ChemicalBook >> CAS DataBase List >>Rink Amide Linker

Rink Amide Linker

Rink Amide Linker structure

CAS No.: 145069-56-3

Chemical Name:: Rink Amide Linker

Synonyms: FMoc-Linker;RINK AMIDE LINKER;FMOC-RINK LINKER;DK7874;RAMAGE;Fmoc-Liner;KNORR LINKER;Rink Amide Linke;Rink AMind Linker;FMOC-AMIDE-LINKER

CBNumber:: CB3104341

Molecular Formula:: C32H29NO7

Molecular Weight:: 539.58

MDL Number:: MFCD00153509

MOL File:: 145069-56-3.mol

MSDS File:: SDS

Last updated:2023-11-16 17:07:08

Request For Quotation

Rink Amide Linker Properties

Melting point	~180 °C (dec.)
storage temp.	2-8°C
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	Powder
BRN	5841553
InChIKey	UPMGJEMWPQOACJ-UHFFFAOYSA-N
SMILES	C(O)(=O)COC1=CC=C(C(C2=CC=C(OC)C=C2OC)NC(OCC2C3C(=CC=CC=3)C3C2=CC=CC=3)=O)C=C1
CAS DataBase Reference	145069-56-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Hazard Codes	Xi
Risk Statements	36/38
Safety Statements	22-24/25-37/39-26
WGK Germany	3
HS Code	29242995

Rink Amide Linker price More Price(7)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	38784	4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid ≥99.0% (HPLC)	145069-56-3	5g	$50.8	2023-01-07	Buy
TRC	R590710	RinkAmideLinker	145069-56-3	2.5g	$75	2021-12-16	Buy
AK Scientific	CS-W011472	2-(4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)(2,4-dimethoxyphenyl)methyl)phenoxy)aceticacid	145069-56-3	25g	$108	2021-12-16	Buy
American Custom Chemicals Corporation	LIN0000011	RINK AMIDE LINKER 95.00%	145069-56-3	1G	$115.5	2021-12-16	Buy
ApexBio Technology	A7042	RinkAmideLinker	145069-56-3	25g	$148	2021-12-16	Buy

Product number	Packaging	Price	Buy
38784	5g	$50.8	Buy
R590710	2.5g	$75	Buy
CS-W011472	25g	$108	Buy
LIN0000011	1G	$115.5	Buy
A7042	25g	$148	Buy

Rink Amide Linker Chemical Properties,Uses,Production

Uses

Rink amide linker (CAS# 145069-56-3) is a selective aldose reductase inhibitor and a potential antidiabetic drug.

Application

Most linkers are bifunctional spacers, with one end permanently anchoring to the resin and the other end temporarily linking to the peptide. Peptides anchoring to Rink linker can be easily cleaved under acidic conditions. Since the discovery of Rink linker, it has been grafted to a variety of resins and widely used for scientific investigations and industrial solid-phase peptide synthesis. Thus, Rink Amide Linker is the key reagent to prepare this series of Rink-resins[1].

Origin

Rink Amide Linker was first designed by Rink and further developed by Bernatowicz and co-workers for the preparation of peptide C-terminal amides[1]. Rink Amide Linker is also known as commercial Knorr linker.

References

[1] Qin L, et al. An improved and practical synthesis of Fmoc Rink linker. Journal of Chemical Research, 2019.

Rink Amide Linker Preparation Products And Raw materials

Raw materials

Preparation Products

Rink Amide Linker Suppliers

Global( 240)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Chemtour Biotech Co., Ltd	+8617327281506	market@chemtour.com	China	1472	58
SIMAGCHEM CORP	+86-13806087780	sale@simagchem.com	China	17367	58
Sichuan HongRi Pharma-Tech Co.,Ltd	+86-028-64841719 +8618980456393	daisy@enlaibio.com	China	1369	58
Hebei Dangtong Import and export Co LTD	+8615632927689	admin@hbdangtong.com	China	991	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15371	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	+86 18953170293	sales@sdzschem.com	China	2931	58

