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2,4,6-Tri-tert-butylphenol

2,4,6-Tri-tert-butylphenol structure

CAS No.: 732-26-3

Chemical Name:: 2,4,6-Tri-tert-butylphenol

Synonyms: 2,4,6-Tris(tert-butyl)phenol;Phenol, 2,4,6-tri-tert-butyl-;P23;Phenol,2,4,6-tri-tert-butyl-;P 23;TM02;CRYA2;NCK5A;Voidox;CDK5P35

CBNumber:: CB2357818

Molecular Formula:: C18H30O

Molecular Weight:: 262.43

MDL Number:: MFCD00008821

MOL File:: 732-26-3.mol

MSDS File:: SDS

Last updated:2023-11-10 14:59:17

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2,4,6-Tri-tert-butylphenol Properties

Melting point	125-130 °C (lit.)
Boiling point	277 °C (lit.)
Density	0.8640
vapor pressure	0.073Pa at 25℃
refractive index	1.5029 (estimate)
Flash point	130 °C
storage temp.	-70°C
solubility	Chloroform (Slightly), DMSO (Slightly, Sonicated)
form	buffered aqueous glycerol solution
pka	12.61±0.40(Predicted)
color	Off-White to Pale Yellow
Water Solubility	insoluble
BRN	1913256
InChIKey	PFEFOYRSMXVNEL-UHFFFAOYSA-N
LogP	7.1 at 35℃
CAS DataBase Reference	732-26-3(CAS DataBase Reference)
FDA UNII	99J2VIC675
NIST Chemistry Reference	Phenol, 2,4,6-tris(1,1-dimethylethyl)-(732-26-3)
EPA Substance Registry System	2,4,6-Tris(tert-butyl)phenol (732-26-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS08,GHS09
Signal word	Danger
Hazard statements	H302-H317-H360D-H373-H410
Precautionary statements	P202-P273-P280-P301+P312-P302+P352-P308+P313
Hazard Codes	F,C,N,Xi,Xn
Risk Statements	11-22-34-50-53-36/37/38-51/53
Safety Statements	26-36/37/39-45-60-61-24/25
RIDADR	UN 2430 8/PG 3
WGK Germany	3
RTECS	SN3570000
F	8-23
HazardClass	9
PackingGroup	III
HS Code	29071990
Toxicity	LD50 oral in rat: 1670mg/kg

2,4,6-Tri-tert-butylphenol price More Price(11)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	T49409	2,4,6-Tri-tert-butylphenol 98%	732-26-3	100g	$126	2024-03-01	Buy
Sigma-Aldrich	SAB4500484	Anti-CRYAB antibody produced in rabbit affinity isolated antibody	732-26-3	100μG	$506	2024-03-01	Buy
Sigma-Aldrich	C0745	CDK5/p25, active, GST tagged human PRECISIO? Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution	732-26-3	10μG	$525	2023-06-20	Buy
Sigma-Aldrich	SAB4500486	Anti-CRYAB antibody produced in rabbit affinity isolated antibody	732-26-3	100μG	$485	2023-01-07	Buy
American Custom Chemicals Corporation	CHM0007865	2,4,6-TRI-TERT-BUTYLPHENOL 95.00%	732-26-3	100G	$2501.06	2021-12-16	Buy

Product number	Packaging	Price	Buy
T49409	100g	$126	Buy
SAB4500484	100μG	$506	Buy
C0745	10μG	$525	Buy
SAB4500486	100μG	$485	Buy
CHM0007865	100G	$2501.06	Buy

2,4,6-Tri-tert-butylphenol Chemical Properties,Uses,Production

Chemical Properties

Solid. Insoluble in water; soluble in most organic solvents. Combustible.

Uses

2,4,6-Tri-tert-butylphenol is an antioxidant; used in preparation method of high-temperature resistant electromagnetic shielding electromagnetic bushing.

Flammability and Explosibility

Non flammable

Purification Methods

Distil the phenol under reduced pressure and/or recrystallise it from n-hexane or several times from 95% EtOH until the EtOH solution is colourless [Balasubramanian & Bruice J Am Chem Soc 108 5495 1986]. It has also been purified by sublimation [Yuan & Bruice J Am Chem Soc 108 1643 1986, Wong et al. J Am Chem Soc 109 3428 1987]. Purification has also been achieved by passage through a silica gel column followed by recrystallisation from n-hexane [Kajii et al. J Phys Chem 91 2791 1987]. [Beilstein 6 III 2094, 6 IV 3539.]

Toxicity evaluation

In order to study the chronic toxicity of 2,4,6-tri-tert-butylphenol (TTBP), groups of 40 Slc: Wistar rats of either sex were fed a diet containing 0, 30, 100, 300, or 1000 ppm of TTBP for up to 24 months. Hematological, biochemical, and histopathological examinations performed periodically revealed slight microcytic anemia, changes in some biochemical parameters relating to liver function, and focal necrosis of liver cells following TTBP administration, and these changes observed in females were more severe than those in males. No neoplastic responses following TTBP administration were noted. Hence, it was concluded that TTBP causes liver injury characterized by focal necrosis with microcytic anemia and elevations of serum phospholipids and cholesterol levels, presumably occurring as secondary effects following the liver injury[1].

