ChemicalBook >> CAS DataBase List >>DL-PENICILLAMINE
DL-PENICILLAMINE
- CAS No.
- 52-66-4
- Chemical Name:
- DL-PENICILLAMINE
- Synonyms
- DL-PEN;dl-valin;NSC 22880;NSC 44656;D,L-Pen-OH;H-DL-Pen-OH;AKOS NCG1-0051;DL-PENCILLAMINE;b-Mercaptovaline;DL-PENICILLAMINE
- CBNumber:
- CB2488772
- Molecular Formula:
- C5H11NO2S
- Molecular Weight:
- 149.21
- MDL Number:
- MFCD00004856
- MOL File:
- 52-66-4.mol
Last updated:2023-05-18 11:31:08
| Melting point | 204-208 °C(lit.) |
|---|---|
| Boiling point | 251.8±35.0℃ (760 Torr) |
| Density | 1.204±0.06 g/cm3 (20 ºC 760 Torr) |
| refractive index | 1.5216 (estimate) |
| Flash point | 106.1±25.9℃ |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | Methanol (Slightly), Water (Soluble) |
| pka | pK: 1.8 (carboxyl); 7.9 (a-amino); 10.5 (b-thiol) |
| form | solid |
| Water Solubility | Soluble in ethanol, hot water and sodium hydroxide. |
| Merck | 14,7088 |
| BRN | 2039817 |
| CAS DataBase Reference | 52-66-4(CAS DataBase Reference) |
| FDA UNII | 2XOP7Y1H98 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338-P280h | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38-40-20/21/22 | |||||||||
| Safety Statements | 26-36-22 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | YV9445000 | |||||||||
| HS Code | 29309099 | |||||||||
| Toxicity | LD50 orally in rats: 365 mg/kg (Jaffe) | |||||||||
| NFPA 704 |
|
DL-PENICILLAMINE price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | P0025 | DL-Penicillamine >98.0%(T) | 52-66-4 | 1g | $71 | 2021-12-16 | Buy |
| Alfa Aesar | B24710 | DL-Penicillamine, 97+% | 52-66-4 | 1g | $30.65 | 2024-03-01 | Buy |
| Alfa Aesar | B24710 | DL-Penicillamine, 97+% | 52-66-4 | 5g | $85.1 | 2024-03-01 | Buy |
| Alfa Aesar | B24710 | DL-Penicillamine 97+% | 52-66-4 | 25g | $281 | 2023-06-20 | Buy |
| TRC | P223010 | DL-Penicillamine | 52-66-4 | 1g | $85 | 2021-12-16 | Buy |
DL-PENICILLAMINE Chemical Properties,Uses,Production
Application in Rheumatic Arthritis
Penicillamine onset may be seen in 1 to 3 months, and most responses occur within 6 months. Early adverse effects include skin rash, metallic taste, hypogeusia, stomatitis, anorexia, nausea, vomiting, and dyspepsia. Glomerulonephritis may occur, which manifests as proteinuria and hematuria. Penicillamine is usually reserved for patients who are resistant to other therapies because of the rare but potentially serious induction of autoimmune diseases (e.g., Goodpasture’s syndrome, myasthenia gravis).
Chemical Properties
white to almost white crystalline powder
Uses
antirheumatic, chelating agent (copper), Wilson's desease treatment
Uses
DL-Penicillamine is a penicillin metabolite used in the treatment of Wilson’s disease, Cystinuria, Scleroderma and arsenic poisoning.
Definition
ChEBI: An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Safety Profile
Poison by ingestion and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx.
DL-PENICILLAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 170)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 6992 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| WinWin Chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 13854 | 58 |
| GL Biochem (Shanghai) Ltd. | +86-021-61263370 +86-18901917034 | CHINA | 3904 | 58 | |
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 | mcbio_sales@163.com | China | 2255 | 58 |
View Lastest Price from DL-PENICILLAMINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-28 | L-(+)-Penicillamine
52-66-4
|
US $0.00 / KG | 25KG | 98% | Inquiry | PNP Biotech Co. Ltd | |
 |
2020-02-05 | DL-PENICILLAMINE
52-66-4
|
US $1.00 / KG | 1KG | 98-99.9% | 100kg | Career Henan Chemical Co |
-
- L-(+)-Penicillamine
52-66-4
- US $0.00 / KG
- 98%
- PNP Biotech Co. Ltd
-
- DL-PENICILLAMINE
52-66-4
- US $1.00 / KG
- 98-99.9%
- Career Henan Chemical Co
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NSC 22880
NSC 44656
Valine, 3-mercapto- (9CI)
Valine, 3-mercapto-, DL- (8CI)
β,β-Dimethyl-DL-cysteine, DL-2-Amino-3-mercapto-3-methylbutanoic acid
(±)-3,3-Dimethylcysteine
(±)-3-Mercaptovaline
β-Mercapto-DL-valine
DL-PenicillaMine, 97+%
DL-beta,beta-Dimethylcysteine
DL-beta-Mercaptovaline
D-PENICILLAMINE DL
BETA-MERCAPTO-DL-VALINE
BETA, BETA-DIMETHYL-DL-CYSTEINE
DL-2-AMINO-3-MERCAPTO-3-METHYLBUTANOIC ACID
DL-PENICILLAMINE
DL-β-Mercaptovaline
3,3-DIMETHYL-DL-CYSTEINE
DL-Penicillamine>
Valine, 3-mercapto-
DL-Penicillajnine
D,L-Pen-OH
H-DL-Pen-OH
DL-PEN
DL- Penicillamine racemic
52-66-4
CH32CSHCHNH2COOH
AMINE
Radiopharmaceutical Chemistry (Chelating Reagents)
Ligands for Pharmaceutical Research
Specialty Synthesis
Unnatural Amino Acid Derivatives
Peptide Synthesis
Amino Acids
Antibiotics
Analytical Chemistry
Biochemistry
Ligands for Pharmaceutical Research