Propacetamol
- CAS No.
- 66532-85-2
- Chemical Name:
- Propacetamol
- Synonyms
- Propacetamo;Pro-Dafalgan;PROPACETAMOL;Propacatemol;Propacetamol USP/EP/BP;4-Acetamidophenyl N,N-diethylglycinate;4-acetamidophenyl N,N-diethylaminoacetate;N，N-Diethylglycine 4-(acetylamino)phenyl ester;(Diethylamino)acetic acid 4-(acetylamino)phenyl;Glycine, N,N-diethyl-, 4-(acetylamino)phenyl ester
- CBNumber:
- CB2759429
- Molecular Formula:
- C14H20N2O3
- Molecular Weight:
- 264.32
- MDL Number:
- MFCD00864309
- MOL File:
- 66532-85-2.mol
- MSDS File:
- SDS
| Melting point | 55-57 °C |
|---|---|
| Boiling point | 434.5±30.0 °C(Predicted) |
| Density | 1.132±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | H2O : 100 mg/mL (378.33 mM; Need ultrasonic) |
| pka | 14.20±0.70(Predicted) |
| CAS DataBase Reference | 66532-85-2(CAS DataBase Reference) |
| FDA UNII | 5CHW4JMR82 |
| NCI Drug Dictionary | propacetamol |
| ATC code | N02BE05 |
Propacetamol price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0015798 | N,N-DIETHYLGLYCINE-4-(ACETYLAMINO)PHENYL ESTER 95.00% | 66532-85-2 | 1G | $939.89 | 2021-12-16 | Buy |
| AvaChem | 3086B | Propacetamol | 66532-85-2 | 100mg | $35 | 2021-12-16 | Buy |
| AvaChem | 3086B | Propacetamol | 66532-85-2 | 1g | $95 | 2021-12-16 | Buy |
| AvaChem | 3086B | Propacetamol | 66532-85-2 | 10g | $475 | 2021-12-16 | Buy |
| AHH | MT-58176 | Propacetamol 98% | 66532-85-2 | 5g | $910 | 2021-12-16 | Buy |
Propacetamol Chemical Properties,Uses,Production
Description
Propacetamol is the prodrug of paracetamol (acetaminophen), used for intravenous administration. It results from eombination of paracetamol and diethylglycine. Causes contact dermatitis and airborne dermatitis in nurses. Allergenic properties are due to the N,N' -diethylglycine moiety, and not to the paracetamol moiety.
Uses
Propacetamol hydrochloride is a water-soluble prodrug for intravenous administration resulting in the liberation of paracetamol.
Definition
ChEBI: Propacetamol is an alpha-amino acid ester.
Contact allergens
Propacetamol is a prodrug of paracetamol (acetaminophen) used for intravenous administration. It results from the combination of paracetamol and diethylglycine. It caused contact (hand and airborne) dermatitis in nurses and acute systemic dermatitis (pompholyx and nummular dermatitis, generalized eczema, urticaria-like eruption) in nurses who had became sick and received intravenous propacetamol. Allergenic properties are due to the N,N-diethylglycine moiety, and not to the paracetamol moiety. Propacetamol is now substituted by a solution of paracetamol in mannitol (Perfalgan?).
Mechanism of action
It is a soluble glycine prodrug derivative of paracetamol. It is used as hydrochloride, for intramuscular or intravenous application and is rapidly metabolized to free paracetamol .
Propacetamol Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| HubeiwidelychemicaltechnologyCo.,Ltd | 18627774460 | faith@widelychemical.com | CHINA | 742 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569265 +86-18612256290 | 1056@dideu.com | China | 3632 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29271 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
| Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 | daisy@crovellbio.com | China | 5964 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| Hebei Duling International Trade Co. LTD | +8618032673083 | sales05@hbduling.cn | China | 15745 | 58 |
View Lastest Price from Propacetamol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-03-06 | Propacetamol
66532-85-2
|
US $9.00 / KG | 1KG | 99.8% | 100tons | Hebei Guanlang Biotechnology Co,.LTD | |
 |
2021-07-20 | Propacetamol
66532-85-2
|
US $1.00-1.00 / KG | 1g | 99% | 50tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2021-06-10 | Propacetamol USP/EP/BP
66532-85-2
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited |
-
- Propacetamol
66532-85-2
- US $9.00 / KG
- 99.8%
- Hebei Guanlang Biotechnology Co,.LTD
-
- Propacetamol
66532-85-2
- US $1.00-1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- Propacetamol USP/EP/BP
66532-85-2
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited