone 4-phenylbenzoate alcohol (-)-Corey lactone diol

1of3

(-)-COREY LACTONE DIOL,98% (3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY-4--2H-CYCLOPENTA(B)FURAN-2-ONE, (1R)-2β-(Hydroxymethyl)-3α,5α-dihydroxycyclopentane-1α-acetic acid 1,5-lactone (1S,5R,6S,7R)-7-Hydroxy-6-hydroxymethyl-2-oxabicyclo[3.3.0]octan-3-one (3aβ,4S,6aβ)-4β-(Hydroxymethyl)-5α-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one (-)-6beta-Hydroxymethyl-7alpha-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one,98% (+)-6β-Hydroxymethyl-7α-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one (-)-6-β-Hydroxymethyl-7-α-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one ,98% (-) Corey Lactone Alcohol (-)-6beta-HydroxyMethyl-7alpha-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one, 98% 1GR 2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-(hydroxyMethyl)-, (3aR,4S,5R,6aS)- Product NaMe: ()-Corey Lactone Diol (3aR,4S,5R,6aS)-5-hydroxy-4-(hydroxymethyl)-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-one (3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY-4-(HYDROXYMETHYL)-2H-CYCLOPENT A[B]FURAN-2-ONE (3AR,4S,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-(HYDROXYMETHYL)-2H-CYCLOPENTA[B]FURAN-2-ONE (-)-6BETA-HYDROXYMETHYL-7ALPHA-HYDROXY-CIS-2-OXABICYCLO[3.3.0]OCTAN-3-ONE (3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY- 4-HOCH2-2H-CYCLOPENTA(B)FURAN-2-ONE, 98% Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one. (-)-COREY DIOL (COREY LACTONE) (-)-Core\/ lactone diol (-)-Corey lactone diol (-) COREY LACTONE DIOL (-)-Corey lactone diol in stock Factory (-)-Corey's lactone diol (-)-CoreyLactone> (-)-Corey lactone diol USP/EP/BP （+）COD (-)-Corey lactone diol(For export only) (-) Corey Lactone (3aR,4S,5R,6aS)-5-Hydroxy-4-(hydroxyMethyl)hexahydro-2H-cyclopenta[b]furan-2-one (3aR,4S,5R,6aS)-(-)-5-Hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one, (-)-Corey lactone COREY LACTONE DIOL Corinoladiol (-)-6beta-Hydroxymethyl-7alpha-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one Coriolide diol (-) - Cortolactone diol (-)-Corey Diol (Corey Lactone) 32233-40-2 70764-05-7 Lactones Organic Building Blocks Chiral Building Blocks Asymmetric Synthesis Latanoprost Prostaglandins API