ChemicalBook >> CAS DataBase List >>Isosorbide 5-mononitrate
Isosorbide 5-mononitrate
- CAS No.
- 16051-77-7
- Chemical Name:
- Isosorbide 5-mononitrate
- Synonyms
- ISOSORBIDE MONONITRATE;ISMN;Ismo;IMDUR;5-ismn;Vasotrate;5-ISOSORBIDE MONONITRATE;ELAN;Momt;Coronu
- CBNumber:
- CB3256697
- Molecular Formula:
- C6H9NO6
- Molecular Weight:
- 191.14
- MDL Number:
- MFCD00143462
- MOL File:
- 16051-77-7.mol
- MSDS File:
- SDS
Last updated:2023-10-27 17:04:05
| Melting point | 88-93 °C |
|---|---|
| alpha | 170 º (c=1, EtOH) |
| Boiling point | 326.86°C (rough estimate) |
| Density | 1.5784 (rough estimate) |
| refractive index | 145 ° (C=5, H2O) |
| storage temp. | -20°C Freezer |
| solubility | Undiluted isosorbide mononitrate is freely soluble in water, in acetone, in ethanol (96 per cent) and in methylene chloride. The solubility of the diluted product depends on the diluent and its concentration. |
| form | Solid |
| pka | 13.09±0.40(Predicted) |
| color | White to Off-White |
| Water Solubility | soluble |
| Merck | 5225 |
| InChIKey | YWXYYJSYQOXTPL-SLPGGIOYSA-N |
| CAS DataBase Reference | 16051-77-7(CAS DataBase Reference) |
| FDA UNII | LX1OH63030 |
| ATC code | C01DA14 |
| EPA Substance Registry System | D-Glucitol, 1,4:3,6-dianhydro-, 5-nitrate (16051-77-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS02 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H228 | |||||||||
| Precautionary statements | P210-P240-P241-P280-P370+P378 | |||||||||
| Hazard Codes | Xi-F,Xi,F | |||||||||
| Risk Statements | 36/37/38-11 | |||||||||
| Safety Statements | 37/39-16-15 | |||||||||
| RIDADR | 3251 | |||||||||
| RTECS | LZ4386500 | |||||||||
| HazardClass | 4.1 | |||||||||
| HS Code | 2932999000 | |||||||||
| Toxicity | LD50 oral in rat: 2010mg/kg | |||||||||
| NFPA 704 |
|
Isosorbide 5-mononitrate price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Alfa Aesar | J63674 | Isosorbide mononitrate, 98+% | 16051-77-7 | 5g | $193.65 | 2024-03-01 | Buy |
| Alfa Aesar | J63674 | Isosorbide mononitrate, 98+% | 16051-77-7 | 10g | $307.65 | 2024-03-01 | Buy |
| Alfa Aesar | J63674 | Isosorbide mononitrate, 98+% | 16051-77-7 | 25g | $704.65 | 2024-03-01 | Buy |
| TRC | KIT8290 | Isosorbide5-Mononitrate(1.0mg/mLinDimethylSulfoxide) | 16051-77-7 | 10x1mL | $180 | 2021-12-16 | Buy |
| Biosynth Carbosynth | MD09906 | 1,4:3,6-Dianhydro-5-nitro-D-glucitol | 16051-77-7 | 10g | $300 | 2021-12-16 | Buy |
Isosorbide 5-mononitrate Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powde
Uses
Isosorbide 5-Mononitrate is a metabolite of Isosorbide Dinitrate; used as an antianginal.
Uses
antidepressant, 5HT reuptake inhibitor
Uses
A metabolite of Isosorbide Dinitrate. Used as an antianginal
Definition
ChEBI: Isosorbide mononitrate is a nitrate ester and a glucitol derivative. It has a role as a nitric oxide donor and a vasodilator agent.
brand name
Imdur (Schering-Plough); Ismo (Dr. Reddy’s); Monoket (Schwarz Pharma) .
General Description
Isosorbide 5-mononitrate is a crystalline solid. Isosorbide 5-mononitrate is very flammable and may be toxic by ingestion.
Air & Water Reactions
Highly flammable.
Reactivity Profile
The dinitrate, a heart drug, can detonate when dry, but is non explosive with 30% of water [J. Haz.. Mater., 1992, 32(1), 87]. The mononitrate would be expected to be less reactive.
Health Hazard
Fire may produce irritating and/or toxic gases. Contact may cause burns to skin and eyes. Contact with molten substance may cause severe burns to skin and eyes. Runoff from fire control may cause pollution.
Fire Hazard
Flammable/combustible material. May be ignited by friction, heat, sparks or flames. Some may burn rapidly with flare burning effect. Powders, dusts, shavings, borings, turnings or cuttings may explode or burn with explosive violence. Substance may be transported in a molten form at a temperature that may be above its flash point. May re-ignite after fire is extinguished.
