ChemicalBook >> CAS DataBase List >>SPDP
SPDP
- CAS No.
- 68181-17-9
- Chemical Name:
- SPDP
- Synonyms
- SPDP;SPDP NHS ester;SPDP Crosslinker;3-(2-PYRIDYLDITHIO)-PROPIONIC ACID-OSU;SUCCINIMIDYL 3-(2-PYRIDYLDITHIO)PROPIONATE;N-SUCCINIMIDYL 3-[2-PYRIDYLDITHIO]PROPIONATE;3-(Pyridin-2-yldisulfanyl)-propionic acid-OS;3-(PYRIDIN-2-YLDISULFANYL)-PROPIONIC ACID-OSU;N-SUCCINIMIDYL-3-(2-PYRIDYLDITHIO)PROPIONANATE;N-[3-(2-Pyridyldithio)propionyloxy]succinimide
- CBNumber:
- CB2446059
- Molecular Formula:
- C12H12N2O4S2
- Molecular Weight:
- 312.36
- MDL Number:
- MFCD00009636
- MOL File:
- 68181-17-9.mol
- MSDS File:
- SDS
Last updated:2024-03-27 16:40:14
| Melting point | 84-86 °C(lit.) |
|---|---|
| Boiling point | 465.9±55.0 °C(Predicted) |
| Density | 1.48±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | acetone: 50 mg/mL |
| form | powder |
| pka | 1.76±0.19(Predicted) |
| color | White to Light Yellow |
| BRN | 1548137 |
| Stability | Hygroscopic, Moisture Sensitive |
| InChIKey | JWDFQMWEFLOOED-UHFFFAOYSA-N |
| CAS DataBase Reference | 68181-17-9(CAS DataBase Reference) |
| FDA UNII | 2OHG8V08NL |
SPDP price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P3415 | 3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester ≥95%, powder | 68181-17-9 | 5mg | $67.1 | 2024-03-01 | Buy |
| Sigma-Aldrich | P3415 | 3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester ≥95%, powder | 68181-17-9 | 25mg | $205 | 2024-03-01 | Buy |
| TCI Chemical | S0819 | N-Succinimidyl 3-(2-Pyridyldithio)propionate | 68181-17-9 | 250MG | $174 | 2024-03-01 | Buy |
| TCI Chemical | S0819 | N-Succinimidyl 3-(2-Pyridyldithio)propionate >98.0%(HPLC) | 68181-17-9 | 1g | $390 | 2024-03-01 | Buy |
| TCI Chemical | S0819 | N-Succinimidyl 3-(2-Pyridyldithio)propionate >98.0%(HPLC) | 68181-17-9 | 100mg | $75 | 2021-12-16 | Buy |
SPDP Chemical Properties,Uses,Production
Description
SPDP NHS ester is a heterobiofunctional crosslinker which can react with amine and sulfhydryl groups. SPDP NHS esters are membrane permeable therefore allowing them to funtion inside of cells.
Chemical Properties
White Solid
Uses
Important crosslinking reagent for the preparation of protein-protein and peptide-protein conjugates linked by disulfide bonds.
Uses
A heterobifunctional cross-linker
Uses
3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester (SPDP) is useful for the preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.
It has been used for antibody conjugation and as a protein cross-linker.
General Description
3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester (SPDP) is a heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. It is typically coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thiol-disulfide exchange buffered at pH 8.0 (7.5-8.5). Alternately, this reagent may be used as a protected thiolating reagent following initial coupling and reduction of linker. It incorporates four atom linker.
