ChemicalBook >> CAS DataBase List >>alpha-Angelica lactone
alpha-Angelica lactone
- CAS No.
- 591-12-8
- Chemical Name:
- alpha-Angelica lactone
- Synonyms
- 2(3H)-Furanone, 5-methyl-;5-METHYL-2(3H)-FURANONE;α-Angelica lactone;5-Methylfuran-2(3H)-one;ANGELICALACTONE;3-PENTEN-4-OLIDE;4-HYDROXY-3-PENTENOIC ACID GAMMA-LACTONE;FEMA 3293;A-ANGELICALACTONE;A-ANGELIC LACTONE
- CBNumber:
- CB2760151
- Molecular Formula:
- C5H6O2
- Molecular Weight:
- 98.1
- MDL Number:
- MFCD00005375
- MOL File:
- 591-12-8.mol
- MSDS File:
- SDS
Last updated:2023-08-21 17:50:07
| Melting point | 13-17 °C(lit.) |
|---|---|
| Boiling point | 55-56 °C12 mm Hg(lit.) |
| Density | 1.092 g/mL at 25 °C(lit.) |
| FEMA | 3293 | 4-HYDROXY-3-PENTENOIC ACID LACTONE |
| refractive index |
n |
| Flash point | 155 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform, Ethyl Acetate |
| form | Oil |
| pka | pK1:4.3 (25°C) |
| Specific Gravity | 1.101.092 |
| color | Clear Light Yellow |
| Odor | at 10.00 % in dipropylene glycol. sweet solvent nutty tonka coumarin tobacco |
| Odor Type | coconut |
| Water Solubility | 5 g/100 mL (25 ºC) |
| Merck | 14,647 |
| JECFA Number | 221 |
| BRN | 108394 |
| LogP | 0.84 |
| CAS DataBase Reference | 591-12-8(CAS DataBase Reference) |
| Substances Added to Food (formerly EAFUS) | 4-HYDROXY-3-PENTENOIC ACID LACTONE |
| FDA UNII | 29CRF6L9C5 |
| NIST Chemistry Reference | 2(3H)-Furanone, 5-methyl-(591-12-8) |
| EPA Substance Registry System | 5-Methyl-2(3H)-furanone (591-12-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H303-H227 | |||||||||
| Precautionary statements | P210-P280-P403+P235-P501-P210e-P280a-P370+P378a-P501a | |||||||||
| Safety Statements | 24/25 | |||||||||
| RIDADR | NA 1993 / PGIII | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | LU5075000 | |||||||||
| F | 10-21 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29322090 | |||||||||
| Toxicity | LD50 orl-mus: 2800 mg/kg DCTODJ 3,249,80 | |||||||||
| NFPA 704 |
|
alpha-Angelica lactone price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W329304 | α-Angelica lactone 98%, FG | 591-12-8 | 100g | $181 | 2024-03-01 | Buy |
| Sigma-Aldrich | W329304 | α-Angelica lactone 98%, FG | 591-12-8 | 250g | $340 | 2024-03-01 | Buy |
| Sigma-Aldrich | W329304 | α-Angelica lactone 98%, FG | 591-12-8 | 1kg | $847 | 2024-03-01 | Buy |
| Sigma-Aldrich | A86406 | α-Angelica lactone 98% | 591-12-8 | 10g | $125 | 2024-03-01 | Buy |
| TCI Chemical | A1090 | alpha-Angelicalactone >98.0%(GC) | 591-12-8 | 25g | $58 | 2024-03-01 | Buy |
alpha-Angelica lactone Chemical Properties,Uses,Production
Chemical Properties
α-Angelica lactone has a sweet, herbaceous odor reminiscent of tobacco.
Chemical Properties
clear colorless to straw yellow liquid
Occurrence
Reported found in grape, white bread, soy bean and licorice.
Uses
alpha-Angelicalactone acts as acancer chemopreventive agent. It is used in the synthesis of glutathione and the activity of glutathione-S-transferase and UDP-glucunonosyltransferase detoxification enzymes in esophagus, stomach, intestine, and liver. It is used in oral care formulations to round out mint notes and in coffee flavors.
Preparation
By dry distillation of levulinic acid
Definition
ChEBI: Alpha-angelica lactone is an angelica lactone and a butenolide. It is functionally related to a but-3-en-4-olide. It is a tautomer of a beta-angelica lactone.
Taste threshold values
Taste characteristics at 100 ppm: sweet, creamy, coconut, vanilla hay and coumarin-like nuances
General Description
α-Angelica lactone, a cyclic lactone that occurs naturally in tobacco, is generally used in tobacco flavoring.
Biochem/physiol Actions
Plant-derived cancer chemopreventive agent. Increases the synthesis of glutathione and the activity of glutathione-S-transferase and UDP-glucunonosyltransferase detoxification enzymes in esophagus, stomach, intestine, and liver.
Safety Profile
Moderately toxic by ingestion andintraperitoneal routes. When heated to decomposition itemits acrid smoke and irritating fumes.
alpha-Angelica lactone Preparation Products And Raw materials
Global( 270)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8823 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 18192627656 | 1012@dideu.com | China | 3422 | 58 |
View Lastest Price from alpha-Angelica lactone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-08-21 | alpha-Angelica lactone
591-12-8
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-03-06 | alpha-Angelica lactone
591-12-8
|
US $5.00-2.00 / KG | 1KG | 99% | 10000kg | Hebei Guanlang Biotechnology Co,.LTD | |
 |
2023-02-08 | alpha-Angelica lactone
591-12-8
|
US $25.00 / kg | 1kg | 99% | 5000 Ton | Hebei Duling International Trade Co. LTD |
-
- alpha-Angelica lactone
591-12-8
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- alpha-Angelica lactone
591-12-8
- US $5.00-2.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co,.LTD
-
- alpha-Angelica lactone
591-12-8
- US $25.00 / kg
- 99%
- Hebei Duling International Trade Co. LTD
591-12-8(alpha-Angelica lactone)Related Search:
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α-Angelicalactone >
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3-PENTEN-4-OLIDE
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α-Angelica lactone
591-12-8
0591-12-08
Carbonyl Compounds
Building Blocks