BACE-1
- CAS No.
- 158736-49-3
- Chemical Name:
- BACE-1
- Synonyms
- ASP-2;BACE-1;MEMAPSIN-2;B-SECRETASE;HUMAN BACE-1;β-Secretase human;HUMAN BETA-SECRETASE;BETA-SECRETASE HUMAN;BETA-SECRETASE ENZYME;β-secretase precursor
- CBNumber:
- CB2730309
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD03702801
- MOL File:
- Mol file
Last updated:2023-04-23 13:52:06
BACE-1 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S4195 | β-Secretase human recombinant, expressed in HEK 293 cells (C-terminal FLAG tagged), extracellular domain, ≥10,000?units/mg protein, ≥90% (SDS-PAGE), buffered aqueous solution | 158736-49-3 | 50μG | $373 | 2023-06-20 | Buy |
| Sigma-Aldrich | SAB2900193 | Anti-BACE1 (AB1) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 158736-49-3 | 50μg | $599 | 2022-05-15 | Buy |
| Usbiological | 382026 | BACE1 | 158736-49-3 | 96Tests | $729 | 2021-12-16 | Buy |
| Usbiological | 382027 | BACE1 | 158736-49-3 | 96Tests | $729 | 2021-12-16 | Buy |
| Usbiological | 382028 | BACE1 | 158736-49-3 | 96Tests | $729 | 2021-12-16 | Buy |
BACE-1 Chemical Properties,Uses,Production
Uses
Human β-secretase or BACE1 has been used to study the binding reaction between amyloid precursor protein and β-secretase. It has also been used in BACE1 assay.
Biochem/physiol Actions
BACE1 (β-site APP-cleaving enzyme 1) is a transmembrane aspartyl protease responsible for cleaving the amyloid precursor protein (APP). BACE1-mediated cleavage of amyloid precursor protein (APP) is the first step during the generation of pathogenic amyloid-β peptides, hence making it the major drug target for Alzheimer′s disease (AD). Increased levels of enzymatic activity of BACE1 was found in cerebrospinal fluid from patients having both mild cognitive impairment (MCI) and AD, thereby suggesting the importance of BACE1 enzymatic activity in conversion of MCI to AD.
BACE-1 Preparation Products And Raw materials
Raw materials
Preparation Products
BACE-1 Suppliers
Global( 27)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 15926423062 | 422450190@qq.com | China | 10132 | 58 |
| Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9965 | 58 |
| United States Biological | -- | sales@advtechind.com | United States | 6106 | 58 |
MEMAPSIN-2
HUMAN BETA-SECRETASE
HUMAN BACE-1
ASP-2
B-SECRETASE
BETA-SECRETASE ENZYME
BETA-SECRETASE HUMAN
BACE-1
Asp-2, BACE1, Memapsin-2
β-Secretase human
Anti-BACE, C-Terminal antibody produced in rabbit
β-secretase precursor
Anti-BACE1 (AB1) antibody produced in rabbit
Human BACE1/APS2 Protein, His Tag
Human BACE1/APS2 Protein, Fc Tag
158736-49-3