ChemicalBook >> CAS DataBase List >>7H-Pyrrolo[2,3-d]pyrimidine-5-carboxamidoxime, 4-amino-7-.beta.-D-ribo furanosyl-
7H-Pyrrolo[2,3-d]pyrimidine-5-carboxamidoxime, 4-amino-7-.beta.-D-ribo furanosyl-
![7H-Pyrrolo[2,3-d]pyrimidine-5-carboxamidoxime, 4-amino-7-.beta.-D-ribo furanosyl- Structure](CAS/GIF/22242-89-3.gif)
- CAS No.
- 22242-89-3
- Chemical Name:
- 7H-Pyrrolo[2,3-d]pyrimidine-5-carboxamidoxime, 4-amino-7-.beta.-D-ribo furanosyl-
- Synonyms
- NSC 107512;7H-Pyrrolo[2,3-d]pyrimidine-5-carboxamidoxime, 4-amino-7-.beta.-D-ribo furanosyl-;4-Amino-Nhydroxy-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboximidamide;7H-Pyrrolo[2,3-d]pyrimidine-5-carboximidamide, 4-amino-N-hydroxy-7-β-D-ribofuranosyl-
- CBNumber:
- CB31244110
- Molecular Formula:
- C12H16N6O5
- Molecular Weight:
- 324.29
- MDL Number:
- MOL File:
- 22242-89-3.mol
Last updated:2023-05-21 10:59:17
| Boiling point | 746.5±70.0 °C(Predicted) |
|---|---|
| Density | 2.10±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C, protect from light, stored under nitrogen |
| solubility | DMSO : 170 mg/mL (524.22 mM; Need ultrasonic) |
| pka | 6.16±0.69(Predicted) |
7H-Pyrrolo[2,3-d]pyrimidine-5-carboxamidoxime, 4-amino-7-.beta.-D-ribo furanosyl- Chemical Properties,Uses,Production
Biological Activity
NSC 107512 is a potent inhibitor of cyclin-dependent kinase 9 (CDK9). NSC 107512 is a class of sangivamycin-like molecules (SLM). NSC 107512 inhibits growth and induces apoptosis of multiple myeloma tumors[1].
References
[1]. Dolloff NG, et al. Sangivamycin-like molecule 6 exhibits potent anti-multiple myeloma activity through inhibition of cyclin-dependent kinase-9. Mol Cancer Ther. 2012;11(11):2321-2330.
7H-Pyrrolo[2,3-d]pyrimidine-5-carboxamidoxime, 4-amino-7-.beta.-D-ribo furanosyl- Preparation Products And Raw materials
Raw materials
Preparation Products
7H-Pyrrolo[2,3-d]pyrimidine-5-carboxamidoxime, 4-amino-7-.beta.-D-ribo furanosyl- Suppliers
Global( 5)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| NewCan Biotech Limited | +86-0571-86912261 +8613735419629 | sales@newcanbio.com | China | 9976 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24018 | 58 |
| Shanghai?Medlife?Pharm-Tech?Co.,?Ltd | 021-59167510 18117107507 | vip@med-life.cn | China | 5019 | 58 |
| Supplier | Advantage |
|---|---|
| NewCan Biotech Limited | 58 |
| Aladdin Scientific | 58 |
| TargetMol Chemicals Inc. | 58 |
| Shanghai?Medlife?Pharm-Tech?Co.,?Ltd | 58 |
7H-Pyrrolo[2,3-d]pyrimidine-5-carboxamidoxime, 4-amino-7-.beta.-D-ribo furanosyl-
7H-Pyrrolo[2,3-d]pyrimidine-5-carboximidamide, 4-amino-N-hydroxy-7-β-D-ribofuranosyl-
NSC 107512
4-Amino-Nhydroxy-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboximidamide
22242-89-3