References

[1] Matsumoto, Kiyoshi , et al. "Chronic toxicity of 2,4,6-tri-tert-butylphenol in rats." Journal of Toxicological Sciences 16.4(1991):167.

2,4,6-Tri-tert-butylphenol Preparation Products And Raw materials

Raw materials

2-Chloro-2-methylpropane Phenol Aluminum chloride

Preparation Products

3,3',5,5'-TETRA(TERT-BUTYL)[1,1'-BIPHENYL]-4,4'-DIOL 2,6-Di-tert-butyl-p-benzoquinone

2,4,6-Tri-tert-butylphenol Suppliers

Global( 223)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
NANJING PASTEUR ChEMICAL CO.,LTD	+86-18066069912 +86-18066069912	1390310770@qq.com	China	17	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12453	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Chemson Industrial (Shanghai) Co., Ltd.	86-21-65208861- 8007	sales1@chemson.com.cn	CHINA	117	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2966	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8822	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58

Supplier	Advantage
NANJING PASTEUR ChEMICAL CO.,LTD	58
Hebei Mojin Biotechnology Co., Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Chemson Industrial (Shanghai) Co., Ltd.	58
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Jinan Finer Chemical Co., Ltd	58
Hebei Guanlang Biotechnology Co., Ltd.	58
Hubei xin bonus chemical co. LTD	58

View Lastest Price from 2,4,6-Tri-tert-butylphenol manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-19	2,4,6-Tri-tert-butylphenol 732-26-3	US $5.00 / kg	1kg	≥99%	1000mt/year	Jinan Finer Chemical Co., Ltd
2023-11-01	2,4,6-Tri-tert-butylphenol 732-26-3	US $0.00 / kg	1000kg	99.9%	5000 tons	NANJING PASTEUR ChEMICAL CO.,LTD
2023-10-16	2,4,6-Tri-tert-butylphenol 732-26-3	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd

2,4,6-Tri-tert-butylphenol
732-26-3
US $5.00 / kg
≥99%
Jinan Finer Chemical Co., Ltd

2,4,6-Tri-tert-butylphenol
732-26-3
US $0.00 / kg
99.9%
NANJING PASTEUR ChEMICAL CO.,LTD

2,4,6-Tri-tert-butylphenol
732-26-3
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

2,4,6-Tri-tert-butylphenol Spectrum

2,4,6-Tri-tert-butylphenol(732-26-3)¹HNMR 2,4,6-Tri-tert-butylphenol(732-26-3)¹³CNMR 2,4,6-Tri-tert-butylphenol(732-26-3)IR1 2,4,6-Tri-tert-butylphenol(732-26-3)Raman 2,4,6-Tri-tert-butylphenol(732-26-3)ESR

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2,4,6-TRI-TERT-BUTYLPHENOL 2,4,6-tris(1,1-dimethylethyl)-phenol Tributylphenol,96% 2,4,6-Tri-tert-bulylphenol Antioxidant 246 2,4,6-TRI-TERTIARY BUTYL PHENOL ( TTBP ) 2,4,6-Tri-tert-butylphenol,97% 2,4,6-Tri-tert-butylphenol ,98% 2,4,6-Tri-tert-buty 4,6-Tri-tert-butyl phenol 2,4,6-Tri-tert-butylphenol, 97% 50GR 2,4,6-Tri-tert-butylphenol, 97% 5GR 2.4.6-Tri-tert Anti-dJ994E9.1 Anti-RPS17p Anti-CRYAB antibody produced in rabbit CRYA2 Rosenthal fiber component α crystallin B chain α(B)-crystallin Anti-CRYAB antibody produced in goat Anti-Crystallin Tri-tert-butyl phe 2,4,6-Tri-t-butylphenol 2,4,6-Tri-tert-butyl-1-hydroxybenzene 2,4,6-Tri-tert-butylhydroxybenzene Alkofen B P 23 phenol,2,4,6-tris(1,1-dimethylethyl)- TM02 Tri-tert-butylphenol Voidox Anti-CRYAB, N-Terminal antibody produced in rabbit Anti-CRYG2 Anti-CRYGB (86-100) antibody produced in rabbit CDK5/p25, active, GST tagged human CDK5P35 NCK5A Anti-CRYA2 Anti-Crystallin, α B Anti-CTPP2 Anti-HSPB5 2,4,6-Tri-tert-butylphenol 98% 2,4,6-Tri-tert-butylphenol ISO 9001：2015 REACH 2,4,6-tris(tert-Butyl) phenol(2,4,6-TTBP) 2,4,6-Tris(tert-butyl)phenol P23 Phenol, 2,4,6-tri-tert-butyl- Phenol,2,4,6-tri-tert-butyl- 2,4,6-Tritertbutylphenol (25 mg) (2,4,6-Tri-tert-butylphenol) 732-26-3 73-26-3 CH33C3C6H2OH C18H30O Building Blocks Organic Building Blocks Phenols Oxygen Compounds