Ipamorelin
- CAS No.
- Chemical Name:
- Ipamorelin
- Synonyms
- AIB-HIS-D-NAL(2)-D-PHE-LYS-NH2
- CBNumber:
- CB2664044
- Molecular Formula:
- C38H49N9O5
- Molecular Weight:
- 711.85
- MDL Number:
- MFCD02179658
- MOL File:
- Mol file
InChIKey | NEHWBYHLYZGBNO-BVEPWEIPSA-N |
---|---|
SMILES | C12C=CC=CC=1C=CC(C[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N)CCCCN)CC1C=CC=CC=1)NC(=O)[C@@H](NC(=O)C(N)(C)C)CC1N=CNC=1)=C2 |
FDA UNII | Y9M3S784Z6 |
NCI Drug Dictionary | ipamorelin |
Ipamorelin Chemical Properties,Uses,Production
Description
Ipamorelin Synthetic is a single, non-glycosylated polypeptide chain containing 4 amino acids. Ipamorelin is a pentapeptide (Alb-His-D-2-Nal-D-Phe-Lys-NH2) and a ghrelin mimetic with growth hormone (GH) releasing activity. Ipamorelin mimics ghrelin and binds to the ghrelin receptor (or GH secretagogue receptor, GHSR) in the brain, thereby selectively stimulating the release of GH from the pituitary gland. This results in increased plasma GH levels, which would affect many biological processes. Besides its presence in the brain, GHSR can also be found in the gastrointestinal tract, heart, lung, liver, kidney, pancreas, adipose tissue and immune cells. Unlike the other GH releasing peptides, Ipamorelin only stimulates GH release in a manner very similar to that of growth hormone releasing hormone.
Uses
Ipamorelin is a metabolite of growth hormone releasing peptides (GHRPs). Ipamorelin is a pentapeptide with strong growth hormone releasing potency that evokes insulin release from pancrease of normal and diabetic rats.
Side effects
Ipamorelin appears to have a significant influence on the GI system, adiposity, and overall body composition when administered to test subjects. However, it also produces some direct and indirect side effects. Below, we will examine the most common side effects associated with ipamorelin.
Light headedness
Headaches
Increased prolactin level
Redness, itching, pain, rashes, and sensitivity at the site of injection
Dry mouth
Nausea
Fever (that is transient, and goes away quickly)
Mode of action
Ipamorelin is a pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) and a ghrelin mimetic with growth hormone (GH) releasing activity. Ipamorelin mimics ghrelin and binds to the ghrelin receptor (or GH secretagogue receptor, GHSR) in the brain, thereby selectively stimulating the release of GH from the pituitary gland. This results in increased plasma GH levels, which would affect many biological processes. Besides its presence in the brain, GHSR can also be found in the gastrointestinal tract, heart, lung, liver, kidney, pancreas, adipose tissue and immune cells. Unlike other GH releasing peptides, ipamorelin only stimulates GH release in a manner very similar to that of growth hormone releasing hormone.
Ipamorelin Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Zhuzhou Yaozhijie Chemical Co., LTD | +8618073316972 | sales@goodpeptides.com | China | 244 | 58 |
Hubei Lange Biotechnology Co., Ltd. | +8617762501948 | sales2@langebiotech.com | China | 154 | 58 |
Zhuzhou New Peptides Tech Co.,Ltd. | +8618073326374 | sales@goodpeptides.com | China | 140 | 58 |
.GZ HONESTCHEM CO.,LTD | +86-15013270415 | honestchemical@foxmail.com | China | 247 | 58 |
Qiuxian Baitai New Material Co., LTD | +8618330912755 | sale2@hbyalin.com | China | 1677 | 58 |
Hebei Zhanyao Biotechnology Co. Ltd | 15369953316 +8615369953316 | admin@zhanyaobio.com | China | 2136 | 58 |
Zhengzhou Hanke Import and export Trade Co. LTD | +8613838064731 | sales1@zzybchem.com | China | 66 | 58 |
Shenzhen Sendi Biotechnology Co.Ltd. | 0755-23311925 18102838259 | Abel@chembj.com | CHINA | 3191 | 55 |
Chemsky(shanghai)International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
Shenzhen Simeiquan Biotechnology Co. Ltd | 18126413629 0755-23311925 2355327053 | abel@ycgmp.com | China | 5115 | 58 |
Related articles
- Side effects of Ipamorelin
- Ipamorelin (INN) (developmental code name NNC 26-0161) is a peptide selective agonist of the ghrelin/growth hormone secretagog....
- Apr 11,2022
View Lastest Price from Ipamorelin manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2023-04-13 | Ipamorelin | US $2.00-1.60 / mg | 2mg | 99.99% | 20kg | Zhuzhou New Peptides Tech Co.,Ltd. | ||
2021-11-15 | ipamorelin | US $2.50 / mg | 1kit | 99% | 500000 vial/Month | Qiuxian Baitai New Material Co., LTD | ||
2021-10-28 | Ipamorelin | US $15.00 / BOX | 10BOX | 98%min | 2000 boxes | Zhengzhou Hanke Import and export Trade Co. LTD |
- Ipamorelin
- US $2.00-1.60 / mg
- 99.99%
- Zhuzhou New Peptides Tech Co.,Ltd.
- ipamorelin
- US $2.50 / mg
- 99%
- Qiuxian Baitai New Material Co., LTD
- Ipamorelin
- US $15.00 / BOX
- 98%min
- Zhengzhou Hanke Import and export Trade Co. LTD