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4-Chloro-4'-fluorobutyrophenone

4-Chloro-4'-fluorobutyrophenone Structure
4-Chloro-4'-fluorobutyrophenone structure
CAS No.
3874-54-2
Chemical Name:
4-Chloro-4'-fluorobutyrophenone
Synonyms
4-CHLORO-4-FLUOROBUTYROPHENONE;NSC 87082;LUMAT-009;JACS-3874-54-2;AKOS BBS-00006481;uorobutyrophenone;TIMTEC-BB SBB003536;4-Chloro-4'-fluorobu;Haloperidol Impurity 1;4-chloro-4 '-flubutanone
CBNumber:
CB3118281
Molecular Formula:
C10H10ClFO
Molecular Weight:
200.64
MDL Number:
MFCD00001007
MOL File:
3874-54-2.mol
MSDS File:
SDS
Last updated:2024-03-26 14:13:49
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4-Chloro-4'-fluorobutyrophenone Properties

Melting point 5-6 °C
Boiling point 130-132 °C (0.97513 mmHg)
Density 1.22 g/mL at 25 °C(lit.)
refractive index n20/D 1.5255(lit.)
Flash point >230 °F
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)
form Oil
color Slightly yellow-greenish clear
PH 4.05 at 23.1℃ and 10g/L
Water Solubility 0.38 g/L (20 ºC)
BRN 608741
InChIKey HXAOUYGZEOZTJO-UHFFFAOYSA-N
LogP 2.84 at 30℃
CAS DataBase Reference 3874-54-2(CAS DataBase Reference)
FDA UNII FVL03C7JRR
NIST Chemistry Reference 1-Butanone, 4-chloro-1-(4-fluorophenyl)-(3874-54-2)
EPA Substance Registry System 1-Butanone, 4-chloro-1-(4-fluorophenyl)- (3874-54-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312a-P330-P501a
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38-20/21/22
Safety Statements  24/25-36-26
WGK Germany  3
Hazard Note  Irritant
TSCA  Yes
HS Code  2914790090
NFPA 704
1
2 0

4-Chloro-4'-fluorobutyrophenone price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C43609 4-Chloro-4′-fluorobutyrophenone 97% 3874-54-2 25g $54.3 2024-03-01 Buy
Sigma-Aldrich C43609 4-Chloro-4′-fluorobutyrophenone 97% 3874-54-2 100g $138 2023-06-20 Buy
TCI Chemical C1294 4-Chloro-4'-fluorobutyrophenone >97.0%(GC) 3874-54-2 25g $44 2024-03-01 Buy
Alfa Aesar A11121 4-Chloro-4'-fluorobutyrophenone, 96% 3874-54-2 25g $22.9 2021-12-16 Buy
Alfa Aesar A11121 4-Chloro-4'-fluorobutyrophenone, 96% 3874-54-2 100g $59 2021-12-16 Buy
Product number Packaging Price Buy
C43609 25g $54.3 Buy
C43609 100g $138 Buy
C1294 25g $44 Buy
A11121 25g $22.9 Buy
A11121 100g $59 Buy

4-Chloro-4'-fluorobutyrophenone Chemical Properties,Uses,Production

Chemical Properties

slightly yellow-greenish clear oil

Uses

4-Chloro-4''-fluorobutyrophenone (cas# 3874-54-2) is a compound useful in organic synthesis.

Synthesis

The purified alkyne (5 mmol) was treated with a solution of HNTf2 (60-200 mol %) in 1,4-dioxane in apreheated oil bath at 100°C, under magnetic stirring, for 18-52 h, and the corresponding ketone was purified by column chromatography after cooling 4-Chloro-4'-fluorobutyrophenone. The reaction crude was purified by column chromatography using 20% AcOEt in n-hexane as an eluent. Isolated yield: 850 mg (85%). R f (20% AcOEt in n-hexane): 0.66. GC-MS (m/ z, M+? 200), major peaks found: 200 (1%), 164 (1%), 138 (43%), 123 (100%), 107 (10%). 1H NMR (δ, ppm; J, Hz): 8.03-7.97 (2C-H arom, mult), 7.17-7.09 (2C-H arom, mult), 3.68 (CH2, t, J = 6.2), 3.15 (CH2, t, J = 7.0), 2.22 (CH2, tt, J = 7.0, 6.2). 13C NMR (δ, ppm; J, Hz): 197.3 (C=O), 166.1 (C, d, J 1 C-F = 254.7), 133.2 (C, d, J 4 C-F = 4.3), 130.6 (2CH, d, J 3 C-F = 9.3), 115.9 (2CH, d, J 2 C-F = 22.2), 44.6 (CH2), 35.2 (CH2), 26.7 (CH2).
4-Chloro-4'-fluorobutyrophenone synthesis