Supplier	Advantage
Chemtour Biotech Co., Ltd	58
SIMAGCHEM CORP	58
Sichuan HongRi Pharma-Tech Co.,Ltd	58
Hebei Dangtong Import and export Co LTD	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	58

4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid: Synthesis, bioactivity and toxicity
The 4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid is a chemical linker, which is often used to synthesize pept....
Mar 15，2023

View Lastest Price from Rink Amide Linker manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-23	Fmoc -Rink Linker 145069-56-3	US $0.00-0.00 / kg	1kg	98%	1T+	Sichuan HongRi Pharma-Tech Co.,Ltd
2024-04-23	Rink Amide Linker 145069-56-3	US $100.00-80.00 / kg	1kg	99%	200Tons	Hebei Dangtong Import and export Co LTD
2021-07-13	4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid 145069-56-3	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

Fmoc -Rink Linker
145069-56-3
US $0.00-0.00 / kg
98%
Sichuan HongRi Pharma-Tech Co.,Ltd

Rink Amide Linker
145069-56-3
US $100.00-80.00 / kg
99%
Hebei Dangtong Import and export Co LTD

4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid
145069-56-3
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

145069-56-3(Rink Amide Linker)Related Search:

Fmoc-Phe-OH Fmoc-Asp(OtBu)-OH Fmoc-Lys(Boc)-OH Dimethyldimethoxysilane Fomesafen

RINK AMIDE RESIN 4-Dimethylaminopyridine N-(9-Fluorenylmethoxycarbonyloxy)succinimide 4-Dimethylaminobenzaldehyde Dimethoxymethane

Phenyltriethoxysilane Glycine 9-Fluorenylmethyl chloroformate 6-Aminocaproic acid 3,4'-DIAMINODIPHENYLMETHANE

L-Fmoc-Aspartic acid alpha-tert-butyl ester 2-Dimethylaminoethanol FMOC-RINK AMIDE-LINKER

