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| CAS No. | 96829-58-2 |
| Chemical Name: | Orlistat |
| Synonyms: | XENICAL;ORLISTAT;Orlistate;Orlipastat;RO-18-0647;ORLIPASTATUM;Ro 18-0647/002;S,S,S,S-Orlistat;Orlistat (200 mg);Orlistat(synthesis) |
| CBNumber: | CB2431985 |
| Molecular Formula: | C29H53NO5 |
| Formula Weight: | 495.73 |
| MOL File: | 96829-58-2.mol |
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| Orlistat Property |
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| solubility : |
DMSO: 19 mg/mL
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Orlistat Chemical Properties,Usage,Production |
Chemical Properties
Off-White Solid |
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Usage
An antiobesity agent. A pancreatic lipase inhibitor. Antiobesity agent. |
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Biological Activity
Hypolipemic pancreatic, gastric and carboxylester lipase inhibitor. Exhibits no activity at phospholipase A 2 , liver esterase, trypsin and chymotrypsin. Inhibits the thioesterase domain of fatty acid synthase, leading to cell cycle arrest at the G 1 /S boundary in vitro . Prevents the absorption of approximately one third of fat from food and exhibits progastrokinetic, antiobesity and antihypercholesterolemic activity in vivo . |
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| Orlistat Preparation Products And Raw materials |
Raw materials
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Preparation Products
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| Orlistat Suppliers Global( 118)Suppliers |
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(S)-2-FORMYLAMINO-4-METHYL-PENTANOIC ACID (S)-1-[[(2S,3S)-3-HEXYL-4-OXO-2-OXETANYL]METHYL]-DODECYL ESTER
RO-18-0647
(-)-TETRAHYDROLIPSTATIN
ORLISTAT
N-FORMYL-L-LEUCINE (1S)-1-[[(2S,3S)-3-HEXYL-4-OXO-2-OXETANYL]METHYL]DODECYL ESTER
Enzyme Inhibitors by Enzyme
Enzymes, Inhibitors, and Substrates
Enzyme Inhibitors
XENICAL
L to O
Lipase, Pancreatic
BioChemical
Biochemicals and Reagents
96829-58-2
(-)-Tetrahydrolipstatin(EquivalentToOrlistat)
C29H53NO5
Orlipastat
Xenical, (-)-Tetrahydrolipstatin, N-Formyl-L-leucine (1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl Ester,
Orlistate
Pharmaceutical Raw Materials
Orlistat, Tetrahydolipstat
ORLIPASTATUM
Miscellaneous Biochemicals
(-)-Tetrahydrolipstatin
API
Antiobesity Agent
C25H53NO3
Ro 18-0647/002
Chiral Reagents
Intermediates & Fine Chemicals
Pharmaceuticals
(-)-Tetrahydrolipstatin, Ro-18-0647, N-Formyl-L-leucine (1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester
L-Leucine, N-formyl-, (1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester
N-Formyl-L-leucine (1S)-1-[[(2S)-3α-hexyl-4-oxooxetan-2β-yl]methyl]dodecyl ester
N-Formyl-L-leucine (S)-1-[[(2S)-3α-hexyl-4-oxooxetane-2β-yl]methyl]dodecyl ester
Orlistat,()-Tetrahydrolipstatin, N-Formyl-L-leucine (1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester, Ro-18-0647
Orlistat (200 mg)
ORLISTAT (BULK MATERIAL)
ORLISTAT PELLETS 50%
Amino Acids & Derivatives
Heterocycles
Orlistat(synthesis)
Orlistat(FerMentation)
(S)-2-FORMYLAMINO-4-METHYL-PENTANOIC ACID (S)-1-[[(2S,3S)-3-HEXYL-4-OXO-2-OXETANYL]METHYL]-DODECYL ESTER
S,S,S,S-Orlistat
(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl (2S)-2-forMaMido-4-Methylpentanoate
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