4-Chloro-4'-fluorobutyrophenone synthesis

462-06-6
4635-59-0
3874-54-2
Synthesis of 4-Chloro-4'-fluorobutyrophenone from Fluorobenzene and 4-Chlorobutyryl chloride

4-Chloro-4'-fluorobutyrophenone Preparation Products And Raw materials

Raw materials

Preparation Products

ITI-722 Cyclopropyl 4-fluorophenyl ketone Ciproxifan

4-Chloro-4'-fluorobutyrophenone Suppliers

Global( 390)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hengmao New Materials Technology CO., LIMITED
+86-0086-1773693-3208 +8617736933208 1137059254@qq.com China 9287 58
ZHEJIANG JIUZHOU CHEM CO., LTD
+86-0576225566889 +86-13454675544 admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com China 20000 58
Dorne Chemical Technology co. LTD 		+86-13583358881 +86-18560316533 Ethan@dornechem.com China 292 58
Shandong Hanjiang Chemical Co., Ltd 		+86-0533-2066820 +8618369939125 hanson@sdhanjiang.com China 1527 58
Wuhan Xinhao Biotechnology Co., Ltd 		+86-18120578002 +86-18120578002 xinhao-6@xinhaoshengwu.com China 350 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15371 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
Nanjing ChemLin Chemical Industry Co., Ltd. 		025-83697070 product@chemlin.com.cn CHINA 3012 60
Zjartschem 		+86-571-8723 8903 jocelynpan@zjarts.com jocelynpan@zjarts.com CHINA 993 58
Supplier Advantage
Shanghai Hengmao New Materials Technology CO., LIMITED
58
ZHEJIANG JIUZHOU CHEM CO., LTD
58
Dorne Chemical Technology co. LTD 		58
Shandong Hanjiang Chemical Co., Ltd 		58
Wuhan Xinhao Biotechnology Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Nanjing ChemLin Chemical Industry Co., Ltd. 		60
Zjartschem 		58

View Lastest Price from 4-Chloro-4'-fluorobutyrophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Chloro-4'-fluorobutyrophenone pictures 2024-04-16 4-Chloro-4'-fluorobutyrophenone
3874-54-2
 US $10.00 / ASSAYS 1ASSAYS 99% 10 ton Dorne Chemical Technology co. LTD
4-Chloro-4'-fluorobutyrophenone pictures 2024-04-12 4-Chloro-4'-fluorobutyrophenone
3874-54-2
 US $0.00 / kg 1kg 0.99 10T Shandong Hanjiang Chemical Co., Ltd
4-Chloro-4'-fluorobutyrophenone pictures 2024-04-02 4-Chloro-4'-fluorobutyrophenone
3874-54-2
 US $10.00-100.00 / kg 1kg 99% 5000 Metric Ton/Month Wuhan Xinhao Biotechnology Co., Ltd

4-Chloro-4'-fluorobutyrophenone Spectrum

4-Chloro-4'-fluorobutyrophenone(3874-54-2)MS4-Chloro-4'-fluorobutyrophenone(3874-54-2)1HNMR4-Chloro-4'-fluorobutyrophenone(3874-54-2)13CNMR4-Chloro-4'-fluorobutyrophenone(3874-54-2)IR14-Chloro-4'-fluorobutyrophenone(3874-54-2)Raman

3874-54-2(4-Chloro-4'-fluorobutyrophenone)Related Search:

