ChemicalBook >> CAS DataBase List >>XL-388

XL-388

CAS No.
1251156-08-7
Chemical Name:
XL-388
Synonyms
XL388;CS-772;XL-388;XL 388;XL388, >=98%;XL-388;XL 388;XL-388 USP/EP/BP;Carbamazepine 298-46-4 three units, HPLC Purity : XL388;inhibit,XL388,XL 388,Mammalian target of Rapamycin,Inhibitor,mTOR,XL-388;(7-(6-Aminopyridin-3-yl)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)(3-fluoro-2-methyl-4-(methy
CBNumber:
CB32666702
Molecular Formula:
C23H22FN3O4S
Molecular Weight:
455.5
MDL Number:
MFCD24386875
MOL File:
1251156-08-7.mol
Last updated:2023-06-08 09:02:46

XL-388 Properties

Melting point >188oC (dec.)
Boiling point 738.6±60.0 °C(Predicted)
Density 1.354±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility DMSO (Slightly), Methanol (Slightly)
pka 6.22±0.13(Predicted)
form Solid
color Off-White to Pale Yellow
Stability Hygroscopic
FDA UNII B7I5G3Z7XR

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
NFPA 704
0
2 0

XL-388 price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML1239 XL388 ≥98% (HPLC) 1251156-08-7 5MG $58.4 2024-03-01 Buy
Cayman Chemical 20237 XL388 ≥98% 1251156-08-7 5mg $121 2024-03-01 Buy
Cayman Chemical 20237 XL388 ≥98% 1251156-08-7 10mg $230 2024-03-01 Buy
Cayman Chemical 20237 XL388 ≥98% 1251156-08-7 25mg $505 2024-03-01 Buy
Cayman Chemical 20237 XL388 ≥98% 1251156-08-7 50mg $903 2024-03-01 Buy
Product number Packaging Price Buy
SML1239 5MG $58.4 Buy
20237 5mg $121 Buy
20237 10mg $230 Buy
20237 25mg $505 Buy
20237 50mg $903 Buy

XL-388 Chemical Properties,Uses,Production

Uses

XL388 is a highly potent, orally bioavailable, selective, ATP-competitive mammalian target of rapamycin (mTOR) inhibitor. XL388 has shown significant and dose-dependent antitumor activity in athymic nude mice implanted with human tumor xenografts.

XL-388 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 85)Suppliers
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ATK CHEMICAL COMPANY LIMITED
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Career Henan Chemica Co
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InvivoChem
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TargetMol Chemicals Inc.
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Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8474 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Methanone, [7-(6-amino-3-pyridinyl)-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl][3-fluoro-2-methyl-4-(methylsulfonyl)phenyl]- [7-(6-Amino-3-pyridinyl)-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl][3-fluoro-2-methyl-4-(methylsulfonyl)phenyl]-methanone XL388 XL388, >=98% (7-(6-Aminopyridin-3-yl)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)(3-fluoro-2-methyl-4-(methy XL 388 XL-388 [7-(6-Amino-3-pyridinyl)-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl][3-fluoro-2-methyl-4-(methylsulfonyl)phenyl]-methanone Carbamazepine 298-46-4 three units, HPLC Purity : XL388 XL-388;XL 388 CS-772 XL-388 USP/EP/BP (7-(6-Aminopyridin-3-yl)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)(3-fluoro-2-methyl-4-(methylsulfonyl)phenyl)methanone XL388 inhibit,XL388,XL 388,Mammalian target of Rapamycin,Inhibitor,mTOR,XL-388 1251156-08-7 PI3K/Akt/mTOR Akt mTOR PI3K Inhibitors