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Salmeterol xinafoate

Salmeterol xinafoate Structure
Salmeterol xinafoate structure
CAS No.
94749-08-3
Chemical Name:
Salmeterol xinafoate
Synonyms
1-Hydroxy-2-naphthoate;Serevent;Salmeterol hydroxynaphthoate;Salmeterol Xinafoate (1609603);Arial;SN 408;Siduomi;GR 3343G;GR-33343G;Salmetedur
CBNumber:
CB2751968
Molecular Formula:
C36H45NO7
Molecular Weight:
603.74
MDL Number:
MFCD00897708
MOL File:
94749-08-3.mol
MSDS File:
SDS
Last updated:2023-11-20 12:07:38
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Salmeterol xinafoate Properties

Melting point 137-138°C
storage temp. 2-8°C
solubility H2O: slightly soluble
form solid
color white
Merck 14,8337
InChIKey XTZNCVSCVHTPAI-UHFFFAOYSA-N
CAS DataBase Reference 94749-08-3(CAS DataBase Reference)
FDA UNII 6EW8Q962A5

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280-P271
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-36-26
WGK Germany  3
RTECS  QJ1970500
HS Code  2922504500
NFPA 704
0
3 0

Salmeterol xinafoate price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S5068 Salmeterol xinafoate ≥98% (HPLC), solid 94749-08-3 10mg $225 2024-03-01 Buy
Sigma-Aldrich 1609603 Salmeterol xinafoate United States Pharmacopeia (USP) Reference Standard 94749-08-3 150mg $1070 2024-03-01 Buy
TCI Chemical A3190 Salmeterol Xinafoate >98.0%(HPLC)(T) 94749-08-3 250mg $69 2024-03-01 Buy
TCI Chemical A3190 Salmeterol Xinafoate >98.0%(HPLC)(T) 94749-08-3 1g $188 2024-03-01 Buy
Cayman Chemical 16009 Salmeterol xinafoate ≥98% 94749-08-3 10mg $110 2024-03-01 Buy
Product number Packaging Price Buy
S5068 10mg $225 Buy
1609603 150mg $1070 Buy
A3190 250mg $69 Buy
A3190 1g $188 Buy
16009 10mg $110 Buy

Salmeterol xinafoate Chemical Properties,Uses,Production

Description

Salmeterol hydroxynaphthoate is a new long-acting β2-selective adrenoceptor agonist introduced as a bronchodilator for the treatment of reversible airway obstruction in asthma and chronic bronchitis. It has bronchodilatory activity as intense and four times longerlasting than equivalent doses of salbutamol. Salmeterol hydroxynaphthoate is reported to be the first bronchodilator with significant anti-inflammatory activity and hence could complement prophylactic corticosteroid therapy.

Description

Salmeterol is a long-acting β2-adrenergic receptor agonist (β2-AR; EC50s = 0.79, 63.1, and 9.4 nM for β2-, β1-, and β3-ARs, respectively). It inhibits electrically-stimulated contraction of isolated guinea pig trachea strips (EC50 = 2.51 nM) and histamine-induced bronchoconstriction in guinea pigs via aerosol administration of doses ranging from 0.12 to 12 mM. Salmeterol binds to an exosite domain of β2-adrenergic receptors, producing a slow onset of action and prolonged activation. Formulations containing salmeterol have been used in the treatment of asthma, including exercise-induced asthma, and chronic obstructive pulmonary disease.

Chemical Properties

White to Off-White Solid

Originator

Glaxo (United Kingdom)

Uses

Bronchodilator; Beta2-adrenoceptor agonist

Uses

Smooth wheezing anti-inflammatory

Uses

A β2-Adrenergic agonist. Structural analog of Albuterol (A514500).

Uses

A ?-Adrenergic agonist. Structural analog of albuterol

Application

Salmeterol xinafoate is a potent and selective β2-adrenoceptor agonist (EC50 = 5.3 nM) that displays bronchodilator actions. Unlike other β2- adrenoceptor agonists, Salmeterol binds to exo-site domain of β2-AR receptors, producing a slow onset of action and prolonged activation. Clinically used for the treatment of asthma and chronic obstructive pulmonary disease(COPD).

Definition

ChEBI: Salmeterol xinafoate is a naphthoic acid.

brand name

Serevent (GlaxoSmithKline).

Biochem/physiol Actions

β2-adrenoceptor agonist.

storage

Desiccate at RT

Salmeterol xinafoate Preparation Products And Raw materials

Raw materials

Preparation Products

Atracurium besylate

Salmeterol xinafoate Suppliers

Global( 423)Suppliers
Supplier Tel Email Country ProdList Advantage
Jewim Pharmaceutical (Shandong) Co., Ltd.
+86-15552509998 +86-15621883869 liutf@jewim.com.cn China 251 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8617865335152 Mandy@hangyubiotech.com China 11013 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15928 58
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1811 55
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1807 55
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
Shanghai Yingrui Biopharma Co., Ltd. 		+86-21-33585366 - 03@ sales03@shyrchem.com CHINA 738 60
Lianyungang happen teng technology co., LTD 		15950718863 wang666xt@163.com CHINA 295 58
Supplier Advantage
Jewim Pharmaceutical (Shandong) Co., Ltd.
58
Zibo Hangyu Biotechnology Development Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Time Chemicals CO., Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
Shanghai Yingrui Biopharma Co., Ltd. 		60
Lianyungang happen teng technology co., LTD 		58