Clinical Use
Vasodilator:
Treatment and prophylaxis of angina
Adjunct in congestive heart failure
Isosorbide 5-mononitrate Preparation Products And Raw materials
Global( 403)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei baicao biology science and technology co., ltd | +86-19131911055 +8617824879454 | zhang@hbbocao.com | China | 1035 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5993 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| Jinan Shengqi pharmaceutical Co,Ltd | 86+18663751872 | christine@shengqipharm.com | CHINA | 491 | 58 |
| Casorganics US Corp | +17326109938 | sales@casorganics.com | CHINA | 174 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8823 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
View Lastest Price from Isosorbide 5-mononitrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-01-02 | Isosorbide 5-mononitrate
16051-77-7
|
US $65.00 / kg | 10kg | 0.99 | 20tons | Zibo Hangyu Biotechnology Development Co., Ltd | |
 |
2023-09-07 | Isosorbide 5-Mononitrate
16051-77-7
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-09-06 | isosorbide mononitrate
16051-77-7
|
US $50.00 / kg | 1kg | 0.99 | 20 tons | Hebei Yanxi Chemical Co., Ltd. |
-
- Isosorbide 5-mononitrate
16051-77-7
- US $65.00 / kg
- 0.99
- Zibo Hangyu Biotechnology Development Co., Ltd
-
- Isosorbide 5-Mononitrate
16051-77-7
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- isosorbide mononitrate
16051-77-7
- US $50.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
16051-77-7(Isosorbide 5-mononitrate)Related Search:
IS-5-MN
ISOSORBIDE 5-MONONITRATE
ISOSORBIDE 5-NITRATE
ELANTAN
ELAN
CORANGIN
MONOSORB
MONOCEDOCARD
MONOCLAIR
1,4:3,6-dianhydro-,5-nitrate,d-glucito
1,4:3,6-dianhydro-d-glucito5-nitrate
1,4:3,6-dianhydro-d-glucitol5-nitrate
1,4:3,6-DIANHYDRO-D-GLUCITOL 5-MONONITRATE
6-Nitrooxy-hexahydro-furo[3,2-β]furan-3-ol
6-Nitrooxy-hexahydro-furo[3,2-b]furan-3-ol
D-Glucitol, 1,4:3,6-dianhydro-, 5-nitrate
[(1R,2R,5R,6S)-6-hydroxy-4,8-dioxabicyclo[3.3.0]oct-2-yl] nitrate
ISOSORBIDE MONO ACETATE
ahr4698
bm22-145
Ososoribide-5-mononitrate
ISOSORBIDE 5-MONONITRATE, 98.5%
Corangin,Elan,Elantan,Imdur,Monocedocard,Monoclair,Monosorb
1,4:3,6-Dianhydro-D-glucitol mononitrate
1,4:3,6-Dianhydro-D-glucitd 5-mononitrate
1,4:3,6-Dianhydro-5-O-nitro-D-erythro-hexitol
IS-5-MN (ISOSORBIDE-5-MONONITRATE
(3S,3aS,6R,6aR)-6-hydroxyhexahydrofuro[3,2-b]furan-3-yl nitrate
Isosorbide-5-mononitrate min. 99%
Isosorbide Mononitrate EP
Coronu
Isomonat
Momt
Monicor
Olicard
[(3R,3aS,6S,6aR)-6-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[2,3-d]furan-3-yl nitrate
5-Nitro-1,4,3,6-dianhydro-D-glucitol
6-Nitroxoyhexahydrofuro[3,2-b]furan-3-ol
8-Nitrooxy-2,6-dioxabicyclo[3.3.0]octan-4-ol
TY-10368
Isosorbide mononitrate,contains ~30%(w/w) lactose
(3R,3aS,6S,6aR)-6-hydroxyhexahydrofuro[3,2-b]furan-3-yl nitrate
Diluted Isosorbide Mononitrate (750 mg)
ISOSORBIDE MONONITRATE(ISOSORBIDE-5-MONONITRATE)
isosorbide 5-mononitrite
Erlotinib-d17 HCl
Diluted Isosorbide Mononitrate (50%)
Isosorbide 5-Mononitrate (1.0 mg/mL in Dimethyl Sulfoxide)
Isosorbide5-Nitrate>
Isosorbide mononitrate CRS
Monoket
Mononit
Isosorbide Dinitrate EP Impurity C
Isosorbide Dinitrate Impurity 3 （Isosorbide Dinitrate EP Impurity C）
Isosorbide 5-mononitrate USP/EP/BP
DILUTED ISOSORBIDE MONONITATE 60-70%
Doravirine 13C,d3
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Isosorbide-5-mononitrate