Methylthiouracil
- CAS No.
- 56-04-2
- Chemical Name:
- Methylthiouracil
- Synonyms
- MZU;Mtu;Thyril;Alkiron;Basecil;Muracil;Muracin;Orcanon;Thioryl;Thiuryl
- CBNumber:
- CB3108758
- Molecular Formula:
- C5H6N2OS
- Molecular Weight:
- 142.18
- MDL Number:
- MFCD00006040
- MOL File:
- 56-04-2.mol
| Melting point | ~330 °C (dec.)(lit.) |
|---|---|
| Density | 1.291 (estimate) |
| refractive index | 1.6430 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Heated), Methanol (Slightly, Heated) |
| form | Liquid |
| pka | pKa 8.2 (Uncertain) |
| color | Clear colorless to yellow |
| Water Solubility | INSOLUBLE |
| Merck | 14,6128 |
| BRN | 115648 |
| Stability | Incompatible with strong oxidizing agents, iodine, metals. |
| InChIKey | HWGBHCRJGXAGEU-UHFFFAOYSA-N |
| CAS DataBase Reference | 56-04-2(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | QW24888U5F |
| ATC code | H03BA01 |
| Proposition 65 List | Methylthiouracil |
| NIST Chemistry Reference | 6-Methyl-2-thiouracil(56-04-2) |
| IARC | 2B (Vol. Sup 7, 79) 2001 |
| EPA Substance Registry System | Methylthiouracil (56-04-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H317 | |||||||||
| Precautionary statements | P261-P272-P280-P302+P352-P333+P313-P362+P364 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-40 | |||||||||
| Safety Statements | 36/37-45 | |||||||||
| RIDADR | UN 3077 9 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | YR0875000 | |||||||||
| Hazard Note | Irritant/Possible Carcinogen | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29335995 | |||||||||
| Toxicity | MLD in rabbits (mg/kg): 2486 orally (Simon) | |||||||||
| NFPA 704 |
|
Methylthiouracil price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 69400 | 6-Methyl-2-thiouracil purum, ≥98.0% S basis (elemental analysis) | 56-04-2 | 100g | $113 | 2024-03-01 | Buy |
| Sigma-Aldrich | 69400 | 6-Methyl-2-thiouracil purum, ≥98.0% S basis (elemental analysis) | 56-04-2 | 500g | $202 | 2023-06-20 | Buy |
| TCI Chemical | M0443 | 6-Methyl-2-thiouracil >98.0%(T) | 56-04-2 | 25g | $22 | 2024-03-01 | Buy |
| TCI Chemical | M0443 | 6-Methyl-2-thiouracil >98.0%(T) | 56-04-2 | 500g | $264 | 2024-03-01 | Buy |
| Alfa Aesar | A17982 | 6-Methyl-2-thiouracil, 98% | 56-04-2 | 50g | $23.1 | 2023-06-20 | Buy |
Methylthiouracil Chemical Properties,Uses,Production
Chemical Properties
white powder
Uses
antithyroid agent
Uses
6-?Methyl-?2-?thiouracil is a derivative of methylthiouracil (M330710), a competitive inhibitor of Nitric Oxide Synthase (NOS). Potential anti-inflammatory agent.
Definition
ChEBI: Methylthiouracil is a pyrimidone.
General Description
White crystalline powder with an odor of onions and a bitter taste. A saturated aqueous solution is neutral or slightly acidic.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Methylthiouracil reacts with strong oxidizing agents. Forms complexes with metals and is oxidized by iodine and other sulfhydryl oxidizing agents .
Fire Hazard
Flash point data for Methylthiouracil are not available. Methylthiouracil is probably combustible.
Safety Profile
Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by intraperitoneal route. Moderately toxic by ingestion. Human teratogenic and reproductive effects by an unspecified route: developmental abnormalities of the endocrine system and effects on newborn including neonatal measures or effects. Experimental reproductive effects. Used to treat hyperthyroidism. When heated to decomposition it emits very toxic fumes of NOx and SOx.
Purification Methods
Crystallise the thiouracil from a large volume of H2O. Purify it further by dissolving in base, adding charcoal, filtering and acidifying with AcOH. Suspend the wet solid (ca 100g) in boiling H2O (1L), stir and add AcOH (20mL), stir and refrigerate. Collect the product, wash it with cold H2O (4 x 200mL), drain it for several hours then place it in an oven at 70o to constant weight. [IR: Short & Thompson J Chem Soc 168 1952, Foster & Snyder Org Synth Coll Vol IV 638 1063, Beilstein 24 III/IV 1289.]
Methylthiouracil Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 +86-13986145403 | info@fortunachem.com | China | 5988 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 | kaia@neputrading.com | China | 1011 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8823 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Shanghai Longyu Biotechnology Co., Ltd. | +8615821988213 | info@longyupharma.com | China | 2531 | 58 |
View Lastest Price from Methylthiouracil manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-08-18 | Methylthiouracil
56-04-2
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2022-09-29 | METHYLTHIOURACIL
56-04-2
|
US $2.00 / kg | 1kg | 99% | 10000kg | Wuhan ShuEr Biology Technology Co.,Ltd | |
 |
2022-02-25 | Methylthiouracil
56-04-2
|
US $10.00 / KG | 1KG | 99% | 500tons/month | Shanxi Naipu Import and Export Co.,Ltd |
-
- Methylthiouracil
56-04-2
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- METHYLTHIOURACIL
56-04-2
- US $2.00 / kg
- 99%
- Wuhan ShuEr Biology Technology Co.,Ltd
-
- Methylthiouracil
56-04-2
- US $10.00 / KG
- 99%
- Shanxi Naipu Import and Export Co.,Ltd
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