View Lastest Price from Salmeterol xinafoate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Salmeterol xinafoate pictures 2024-01-02 Salmeterol xinafoate
94749-08-3
 US $55.00-550.00 / kg 10kg 0.99 20tons Zibo Hangyu Biotechnology Development Co., Ltd
Salmeterol xinafoate pictures 2023-11-27 Salmeterol xinafoate
94749-08-3
 US $0.00 / KG 1KG 99% 20 TONS Wuhan Senwayer Century Chemical Co.,Ltd
Salmeterol xinafoate pictures 2023-03-25 Salmeterol xinafoate
94749-08-3
 US $60.00 / kg 1kg 99% 20 tons Hebei Duling International Trade Co. LTD
  • Salmeterol xinafoate pictures
  • Salmeterol xinafoate
    94749-08-3
  • US $55.00-550.00 / kg
  • 0.99
  • Zibo Hangyu Biotechnology Development Co., Ltd

Salmeterol xinafoate Spectrum

Salmeterol xinafoate(94749-08-3)1HNMR

94749-08-3(Salmeterol xinafoate)Related Search:

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2-Naphthoic acid 4-Phenylphenol CHLOROPHOSPHONAZO III 1-Hydroxyethylidene-1,1-diphosphonic acid Hydroquinone
1-Hydroxy-2-naphthoic acid Benzoic acid, 3-acetyl-4-(phenylmethoxy)-, methyl ester Salbutamol Acetonide

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(+/-) 4-HYDROXY-A1-[[[6-(4-PHENYLBUTOXY)HEXYL]AMINO]M-ETHYL]-1,3-BENZENEDIMETHANOL XINAFOATE GR 33343X XINAFOATE Arial GR-33343G Salmetedur Salmeterol, 1-Hydroxy-2-naphthoate 1,3-Benzenedimethanol, 4-hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-, (+-)-, 1-hydroxy-2-naphthalenecarboxylate (salt) 1,3-Benzenedimethanol, 4-hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-, 1-hydroxy-2-naphthalenecarboxylate (salt) (9CI) 2-Naphthalenecarboxylic acid, 1-hydroxy-, compd. with (+-)-4-hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol (1:1) 2-Naphthalenecarboxylic acid, 1-hydroxy-, compd. with 4-hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol (1:1) (9CI) GR 3343G Serevent Diskus Siduomi SN 408 SALMETEROL XINAFOATE SALMETEROL XINAFONATE 4-(1-Hydroxy-2-((6-(4-phenylbutoxy)hexyl)amino)ethyl)-2-(hydroxymethyl)phenol 1-hydroxy-2-naph GR 33343X xinafoate, (±) 4-Hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]m-ethyl]-1,3-benzenedimethanol xinafoate 2-(Hydroxymethyl)-4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]phenol 1-hydroxy-2-naphthoate (±)-4-Hydroxy-alpha1-[[[6-(4-phenylbutoxy)hexy])amino]methyl]-1,3-benzenedimethanol xinafoate Salmeterol Xinafoate 2-(Hydroxymethyl)-4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]phenol 1-hydroxy-2-naphthoate Salmeterol Xinafoate (150 mg) SalMeterol Xinafoate Aerosol salMaterol xinafoate 4-Hydroxy-α1-[[[6-(4-phenylbutoxy)hexyl]aMino]Methyl]-1,3-benzenediMethanol 1-Hydroxy-2-naphthalenecarboxylic Acid SalMeterol-d12 Xinafoate salt 4-(1-Hydroxy-2-((6-(4-phenylbutoxy)hexyl)aMino)ethyl)-2-(hydroxyMethyl)phenol 1-hydroxy-2-naphthoate AtracuriuM Besilate IMp. J (EP) 4-(1-Hydroxy-2-((6-(4-phenylbutoxy)hexyl)amino)ethyl)-2-(hydroxymethyl)phenol 1-hydroxy-2-naphtho SalMeterol Solution 4-Hydroxy-alpha-({[6-(4-phenylbutoxy)hexyl]amino}methyl)-1,3-benzenedimethanol xinafoate, GR 33343X xinafoate SalMeterol Hydroxynapthoate JigMei acid salMeterol 4-hydroxy-α1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol with 1-hydroxy-2-naphthalenecarboxylic acid(1:1) Salmaterol Xinafloate 4-(1-hydroxy-2-((6-(4-phenylbutoxy)hexyl)amino)ethyl)-2-(hydroxymethyl)phenol 8-hydroxy-1-naphthoate 4-Hydroxy-α1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol 1-hydroxy-2-naphthalenecarboxylic acid salt Salmeterol xinafoate CRS Salmeterol xinafoate for system suitability CRS Salmeterol xinafoate for peak identification CRS Salmeterol in Methanol Salmeterol xinafoate USP/EP/BP Salmeterol Xinafoate (GR 33343X xinafoate) Salmeterol Xinafoate-d3 Salmeterol XinafoateQ: What is Salmeterol Xinafoate Q: What is the CAS Number of Salmeterol Xinafoate Q: What is the storage condition of Salmeterol Xinafoate Q: What are the applications of Salmeterol Xinafoate Salmeterol D12 Xinafoate saltQ: What is Salmeterol D12 Xinafoate salt Q: What is the CAS Number of Salmeterol D12 Xinafoate salt Q: What is the storage condition of Salmeterol D12 Xinafoate salt Q: What are the applications of Salmeterol D12 Xinafoate salt Salmeterol Xinafoate (1609603) Salmeterol hydroxynaphthoate 1-Hydroxy-2-naphthoate Serevent Salmeterol sinaphthate 94749-08-3 29213-08-3 C36H45NO7 C25H37NO4C11H8O3 C25H37NO4xC11H8O3 C36H33D12NO7 Intermediates & Fine Chemicals