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Deoxyarbutin

Deoxyarbutin structure

CAS No.: 53936-56-4

Chemical Name:: Deoxyarbutin

Synonyms: Tetrahydropyranyloxyphenol;Dexyarbutin;Deoxyarbutin;LGB-D ARBUTIN;Deoxyarbutin, 98%+;Deoxyarbutin 53936-56-4;Tranexamic acid 701-54-2;Pure Deoxyarbutin Powder;4-[(2-Tetrahydropyranyl)oxy]phenol;4-(TETRAHYDRO-2H-2-PYRANYLOXY)PHENOL

CBNumber:: CB32473685

Molecular Formula:: C11H14O3

Molecular Weight:: 194.23

MDL Number:: MFCD09970981

MOL File:: 53936-56-4.mol

MSDS File:: SDS

Last updated:2024-04-23 17:50:46

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Deoxyarbutin Properties

Melting point	88-89 °C(Solv: ligroine (8032-32-4))
Boiling point	349.8±32.0 °C(Predicted)
Density	1.174
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Sonicated)
pka	10.10±0.15(Predicted)
form	Solid
color	White to Off-White
Stability	Hygroscopic
FDA UNII	RG969BY5EN

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P305+P351+P338

HS Code

2932990090

NFPA 704

	0
2		0

Deoxyarbutin price More Price(37)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	21077	Deoxyarbutin	53936-56-4	10g	$49	2024-03-01	Buy
Cayman Chemical	21077	Deoxyarbutin	53936-56-4	250g	$593	2024-03-01	Buy
Cayman Chemical	21077	Deoxyarbutin	53936-56-4	50g	$216	2024-03-01	Buy
Cayman Chemical	21077	Deoxyarbutin	53936-56-4	100g	$263	2024-03-01	Buy
TRC	D232105	Deoxyarbutin	53936-56-4	50mg	$105	2021-12-16	Buy

Product number	Packaging	Price	Buy
21077	10g	$49	Buy
21077	250g	$593	Buy
21077	50g	$216	Buy
21077	100g	$263	Buy
D232105	50mg	$105	Buy

Deoxyarbutin Chemical Properties,Uses,Production

Description

Deoxyarbutin is a tyrosinase inhibitor (IC₅₀ = 17.5 μM for mushroom tyrosinase). It reduces melanin content in isolated dark human melanocytes when used at a concentration of 1.56 μM. Topical administration of deoxyarbutin (5%) induces skin lightening in human skin mouse xenograft models. Deoxyarbutin also inhibits proliferation of B16/F10 murine melanoma cells (EC₅₀ = 39.56 μM). It induces apoptosis and halts the cell cycle at the S phase in B16/F10 cells when used at a concentration of 50 μM. Deoxyarbutin (50 mg/kg) reduces tumor growth in a B16/F10 murine melanoma model.

Uses

Deoxyarbutin acts as a skin whitening agent through the inhibition of tyrosinase. A safer alternative to the use of hydroquinone and arbutin.

Preparation

Deoxyarbutin is a derivative of ?-arbutin, obtained by removal of hydroxyl groups from the glucose side-chain of ?-arbutin.

Deoxyarbutin synthesis

Synthesis of Deoxyarbutin from 2H-Pyran, tetrahydro-2-[4-(phenylmethoxy)phenoxy]-

Deoxyarbutin Preparation Products And Raw materials

Raw materials

Preparation Products

Deoxyarbutin Suppliers

Global( 344)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Changzhou Ditong Chemical Co.,Ltd	+86-0519-88299272	info@edengenechem.com	China	2169	58
Shaanxi Haibo Biotechnology Co., Ltd	+undefined18602966907	qinhe02@xaltbio.com	China	1000	58
Chongqing Zhihe Biopharmaceutical Co., Ltd.	+86-18580541567 +86-17782035140	sales@zhswyy.com	China	338	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	+8613343047651	admin@zlchemi.com	China	290	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418679 +86-18949832763	info@tnjchem.com	China	2989	55
Shanxi Naipu Import and Export Co.,Ltd	+86-13734021967 +8613734021967	kaia@neputrading.com	China	1011	58
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58

Supplier	Advantage
Changzhou Ditong Chemical Co.,Ltd	58
Shaanxi Haibo Biotechnology Co., Ltd	58
Chongqing Zhihe Biopharmaceutical Co., Ltd.	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
Hefei TNJ Chemical Industry Co.,Ltd.	55
Shanxi Naipu Import and Export Co.,Ltd	58
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58

View Lastest Price from Deoxyarbutin manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-23	Deoxyarbutin 53936-56-4	US $10.00 / kg	1kg	99%	5000kg/Week	Hebei Zhuanglai Chemical Trading Co.,Ltd
2024-04-23	Deoxyarbutin 53936-56-4	US $0.00-0.00 / kg	0.10000000149011612kg	98%	20tons	Chongqing Zhihe Biopharmaceutical Co., Ltd.
2024-04-23	Deoxyarbutin 53936-56-4	US $0.00-0.00 / kg	0.10000000149011612kg	99%	20tons	Chongqing Zhihe Biopharmaceutical Co., Ltd.

Deoxyarbutin
53936-56-4
US $10.00 / kg
99%
Hebei Zhuanglai Chemical Trading Co.,Ltd

Deoxyarbutin
53936-56-4
US $0.00-0.00 / kg
98%
Chongqing Zhihe Biopharmaceutical Co., Ltd.

Deoxyarbutin
53936-56-4
US $0.00-0.00 / kg
99%
Chongqing Zhihe Biopharmaceutical Co., Ltd.

Deoxyarbutin Spectrum

Deoxyarbutin(53936-56-4)¹HNMR

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1of4

Deoxyarbutin 4-(TETRAHYDRO-2H-2-PYRANYLOXY)PHENOL 4-[(Tetrahydro-2H-pyran-2-yl)oxy]phenol Phenol,4-[(tetrahydro-2H-pyran-2-yl)oxy]- Deoxyarbutin 4-[(Tetrahydro-2H-pyran-2-yl)oxy]phenol TIANFUCHEM--53936-56-4--Deoxyarbutin factory price Deoxyarbutin, 98%+ Dexyarbutin (S)-4-(Tetrahydro-2H-pyran-2-yloxy)phenol Deoxyarbutin 53936-56-4 LGB-D ARBUTIN 4-[(2-Tetrahydropyranyl)oxy]phenol Tetrahydropyranyloxyphenol Tranexamic acid 701-54-2 Pure Deoxyarbutin Powder 53936-56-4 3936-56-4 Inhibitors Cosmetics 53936-56-4