1of4

Rink AMid Linker, (FoMc-AM, Knorr linker) Rink AMind Linker FMOC-2,4-DIMETHOXY-4'-(CARBOXYMETHYLOXY)-BENZHYDRYLAMINE 4-[(2,4-DiMethoxyphenyl)(FMoc-aMino)Methyl]phenoxyacetic acid, 98+% RINK AMIDE REAGENT N-FMOC-(2,4-DIMETHOXYPHENYL)AMINOMETHYL PHENOXY ACETIC ACID P-[(R,S)-A-[1-(9H-FLUOREN-9-YL)-METHOXYFORMAMIDO]-2,4-DIMETHOXYBENZYL]-PHENOXYACETIC ACID P-((R,S)-ALPHA-[1-(9H-FLUOREN-9-YL)-METHOXYFORMAMIDO]-2,4-DIMETHOXYBENZYL)-PHENOXYACETIC ACID P-((R,S)-ALPHA-[1-(9H-FLOUREN-9-YL)-METHOXYFORMAMIDO]-2,4-DIMETHOXYBENZYL)-PHENOXYACETIC ACID N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-2,4-DIMETHOXY-4'-(CARBOXYMETHYLOXY)-BENZHYDRYLAMINE 4-(R,S)-A-[1-(9H-FLUOREN-9-YL)-METHOXY-FORMAMIDO]-2,4-DIMETHOXYBENZYL-PHENOXYACETIC-ACID 4'-[(R,S)-ALPHA-[1-(9-FLUORENYL)METHOXYCARBONYLAMINO]-2,4-DIMETHOXYBENZYL]-PHENOXYACETIC ACID 4'-[(R,S)-ALPHA-[1-(9-FLUORENYL)METHOXYCARBONYLAMINO]-2,4-DIMETHOXYBENZYL]-PHENOL 4-[(R,S)-ALPHA-1-(9H-FLUREN-9-YL)-METHOXY FORMAMIDO]-2,4-DIMETHOXYBENZYLPHENOXYACETIC ACID 4-[(R,S)-ALPHA-[1-(9H-FLUOREN-9-YL)-METHOXY-FORMAMIDO]-2,4-DIMETHOXYBENZYL-PHENOXYACETIC ACID 4-(2',4'-DIMETHOXYPHENYL)-FMOC-AMINOMETHYL-PHENOXYACETIC ACID 4-[(2,4-DIMETHOXYPHENYL)(FMOC-AMINO)METHYL]PHENOXYACETIC ACID FMOC-AMIDE-LINKER FMOC-RINK AMIDE-LINKER FMOC RINK ACETIC ACID LINKER FMOC-NH-SAL RESIN LINKER KNORR LINKER Rink Amide Linker (4-((2,4-Dimethoxyphenyl)(Fmoc Amino)Methyl)Phenoxyacetic Acid 145069-56-3 C32h29no7 Rink Amide Linker (4-((2,4-Dimethoxyphenyl)(Fmoc Amino)Methyl)Phenoxyacetic Acid Fmoc-Liner Fmoc-Linker(4-[(2,4-Dimethoxyphenyl)(Fmoc-Amino)Methyl]-PhenoxyaceticAcid) 4-[(2,4-dimethoxyphenyl)(fmoc-amino)me] phenoxy acetic acid 4-[(2,4-DIMETHOXYPHENYL)(FMOC-AMINO)METHYL]PHENOXYACETIC ACID[RINK AMIDE LINKER] 4-[(2,4-DIMETHOXYPHENYL) (FMOC-AMINO) METHYL] PHENOXYACETIC ACID RINK AMIDE LINKER 98.5% RINK AMIDE LINKER:KNORR LINKER:4-[(R,S)-A-[1-(9H-FLUOREN-9-YL)-METHOXY-FORMAMIDO]-2,4-DIMETHOXYBENZYL-PHENOXYACETIC ACID Knorr-Linker, 4-{(R,S)-alpha-[1-(9-Fluorenyl)methoxycarbonylamino]-2,4-dimethoxybenzyl}-phenoxyacetic acid RINK AMIDE LINKER, 98.5% MIN. 4-[(R,S)--[1-(9H-Fluoren-9-yl)-methoxyformamido]-2,4-dimethoxybenzylphenoxyacetic acid 4-[(R,S)-a-[1-(9H-Fluoren-9-yl)-methoxy-formamido]-2 2-(4-((((9H-fluoren-9-yl)methoxy)carbonylamino)(2,4-dimethoxyphenyl)methyl)phenoxy)acetic acid 4-[(R,S)-a-[1-(9H-Fluoren-9-yl)-methoxy-formamido] 2-{4-[(2,4-diMethoxyphenyl)({[(9H-fluoren-9-ylMethoxy)carbonyl]aMino})Methyl]phenoxy}acetic acid Fmoc-Knorr-Linker: Fmoc-Rink Amide Linker (2), 4′-{(R,S)-alpha-[1-(9-Fluorenyl)methoxycarbonylamino]-2,4-dimethoxybenzyl}-phenoxyacetic acid Rink Amide Linker (4-((2,4-Dimethoxyphenyl)(FMOC amino)methyl)ph Rink Amide Linke 2-[4-[(2,4-dimethoxyphenyl)-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]methyl]phenoxy]acetic acid Rink Amide Linker, 99% min. 4-[(2,4-Dimethoxyphenyl)(Fmoc-Amino)Methyl]PhenoxyaceticAci 4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid USP/EP/BP DK7874 Rink Amide Linker Resin (Knorr Linker) extrapure, 99% RINK AMIDE LINKER FMOC-RINK LINKER FMoc-Linker RAMAGE 145069-56-3 145068-56-3 C32H28NO7 C32H29NO7 Bifunctional Crosslinkers Linkers Peptide Synthesis Specialty Synthesis