SPDP Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 227)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4242 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21149 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10326 | 58 |
| HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 | ada@ipurechemical.com | CHINA | 3465 | 58 |
| WinWin Chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 13854 | 58 |
| Alfa Chemistry | info@alfa-chemistry.com | United States | 2344 | 58 |
View Lastest Price from SPDP manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-27 | SPDP-NHS ester
68181-17-9
|
US $0.00 / g | 10g | >99.00% | 10g | Xian confluore Biological Technology Co., Ltd. | |
 |
2019-07-11 | SPDP
68181-17-9
|
US $1.00 / KG | 1KG | 99% | 25kg | Career Henan Chemical Co |
-
- SPDP-NHS ester
68181-17-9
- US $0.00 / g
- >99.00%
- Xian confluore Biological Technology Co., Ltd.
-
- SPDP
68181-17-9
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
68181-17-9(SPDP)Related Search:
3-(2-PYRIDYLDITHIO)PROPIONIC ACID N-HYDROXY-SUCCINIMIDE ESTER
3-(2-PYRIDYLDITHIO)PROPIONIC ACID N-SUCCINIMIDYL ESTER
3-(2-PYRIDYLDITHIO)-PROPIONIC ACID-OSU
succinimidyl3-(2-pyridyldithio)propionate(spdp)
SUCCINIMIDYL 3-(2-PYRIDYLDITHIO)PROPIONATE
SPDP
N-SUCCINIMIDYL-3-(2-PYRIDYLDITHIO)PROPIONANATE
N-SUCCINIMIDYL 3-[2-PYRIDYLDITHIO]PROPIONATE
1-[1-oxo-3-(2-pyridyldithio)propoxy]pyrrolidine-2,5-dione
2,5-Pyrrolidinedione, 1-1-oxo-3-(2-pyridinyldithio)propoxy-
3-(2-PYRIDYLDITHIO)-PROPIONIC ACID N-HYDROXYSUCCINIMIDE ESTER CRYSTALLINE
3-(Pyridin-2-yldisulfanyl)-propionic acid-OS
3-(PYRIDIN-2-YLDISULFANYL)-PROPIONIC ACID-OSU
3-(2-PYRIDYLDITHIO)PROPIONIC ACID*N-HYDR OXYSUCCINIM
3-(2-Pyridyldithio)propionic Acid N-Succinimidyl Ester
SPDP
3-(Pyridin-2-yldisulfanyl)-propionic acid-OSu, SPDP
3-(2-Pyridylthio)propionic acid N-hydroxysucciniMide ester
N-Succinimidyl 3-(2-Pyridyldithio)propionate
SPDP Crosslinker
2,5-dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)propanoate
3-(2-Pyridyldithio)propionic acidN-hydroxyuccinimide ester≥ 97% (HPLC)
N-Succinimidyl 3-(2-pyridyldithio)propionate, SPDP
1-[1-Oxo-3-(2-pyridinyldithio)propyloxy]-2,5-pyrrolidinedione
3-(2-Pyridyldithio)propionic acid 2,5-dioxo-1-pyrrolidinyl ester
3-[(2-Pyridinyl)dithio]propionic acid succinimidyl ester
3-[(2-Pyridyl)dithio]propionic acid succinimidyl ester
N-[3-(2-Pyridyldithio)propionyloxy]succinimide
2,5-dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfaneyl)propanoate
3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester（SPDP）
N-Succinimidyl3-(Pyridin-2yldithio)-propionate(SPDP)
N-Succinimidyl3-(2-Pyridyldithio)propionate>
Propanoic acid, 3-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester
3-(2-Pyridyldithio)propionic Acid N-Hydroxysuccinimide Ester (SPDP Crosslinker) extrapure, 95%
3-(Pyridin-2-yldisulfanyl)propionic acid N-Hydroxy succinimide ester
SPDP NHS ester
2,5-Dioxo-1-pyrrolidinyl 3-(2-Pyridyldisulfanyl)propanoate
68181-17-9
C12H12N2O4S2
BioChemical
Heterobifunctional Cross-Linking Reagents
Crosslinking
Protein Modification
Proteomics
Proteomics and Protein Expression
Heterobifunctional Crosslinker
heteroXlink
Cross Linking Reagents
Nitric Oxide Reagents