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4-Mercaptopyridine

CAS No.
4556-23-4
Chemical Name:
4-Mercaptopyridine
Synonyms
NOLA-009;NSC 76036;4-Thiopyridine;4-PYRIDINETHIOL;4-Pyridimethiol;Pyridine-4-thiol;Mercaptopyridine;4-Mecaptopyridine;4-mercatopyridine;4-Sulfanylpyridine
CBNumber:
CB2748207
Molecular Formula:
C5H5NS
Molecular Weight:
111.16
MDL Number:
MFCD00006422
MOL File:
4556-23-4.mol
MSDS File:
SDS
Last updated:2023-06-08 17:06:38

4-Mercaptopyridine Properties

Melting point 182-189 °C
Boiling point 194.0±13.0 °C(Predicted)
Density 1.161 (estimate)
refractive index 1.5605 (estimate)
storage temp. 2-8°C
solubility DMSO, Methanol
pka pK1:1.43(+1);pK2:8.86(0) (20°C)
form Crystalline Powder
color Yellow to yellow-green or brown
InChIKey FHTDDANQIMVWKZ-UHFFFAOYSA-N
CAS DataBase Reference 4556-23-4(CAS DataBase Reference)
EWG's Food Scores 1
NIST Chemistry Reference 4-Pyridinethiol(4556-23-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39-24/25
WGK Germany  3
RTECS  UT8578000
HS Code  29333990
NFPA 704
0
2 0

4-Mercaptopyridine price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 148202 4-Mercaptopyridine 95% 4556-23-4 1g $45.8 2024-03-01 Buy
Sigma-Aldrich 148202 4-Mercaptopyridine 95% 4556-23-4 10g $216 2024-03-01 Buy
TCI Chemical M0630 4-Mercaptopyridine >97.0%(T) 4556-23-4 5g $79 2024-03-01 Buy
TCI Chemical M0630 4-Mercaptopyridine >97.0%(T) 4556-23-4 25g $214 2024-03-01 Buy
TRC M225500 4-Mercaptopyridine 4556-23-4 1g $45 2021-12-16 Buy
Product number Packaging Price Buy
148202 1g $45.8 Buy
148202 10g $216 Buy
M0630 5g $79 Buy
M0630 25g $214 Buy
M225500 1g $45 Buy

4-Mercaptopyridine Chemical Properties,Uses,Production

Chemical Properties

4-Mercaptopyridine is Yellow to light yellow crystalline powder

Uses

4-Mercaptopyridine is a pyridine derivative used as a redox reagents for the in vitro refolding of a recombinantly expressed single-chain Fv fragment (scFvOx). Used in studies along with thiosulfate to measure alliinase activity.

Uses

mercaptopyridine is also known as sodium pyrithione. It is a preservative that is not commoly used.

Uses

4-Mercaptopyridine was used as a probe molecule to study the performance of the gold nanorod (AuNR)/polycaprolactone (PCL) fibrous mesh.

Purification Methods

Purify the thiol by dissolving ~45g in boiling H2O (100mL) (charcoal), filter and precipitate it by adding 50% aqueous NaOH (~80mL) to pH ~6. Dissolve the precipitate in EtOH, evaporate it to dryness, then crystallise it from boiling EtOH (~100mL, charcoal) to give yellow flat hexagonal plates (m 186o). It sublimes readily in vacuo. [King & Ware J Chem Soc 873 1939.] The picrate forms yellow needles from H2O with m 222o(dec). The 4-methylmercaptopyridine derivative crystallises from pet ether (m 47o , also 44-45o was reported, with a pK2 0 of 5.97) and was prepared by treatment with MeI/NaOH. Its picrate has m 2 4 5o (from H2O, MeOH or EtOH). The N-methyl-4-pyridinethiol derivative has m 168.5-170o (from EtOH), a pK2 0 of 1.30 and is soluble in CHCl3. [Albert & Barlin J Chem Soc 2384 1959, Beilstein 21 II 35, 22 III/IV 373, 22/7 V 147.]

626-61-9
17356-08-0
4556-23-4
37968-97-1
Synthesis of 4-Mercaptopyridine from 4-chloropyridine and Carbamimidothioic acid

4-Mercaptopyridine Preparation Products And Raw materials

Global( 249)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
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career henan chemical co
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CONIER CHEM AND PHARMA LIMITED
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WinWin Chemical CO., Limited
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Wuhan Fortuna Chemical Co., Ltd
+86-27-59207850 +86-13986145403 info@fortunachem.com China 5985 58

View Lastest Price from 4-Mercaptopyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Mercaptopyridine pictures 2021-11-11 4-Mercaptopyridine
4556-23-4
US $0.00 / Kg/Drum 1KG 98%min 1000kgs WUHAN FORTUNA CHEMICAL CO., LTD
4-Mercaptopyridine pictures 2021-07-02 4-Mercaptopyridine
4556-23-4
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
4-pyridinethiol pictures 2021-03-17 4-pyridinethiol
4556-23-4
US $90.00 / g 10g 99.8% 10tons Hebei shuoxi biotechnology co. LTD
  • 4-Mercaptopyridine pictures
  • 4-Mercaptopyridine
    4556-23-4
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
  • 4-pyridinethiol pictures
  • 4-pyridinethiol
    4556-23-4
  • US $90.00 / g
  • 99.8%
  • Hebei shuoxi biotechnology co. LTD
4-PYRIDINETHIOL 4-PYRIDYL MERCAPTAN 4-MERCAPTOPYRIDINE Pyridine-4-thiol 4-Mercaptopyridine, 96% 10GR 4-Mercaptopyridine, 96% 1GR Pyridine-4-thiol, 4-Mercaptopyridine, 4-Sulphanylpyridine Mercaptopyridine 4-Sulfanylpyridine NSC 76036 4-Pyridinethiol 4-Pyridyl Mercaptan 4-Mecaptopyridine 4-Thiopyridine Pyridine, 4-mercapto- Mercaptopyridine,90% 4-Pyridimethiol 4-mercapto-pyridin 4-mercatopyridine 1H-Pyridine-4-thione 4-Mercaptopyridine,96% 4-Mercaptopyridine,4-Pyridinethiol 4-Mercaptopyridine, 97.0%(T) NOLA-009 4-Mercaptopyridine> 4556-23-4 C5H4NS Pyridines Heterocyclic Building Blocks Building Blocks C5 Building Blocks C5 Chemical Synthesis Heterocyclic Building Blocks Pyridines Pyridine Amines Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds bc0001