4-Fluorobenzaldehyde 2-Butanone oxime Epichlorohydrin 4-Methyl-2-pentanone Transfluthrin
Florfenicol N-(4'-fluorobutyrophenone)-4-(4-chlorophenyl)pyridinium HALOPERIDOL RELATED COMPOUND A (15 MG) (4,4'-BIS[(4-P-CHLOROPHENYL)-4-HYDROXY-PIPERIDINO]-BU-TYROPHENONE) 3-CHLORO-4'-FLUOROPROPIOPHENONE 4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(3-ethyl-4-fluorophenyl)-1-butanone
Haloperidol EP Impurity E GUTXTARXLVFHDK-GIVHGBEGSA-N 4-[4-(4-chloro-2,3,5,6-tetradeuteriophenyl)-4-hydroxy-1-oxidopiperidin-1-ium-1-yl]-1-(4-fluorophenyl)butan-1-one Dechloro Haloperidol (Haloperidol Impurity B) Cyclopropyl 4-fluorophenyl ketone
Haloperidol EP Impurity F 4-CHLORO-1-(2-FLUOROPHENYL)-1-OXOBUTANE 1-(4-FLUOROPHENYL)-4-HYDROXYBUTAN-1-ONE

1of4

3-CHLOROPROPYL4-FLUOROPHENYLKETONE/4-CHLORO-4''-FLUOROBUTYROPHENONE 1-Butanone, 4-chloro-1-(4-fluorophenyl)- 1-(4-Fluorophenyl)-4-chloro-1-butanone γ-Chloro-4'-fluorobutyrophenone ω-Chloro-4'-fluorobutyrophenone Chloro-4'-fluorobutyrophe 4-Chloro-4'-fluorobu 4-chloro-4-fluorophenyl ketone 1-Chloro-4-(4-fluorophenyl)-4-oxobutane 3-(4-Fluorophenylcarbonyl)-1-chloropropane NSC 87082 4-Chloro-4'-fluoro-butyrophenone (OR) 3-(4-Fluorobenzoyl)propyl chloride 3-(p-Fluorobenzoyl)propyl chloride GAMMA-CHLORO-4-FLUOROBUTYROPHENONE GAMMA-CHLORO-P-FLUOROBUTYROPHENONE G-CHLORO-P-FLUOROBUTYROPHENONE AKOS BBS-00006481 4-CHLORO-1-(4-FLUOROPHENYL)-1-BUTANONE 4-CHLORO-1-(4-FLUOROPHENYL)-1-OXOBUTANE 4-CHLORO-4'-FLUOROBUTYROPHENONE 3-CHLOROPROPYL 4-FLUOROPHENYL KETONE TIMTEC-BB SBB003536 3-Chloro-4'-fluorobutyrophenone 4-(4-Fluorophenyl)-4-oxobutyl chloride 4-(p-Fluorophenyl)-4-oxobutyl chloride 4-chloro-1-(4-fluorophenyl)-1-butanon 4-Chloro-p-fluorobutyrophenone 4-Fluorobenzoylpropyl chloride Butyrophenone, 4-chloro-4'-fluoro- omega-Chloro-4-fluorobutyrophenone omega-Chloro-p-fluorobutyrophenone p-Fluoro-4-chlorobutyrophenone p-Fluorobenzoylpropyl chloride p-Fluoro-gamma-chlorobutyrophenone p-Fluoro-omega-chlorobutyrophenone Chloropfluorobutyrophenone OMEGA-CHLORO-4-FLUOROBUTYROPHENONE 97& 4-Chloro-4'-fluorobutyrophenone 97% 4-Chloro-4'-fluorobutyrophenone97% 4-CHLORO-4"-FLUOROBURYROPHENONE LUMAT-009 4-Cloro-4'-fluorobutirrofenone 4-CHLORO-4'-FLUOROBUTYROPHENONE BATCH NO: CFKT-10923/0319/FP/001 4-Chloro-4’-fluoro-butyrophenone (OR) 3-Chloropropyl-4-fluorophenyl ketone JACS-3874-54-2 4-Chloro-4'-fluorobutyrophenone > uorobutyrophenone Haloperidol Impurity 1 Haloperidol Decanoate Impurity 17 99% Purity 4-Chloro-4'-fluorobutyrophenone High Quality 4-Chloro-4'-fluorobutyrophenone 4-chloro-4 '-flubutanone 4-Chloro-4'Fluorobutyrophenone (FBP) 4-Chloro-4'-fluoroacetophenone 4-CHLORO-4-FLUOROBUTYROPHENONE Haloperidol Impurity 8 Chloro-fluoro-butyrophenone Azaperone,Droperidol, Haloperidole,Timiperone