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(+/-)-BAY K 8644

(+/-)-BAY K 8644 Structure
(+/-)-BAY K 8644 structure
CAS No.
93468-89-4
Chemical Name:
(+/-)-BAY K 8644
Synonyms
BAY K-8644 (+/-);(+/-)-BAY K 8644;(±)-Bay K 8644 - CAS 93468-89-4 - Calbiochem;(+)-(S)-1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-trifluoromethylphenyl)pyridine-5-carboxylic acid;1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-[TRIFLUOROMETHYL]PHENYL)PYRIDINE-3-CARBOXYLIC ACID METHYL ESTER;1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID, METHYL ESTER;1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2'-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID METHYL ESTER
CBNumber:
CB2471785
Molecular Formula:
C16H15F3N2O4
Molecular Weight:
356.3
MDL Number:
MFCD00036697
MOL File:
93468-89-4.mol
Last updated:2023-05-04 17:34:43
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(+/-)-BAY K 8644 Properties

Melting point 166-172 °C
storage temp. 2-8°C
solubility DMSO: 184 mg/mL
form Yellow solid

SAFETY

Risk and Safety Statements

Hazard Codes  Xi
Risk Statements  36/38
Safety Statements  26-36
WGK Germany  3

(+/-)-BAY K 8644 Chemical Properties,Uses,Production

Definition

ChEBI: Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate is a pentasubstituted dihydropyridine carrying methoxycarbonyl, 2-(trifluoromethyl)phenyl and nitro substituents at positions 3, 4 and 5 respectively as well as two methyl substituents at positions 2 and 6. It is a dihydropyridine, a methyl ester, a C-nitro compound and a member of (trifluoromethyl)benzenes.

General Description

Synthetic dihydropyridine derivative that acts as an active Ca2+ slow channel agonist in neuroendocrine, muscle, thyroid and other cell types. Prolongs single channel open time without affecting the close time. An L-type Ca2+ channel agonist. Composed of two optical isomers. The (-)-enantiomer has strong vasoconstrictive, positive inotropic, and Ca2+ agonistic properties, whereas the (+)-enantiomer has weakly vasodilating, negative inotropic, and Ca2+ antagonistic properties. The net effect of the racemic mix is that of the negative enantiomer. Promotes β-cell proliferation/regeneration.

Biochem/physiol Actions

Primary TargetL-type Ca2+ channel

(+/-)-BAY K 8644 Preparation Products And Raw materials

Raw materials

Preparation Products

(+/-)-BAY K 8644 Suppliers

Global( 64)Suppliers
Supplier Tel Email Country ProdList Advantage
Career Henan Chemica Co 		+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994 2853530910@QQ.com China 8018 62
Chuzhou KeMail Chemical Technology Co., Ltd 0550-5196001 15000891977 wj520wjxby@126.com China 1831 55
ShangHai ChuanQian Chemcial Technique Centre 15869524721 3525679403@qq.com China 3961 58
Shanghai Universal Biotech Co.,Ltd 18768175414 gaojun@univ-bio.com China 24998 58
Supplier Advantage
Career Henan Chemica Co 		58
Zhejiang J&C Biological Technology Co.,Limited 		58
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
ShangHai Biochempartner Co.,Ltd 62
Chuzhou KeMail Chemical Technology Co., Ltd 55
ShangHai ChuanQian Chemcial Technique Centre 58
Shanghai Universal Biotech Co.,Ltd 58

93468-89-4((+/-)-BAY K 8644)Related Search:

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(RS)-BAY K 8644,(+/-)-BAY K 8644,BAY K-8644 (+/-),(+/-)-BAY K8644 CALCIUM SLOW CHANNEL (+-)-CAGED BAY K 8644

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1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2'-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID METHYL ESTER 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID, METHYL ESTER 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-[TRIFLUOROMETHYL]PHENYL)PYRIDINE-3-CARBOXYLIC ACID METHYL ESTER (+/-)-BAY K 8644 BAY K-8644 (+/-) (+)-(S)-1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-trifluoromethylphenyl)pyridine-5-carboxylic acid (±)-Bay K 8644 - CAS 93468-89-4 - Calbiochem 93468-89-4 BioChemical Biochemicals and Reagents Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Type Enzyme Inhibitors Substrate Analogs