ChemicalBook >> CAS DataBase List >>D-(-)-Salicin
D-(-)-Salicin
- CAS No.
- 138-52-3
- Chemical Name:
- D-(-)-Salicin
- Synonyms
- SALICIN;D-SALICIN;SALICOSIDE;WHITE WILLOW;Salicine;Salicylin;SALICIN(RG);SALICIN(SH);Salicin >Salicin CRS
- CBNumber:
- CB2349192
- Molecular Formula:
- C13H18O7
- Molecular Weight:
- 286.28
- MDL Number:
- MFCD00006590
- MOL File:
- 138-52-3.mol
- MSDS File:
- SDS
Last updated:2024-03-11 09:10:21
| Melting point | 196-202 °C |
|---|---|
| Boiling point | 388.65°C (rough estimate) |
| alpha | -61.5 º (c=5, water) |
| Density | 1.4340 |
| refractive index | -62 ° (C=3, H2O) |
| storage temp. | 2-8°C |
| solubility | 36g/l |
| form | Fine Crystalline Powder |
| pka | 12.80±0.70(Predicted) |
| color | White |
| Water Solubility | 36 g/L (15 ºC), 250 g/L (60 ºC) |
| Merck | 14,8324 |
| BRN | 89593 |
| Stability | Stable, but light sensitive. Incompatible with strong oxidizing agents. |
| InChIKey | NGFMICBWJRZIBI-MICYEWLZSA-N |
| LogP | -1.232 (est) |
| CAS DataBase Reference | 138-52-3(CAS DataBase Reference) |
| FDA UNII | 4649620TBZ |
| NIST Chemistry Reference | Salicin(138-52-3) |
| EPA Substance Registry System | .beta.-D-Glucopyranoside, 2-(hydroxymethyl)phenyl (138-52-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H317 | |||||||||
| Precautionary statements | P280-P302+P352 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 43 | |||||||||
| Safety Statements | 36/37-37-24/25-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LZ5901700 | |||||||||
| F | 3-10 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29389090 | |||||||||
| NFPA 704 |
|
D-(-)-Salicin price More Price(69)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S0625 | D-(?)-Salicin ≥99% (GC) | 138-52-3 | 5g | $57.1 | 2024-03-01 | Buy |
| Sigma-Aldrich | 79588 | D-(?)-Salicin analytical standard | 138-52-3 | 100mg | $230 | 2024-03-01 | Buy |
| TCI Chemical | S0003 | Salicin >98.0%(HPLC) | 138-52-3 | 5g | $34 | 2024-03-01 | Buy |
| TCI Chemical | S0003 | Salicin >98.0%(HPLC) | 138-52-3 | 25g | $98 | 2024-03-01 | Buy |
| Alfa Aesar | A16524 | D-(-)-Salicin, 99% | 138-52-3 | 5g | $40.2 | 2024-03-01 | Buy |
D-(-)-Salicin Chemical Properties,Uses,Production
Description
D(-)-Salicin is a traditional medicine which has been known to exhibit anti-inflammation and other therapeutic activities, it can inhibit the LPS-induced inflammation in RAW264.7 cells and mouse models.
Chemical Properties
white crystals or powder
Uses
D-(-)-Salicin has been used:
- to study its in vitro anticoagulant and antiplatelet activities
- as a standard in high performance liquid chromatography method (HPLC) for quantitation of salicin from willow plant
- as a tastant in taste threshold assay
- as a constituent of nutrient agar-salicin medium for selective isolation of Lactobacillus paracasei
Uses
Standard substrate in evaluating enzyme Preparations contg b-glucosidase: Weidenhagen, Z. Ver. Zucker-Ind. 79, 591 (1929).
Uses
analgesic, antipyretic
Uses
H1 antihistamine (nonsedating)
Definition
ChEBI: An aryl beta-D-glucoside that is the beta-D-glucoside of the phenolic hydroxy group of salicyl alcohol.
General Description
Salicin is a non-phenolic glucosidic compound extracted from meadowsweet (Filipendula ulmaria L). It is majorly used as a substitute for quinine. Salicin can be used as a therapeutic for patients suffering from rheumatic fever. Salicin acts a metabolic precursor for salicylic acid. It is a novel phytochemical that exhibits immunological cross functions in plants and humans. Salicin facilitates growth and reproduction in plants. In addition, It also protects plants against biotic and abiotic stress.
Biochem/physiol Actions
D-(?)-Salicin exerts anti-rheumatism and anti-inflammatory activities. It inhibits lipopolysaccharide (LPS) induced inflammation in in vitro and in vivo studies. It regulates different signaling pathways such as nuclear factor kappa B (NF-κB) and mitogen-activated protein kinase (MAPK). It also regulates cytokines concentration such as tumor necrosis factor-alpha(TNF-α), interleukin-1β, interleukin-6, and interleukin-10.
Purification Methods
Crystallise D(-)-salicin from EtOAc, EtOH or water and sublime it at 190-195o/12mm. [Armour et al. J Chem Soc 412 1961, IR: Pearl & Darling J Org Chem 24 731 1959, Beilstein 17 III/IV 2986, 17/7 V 113.]
Synthesis of D-(-)-Salicin from 2-[(Acetyloxy)methyl]phenyl β-D-glucopyranoside 2,3,4,6-tetraacetate
D-(-)-Salicin Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 531)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| Changsha Staherb Natural Ingredients Co., Ltd. | +86-0731-84213302 +8618374838656 | sales@staherb.cn | China | 1025 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12453 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15371 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9352 | 55 |
| Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
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View Lastest Price from D-(-)-Salicin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-09 | D(-)-Salicin 98%HPLC
138-52-3
|
US $200.00 / kg | 1kg | 98% | 10000 | Changsha Staherb Natural Ingredients Co., Ltd. | |
 |
2024-04-09 | D-(-)-Salicin
138-52-3
|
US $0.00 / KG | 1KG | 15%-98% HPLC | 1000KG | Changsha Staherb Natural Ingredients Co., Ltd. | |
 |
2024-03-28 | White Willow Bark Extract
138-52-3
|
US $0.00 / kg | 25kg | 15% | Inquiry | PNP Biotech Co. Ltd |
-
- D(-)-Salicin 98%HPLC
138-52-3
- US $200.00 / kg
- 98%
- Changsha Staherb Natural Ingredients Co., Ltd.
-
- D-(-)-Salicin
138-52-3
- US $0.00 / KG
- 15%-98% HPLC
- Changsha Staherb Natural Ingredients Co., Ltd.
-
- White Willow Bark Extract
138-52-3
- US $0.00 / kg
- 15%
- PNP Biotech Co. Ltd
138-52-3(D-(-)-Salicin)Related Search:
WhiteWillowBarkExtract
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beta-D-Glucopyranoside, 2-(hydroxymethyl)phenyl
beta-d-glucopyranoside,2-(hydroxymethyl)phenyl
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saligeninbeta-d-glucopyranoside
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(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[2-(hydroxymethyl)phenoxy]oxane-3,4,5-triol
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