ChemicalBook >> CAS DataBase List >>AC-5216
AC-5216
- CAS No.
- 226954-04-7
- Chemical Name:
- AC-5216
- Synonyms
- CS-2606;AC-5216;XBD-173;Mapunil;EMapunil;AC-5216,XBD-173;Emapunil(AC-5216);AC 5216 (Emapunil);XBD173 >=98% (HPLC);AC-5216;XBD-173;EMAPUNIL;AC5216;AC 5216
- CBNumber:
- CB32448636
- Molecular Formula:
- C23H23N5O2
- Molecular Weight:
- 401.46
- MDL Number:
- MFCD07772312
- MOL File:
- 226954-04-7.mol
Last updated:2023-06-30 15:45:59
| storage temp. | 2-8°C |
|---|---|
| solubility | DMF: 30 mg/mL; DMF:PBS (pH 7.2) (1:20): 0.05 mg/mL; DMSO: 5 mg/mL |
| form | powder |
| color | white to beige |
| FDA UNII | OG837L732J |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P501 | |||||||||
| NFPA 704 |
|
AC-5216 price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1223 | XBD173 ≥98% (HPLC) | 226954-04-7 | 5MG | $118 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1223 | XBD173 ≥98% (HPLC) | 226954-04-7 | 25MG | $462 | 2024-03-01 | Buy |
| Cayman Chemical | 18522 | AC-5216 ≥98% | 226954-04-7 | 1mg | $34 | 2024-03-01 | Buy |
| Cayman Chemical | 18522 | AC-5216 ≥98% | 226954-04-7 | 5mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 18522 | AC-5216 ≥98% | 226954-04-7 | 10mg | $183 | 2024-03-01 | Buy |
AC-5216 Chemical Properties,Uses,Production
Uses
Emapunil possesses anxiolytic and antidepressant-like effects and a ligand for translocator protein (TSPO), which plays an important role in the depression treatment.
Biochem/physiol Actions
XBD173 (emapunil, AC-5216) is a potent and selective translocator protein 18 kDa (TSPO) ligand with a Ki value of 0.297 nM. XBD173 acts at the TSPO translocator protein, formerly called the peripheral benzodiazepine receptor, which is involved in production of neuroactive steroids such as allopregnanolone in the brain. TSPO carries cholesterol from the outer to the inner mitochondrial membrane, which is the rate-limiting step of steroidogenesis. XBD173 enhances GABA-mediated neurotransmission via induction of neurosteroidogenesis and exhibits anti-anxiety and antidepressant-like effects.
storage
Store at +4°C
AC-5216 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 90)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Chemia Biotechnology（Shanghai） Co., Ltd | +8613816753574 | info@chemia-pharm.com | CHINA | 311 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9991 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
226954-04-7(AC-5216)Related Search:
EMapunil
XBD-173
N-Benzyl-N-ethyl-2-(7-Methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetaMide
9H-Purine-9-acetaMide,N-ethyl-7,8-dihydro-7-Methyl-8-oxo-2-phenyl-N-(phenylMethyl)-
AC 5216 (Emapunil)
N-Ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-N-(phenylmethyl)-9H-purine-9-acetamide
Emapunil(AC-5216)
AC-5216
CS-2606
AC-5216;XBD-173;EMAPUNIL;AC5216;AC 5216
XBD173 >=98% (HPLC)
9H-Purine-9-acetaMide,N-ethyl-7,8-dihydro-7-Methyl-8-oxoChemicalbook-2-phenyl-N-(phenylMethyl)-
Mapunil
N-benzyl-N-ethyl-2-(7-methyl-8-oxo-2-phenyl-7H-purin-9(8H)-yl)acetamide
PTSD,depression,T2DM,AC 5216,antianxiety,Emapunil,XBD 173,disorder,traumatic,MBR,neuroprotective,inhibit,post,XBD173,Antidepressant,AC5216,Inhibitor,stress,anti-inflammatory
AC-5216,XBD-173
226954-04-7
Inhibitors