ChemicalBook >> CAS DataBase List >>1,2-O-Isopropylidene-a-L-xylofuranose

1,2-O-Isopropylidene-a-L-xylofuranose

CAS No.
114861-22-2
Chemical Name:
1,2-O-Isopropylidene-a-L-xylofuranose
Synonyms
SOTA-002;1,2-O-Isopropylidene-α-L-xylofuranose;1,2-O-isopropylidene-α-L-xylofuranose;1,2-O-Isopropylidene-a-L-xylofuranose;1,2-O-Isopropylidene-alpha-L-xylofuranose;a-L-Xylofuranose,1,2-O-(1-methylethylidene)-;α-L-Xylofuranose, 1,2-O-(1-Methylethylidene)-;2,3,5-Tri-O-benzoyl-α-D-arabinofuranosyl Bromide;(3AS,5S,6R,6AS)-5-(HYDROXYMETHYL)-2,2-DIMETHYL-3A,5,6,6A-TETRAHYDROFURO[2,3-D][1,3]DIOXOL-6-OL
CBNumber:
CB31231282
Molecular Formula:
C8H14O5
Molecular Weight:
190.19
MDL Number:
MFCD00010529
MOL File:
114861-22-2.mol
MSDS File:
SDS
Last updated:2023-02-21 10:37:17

1,2-O-Isopropylidene-a-L-xylofuranose Properties

Boiling point 333.0±37.0 °C(Predicted)
Density 1.267±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 13.23±0.60(Predicted)

1,2-O-Isopropylidene-a-L-xylofuranose price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 293718 1,2-O-Isopropylidene-a-L-xylofuranose 114861-22-2 1g $375 2021-12-16 Buy
Medical Isotopes, Inc. O106876 1-2-O-Isopropylidene-α-L-xylofuranose 114861-22-2 1g $390 2021-12-16 Buy
Biosynth Carbosynth MI01012 1,2-O-Isopropylidene-a-L-xylofuranose 114861-22-2 10g $472.5 2021-12-16 Buy
Medical Isotopes, Inc. O106876 1-2-O-Isopropylidene-α-L-xylofuranose 114861-22-2 5G $663 2021-12-16 Buy
AK Scientific 5596CR (3As,5S,6R,6aS)-5-(Hydroxymethyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol 114861-22-2 10g $687 2021-12-16 Buy
Product number Packaging Price Buy
293718 1g $375 Buy
O106876 1g $390 Buy
MI01012 10g $472.5 Buy
O106876 5G $663 Buy
5596CR 10g $687 Buy

1,2-O-Isopropylidene-a-L-xylofuranose Chemical Properties,Uses,Production

Uses

1,2-O-Isopropylidene-a-L-xylofuranose can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly in laboratory research and development processes and chemical production processes.

Synthesis

1.jpg
((3aS,5R,6S,6aS)-6-Hydroxy-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-5-yl)(morpholino)methanone (134). Step 1) (3aS,5S,6R,6aS)-5-(Hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-6-ol. To a suspension of L-(-)-xylose (133, 19.15 g, 127.5 mmol) and MgSO4 (30.72 g, 255.0 mmol) in acetone (190 mL) was added conc. H2SO4 (1.9 mL) at room temperature. After 12 h, the reaction mixture (all L-(-)-xylose had been consumed) was filtered and the collected solids were washed with acetone (twice, 20 mL per wash). The stirring yellow filtrate was neutralized with NH4OH solution to pH ~ 9. The suspended solids were removed by filtration. The filtrate was concentrated to afford crude bis-acetonide intermediate as yellow oil. The yellow oil was suspended in water (5 mL), and then the pH was adjusted from 9 to 2 with 1 N HCl in water solution. The reaction mixture was stirred for 12 h at room temperature. The resulting mixture was neutralized by the addition of 25% (w/w) K3PO4 in water until pH ~ 7. The mixture was extracted with EtOAc. The organic layer was dried over MgSO4 filtered, and concentrated in vacuo. The crude product was purified by silica gel column chromatography. Yield: (12.63 g, 52%) as yellow oil. 1H NMR (400 MHz, CD3OD) δ 5.88 (d, J = 4.0 Hz, 1H), 4.47 (d, J 4.0 Hz, 1H), 4.18-4.14 (m, 1H), 4.1 1 (d, J = 2.8 Hz, 1H), 3.83-3.71 (m, 2H), 1.45 (s, 3H), 1.29 (s, 3H).

131156-47-3
114861-22-2
Synthesis of 1,2-O-Isopropylidene-a-L-xylofuranose from α-L-Xylofuranose,1,2:3,5-bis-O-(1-Methylethylidene)-
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View Lastest Price from 1,2-O-Isopropylidene-a-L-xylofuranose manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,2-O-Isopropylidene-α-L-xylofuranose pictures 2023-02-22 1,2-O-Isopropylidene-α-L-xylofuranose
114861-22-2
US $0.00 / G 1G 98%min 30kg/month WUHAN FORTUNA CHEMICAL CO., LTD
1,2-O-Isopropylidene-a-L-xylofuranose pictures 2019-09-05 1,2-O-Isopropylidene-a-L-xylofuranose
114861-22-2
US $6.00 / KG 1KG 95%-98% 100 Career Henan Chemical Co
1,2-O-Isopropylidene-a-L-xylofuranose 1,2-O-Isopropylidene-alpha-L-xylofuranose α-L-Xylofuranose, 1,2-O-(1-Methylethylidene)- (3AS,5S,6R,6AS)-5-(HYDROXYMETHYL)-2,2-DIMETHYL-3A,5,6,6A-TETRAHYDROFURO[2,3-D][1,3]DIOXOL-6-OL 1,2-O-isopropylidene-α-L-xylofuranose SOTA-002 a-L-Xylofuranose,1,2-O-(1-methylethylidene)- 1,2-O-Isopropylidene-α-L-xylofuranose 2,3,5-Tri-O-benzoyl-α-D-arabinofuranosyl Bromide 114861-22-2